Platelet MAO activity in alcoholic patients and their first-degree relatives. Academic Article uri icon

Overview

abstract

  • The authors studied 49 alcoholic in patients in remission, 18 first-degree relatives of 10 of these alcoholics, and 25 normal control subjects. Alcoholic patients had significantly lower platelet monoamine oxidase (MAO) activity than control subjects. There was an inverse relationship between platelet MAO levels in the alcoholic patients and prevalence of reported alcoholism in their first-degree relatives. First-degree relatives of alcoholics had lower platelet MAO activity than control subjects. The data suggest a relationship between low platelet MAO activity and predisposition to familial alcoholism.

publication date

  • November 1, 1983

Research

keywords

  • Alcoholism
  • Blood Platelets
  • Monoamine Oxidase

Identity

Scopus Document Identifier

  • 0020612409

Digital Object Identifier (DOI)

  • 10.1176/ajp.140.11.1501

PubMed ID

  • 6625002

Additional Document Info

volume

  • 140

issue

  • 11