Growth and body composition during long-term total parenteral nutrition in the rat. Academic Article uri icon

Overview

abstract

  • Detailed metabolic data indicating the adequacy of long-term total parenteral nutrition in the rat are not available. In this study an aseptic catheterization technique and a presumed adequate intravenous diet were used to support the nutrition of growing male Fischer 344 rats for a 21-day period. These animals were compared with sham-operated rats after 21 days of ad libitum access to one of two adequate oral diets. Total parenteral nutrition rats demonstrated weight gains that were similar to those in the rats consuming the oral diets. Body composition and nitrogen storage studies indicated fat and protein accumulation in total parenteral nutrition rats that were similar to those in the orally fed animals, but with a tendency toward increased fat and decreased nitrogen retention. These data indicate that apparently normal growth and development can be achieved with total parenteral nutrition in rats by meticulous attention to detail.

publication date

  • December 1, 1982

Research

keywords

  • Body Composition
  • Growth
  • Parenteral Nutrition
  • Parenteral Nutrition, Total

Identity

Scopus Document Identifier

  • 0020405085

Digital Object Identifier (DOI)

  • 10.1093/ajcn/36.6.1119

PubMed ID

  • 6816059

Additional Document Info

volume

  • 36

issue

  • 6