Rapid screening of monoclonal antibodies: new 'microstick' radioimmunoassay. Academic Article uri icon

Overview

abstract

  • A new system for assaying monoclonal antibodies consisting of an 8 x 12 array of sticks which fits into a 96-well microtiter plate is described. Tests using virus specific monoclonal antibodies and virus proteins demonstrated sensitivity equivalent to the conventional microtiter plate assay. Antibody production, antigen specific antibody, and immunoglobulin isotypes could be measured under sterile conditions directly in the original fusion mixture wells and with much greater rapidity than with the microtiter plate assay.

publication date

  • March 25, 1983

Research

keywords

  • Antibodies, Monoclonal
  • Radioimmunoassay

Identity

Scopus Document Identifier

  • 0020541417

Digital Object Identifier (DOI)

  • 10.1016/0022-1759(83)90356-3

PubMed ID

  • 6833770

Additional Document Info

volume

  • 58

issue

  • 3