Chronic arterial and venous access in the unrestrained rat. Academic Article uri icon

Overview

abstract

  • A system is described for chronic cannulation of the thoracic aorta and superior vena cava in the rat. This system employs a protective stainless steel coiled spring and water tight swivel and allows chronic infusion of solutions and simultaneous intermittent blood sampling for prolonged periods of time in the undisturbed unanesthetized rat. The rats (200-250 g) lost approximately 25 g in the immediate postoperative period, but then gained weight at a relatively normal rate (cannulated rats, 2.23 g/day; control rats, 2.29 g/day).

publication date

  • April 1, 1980

Research

keywords

  • Aorta, Thoracic
  • Catheterization
  • Vena Cava, Superior

Identity

Scopus Document Identifier

  • 0019000266

Digital Object Identifier (DOI)

  • 10.1152/ajpheart.1980.238.4.H599

PubMed ID

  • 7377334

Additional Document Info

volume

  • 238

issue

  • 4