B-K mole syndrome. Cutaneous and ocular malignant melanoma. Academic Article uri icon

Overview

abstract

  • A 51-year-old white man had the B-K mole syndrome (multiple large atypical cutaneous nevi of the upper part of the trunk and extremities, inherited as an autosomal dominant trait, and thought to be more susceptible to malignant transformation), so named after two patients in whom the syndrome was first observed. Two cutaneous malignant melanomas (thigh and back) and an ocular malignant melanoma (ciliary body and iris) simultaneously developed. Patients with B-K mole syndrome have been known to have a very high risk for the development of cutaneous melanoma (including multiple primary cutaneous melanomas) and multiple primary malignancies. There may be a propensity in these patients for development of ocular melanomas.

publication date

  • August 1, 1980

Research

keywords

  • Ciliary Body
  • Eye Neoplasms
  • Iris
  • Melanoma
  • Neoplasms, Multiple Primary
  • Skin Neoplasms
  • Uveal Diseases

Identity

Scopus Document Identifier

  • 0018889533

Digital Object Identifier (DOI)

  • 10.1001/archopht.1980.01020040249006

PubMed ID

  • 7417075

Additional Document Info

volume

  • 98

issue

  • 8