Characterization of human lymphocytes which proliferate "spontaneously" in vitro. Academic Article uri icon

Overview

abstract

  • Human peripheral blood lymphocytes proliferate "spontaneously" in vitro following the reduction in the proportion of monocytes in culture. This cell proliferation, which takes place in the absence of any extrinsic antigenic stimulation, was found to reside in a small fraction of a non-T non-B cell population which was also Fc receptor-negative. Concomitant with the in vitro proliferation of the monocyte-depleted cells, an increase in the proportion of E rosette-forming cells was observed. Hence, in addition to the regulation of spontaneous proliferation of lymphocytes, it is suggested that monocytes may also be involved in the regulation of the proportion of T cells or in expression of the E-rosetting marker.

publication date

  • November 1, 1980

Research

keywords

  • Lymphocyte Activation

Identity

Scopus Document Identifier

  • 0019181227

Digital Object Identifier (DOI)

  • 10.1002/eji.1830101114

PubMed ID

  • 6970131

Additional Document Info

volume

  • 10

issue

  • 11