Absorption resistance of cerebrospinal fluid after subarachnoid hemorrhage in the monkey; effects of heparin. Academic Article uri icon

Overview

abstract

  • The morbidity and mortality of subarachnoid hemorrhage (SAH) is directly related to blood in the subarachnoid space. Blood was injected intracisternally in 10 monkeys, and the absorption resistance of cerebrospinal fluid (CSF) was studied. The monkeys given injections of nonheparinized blood maintained high absorptive resistances, whereas the resistances of the group that received heparinized blood returned to the original levels. If heparinization of the CSF can be achieved rapidly after SAH and the deposition of fibrin clots along the pathways of CSF drainage can be prevented, the resorption of blood through the arachnoid granulations might be facilitated.

publication date

  • December 1, 1981

Research

keywords

  • Blood
  • Cerebrospinal Fluid
  • Heparin
  • Subarachnoid Hemorrhage

Identity

Scopus Document Identifier

  • 0019853280

Digital Object Identifier (DOI)

  • 10.1227/00006123-198112000-00012

PubMed ID

  • 7322334

Additional Document Info

volume

  • 9

issue

  • 6