Hypothesis: the pathogenesis of pseudotumor cerebri. Academic Article uri icon

Overview

abstract

  • In susceptible individuals, one of a variety of known or unknown precipitants affects the arachnoid villi so as to produce a large increase in CSF outflow resistance, Ra. This increase in Ra raises CSF pressure (CSFP), which rise provokes a redistribution of arteriovenous pressures across the cerebrovascular bed. The end result is a measurable increase in cerebral blood volume, compression of the ventricular system and compromise of the convexity subarachnoid space, which further increases CSF outflow resistance. Ultimately, a new steady state CSFP is attained.

publication date

  • September 1, 1980

Research

keywords

  • Models, Biological
  • Pseudotumor Cerebri

Identity

Scopus Document Identifier

  • 0019309341

Digital Object Identifier (DOI)

  • 10.1016/0306-9877(80)90043-2

PubMed ID

  • 7001194

Additional Document Info

volume

  • 6

issue

  • 9