Pharmacologic enhancement of gallium-67 tumor-to-blood ratios for EMT-6 sarcoma (BALB/c mice). Academic Article uri icon

Overview

abstract

  • At various intervals after intravenous injection of carrier-free 67Ga-citrate, iron dextrane or deferoxamine mesylate was injected into EMT-6 tumor-bearing BALB/c mice. After treatment, rapid clearance of 67Ga from soft tissues was observed. Tumor uptake was not greatly affected, and so increased tumor-to-blood ratios were observed. The authors conclude that these drugs can enhance target-to-nontarget uptake ratios for tumors.

publication date

  • January 1, 1979

Research

keywords

  • Deferoxamine
  • Gallium Radioisotopes
  • Iron-Dextran Complex
  • Sarcoma, Experimental

Identity

Scopus Document Identifier

  • 0018405050

Digital Object Identifier (DOI)

  • 10.1148/130.1.241

PubMed ID

  • 758657

Additional Document Info

volume

  • 130

issue

  • 1