Pelvic lymph node histiocytosis mimicking metastatic prostatic adenocarcinoma: association with hip prostheses. Academic Article uri icon

Overview

abstract

  • PURPOSE: Histological changes in lymph nodes simulating metastatic prostatic adenocarcinoma are reported. MATERIALS AND METHODS: Lymph node frozen sections from 3 patients with prostatic cancer displayed marked histiocytosis. This tissue was subjected to histochemical, immunohistochemical and electron microscopic studies. RESULTS: Only 1 erroneous diagnosis of metastasis was made. All patients had hip prostheses for at least 6 years. Tissue replacing up to 80% of lymph nodes consisted of histiocytes containing large amounts of polyethylene. CONCLUSIONS: Hip replacement predisposes the patient to have pelvic lymph node histiocytosis mimicking metastatic adenocarcinoma. This history should be communicated to the pathologist. Polyethylene is the most important factor in the cause of post-prosthesis lymph node histiocytosis.

publication date

  • August 1, 1995

Research

keywords

  • Adenocarcinoma
  • Hip Prosthesis
  • Histiocytosis
  • Lymphatic Diseases
  • Prostatic Neoplasms

Identity

Scopus Document Identifier

  • 0029046777

Digital Object Identifier (DOI)

  • 10.1097/00005392-199508000-00035

PubMed ID

  • 7609108

Additional Document Info

volume

  • 154

issue

  • 2 Pt 1