Metastatic retinoblastoma and L-phenylalanine mustard-dianhydrogalactitol. uri icon

Overview

abstract

  • Retinoblastomas heterotransplanted to nude mice were shown to be sensitive to a combination of phenylalanine mustard and dianhydrogalactitol. A patient with metastatic retinoblastoma was treated with this combination and had a significant response with complete clinical clearance of her bone marrow and metastatic tumors. However, the patient's response was similar to that observed in nude mice; recurrences of tumors developed after complete clinical remission.

publication date

  • January 1, 1982

Research

keywords

  • Dianhydrogalactitol
  • Eye Neoplasms
  • Melphalan
  • Retinoblastoma
  • Sugar Alcohols

Identity

Scopus Document Identifier

  • 0020463508

PubMed ID

  • 7149653

Additional Document Info

volume

  • 2

issue

  • 4