Chromosome 12 abnormalities in malignant ovarian germ cell tumors. Academic Article uri icon

Overview

abstract

  • We analyzed 3 cases of malignant ovarian germ cell tumors (MOGCTs), comprising 1 dysgerminoma and 2 immature teratomas, by banded chromosome analysis and by in situ hybridization (ISH) using a chromosome 12p painting probe. We found evidence of 12p abnormalities in two of them. A possible common genetic pathway of origin of a subset of MOGCTs with testicular germ cell tumors (TGCTs) is discussed.

publication date

  • July 1, 1995

Research

keywords

  • Chromosome Aberrations
  • Chromosomes, Human, Pair 12
  • Dysgerminoma
  • Ovarian Neoplasms
  • Teratoma

Identity

Scopus Document Identifier

  • 0029166355

Digital Object Identifier (DOI)

  • 10.1016/0165-4608(95)00067-y

PubMed ID

  • 7627937

Additional Document Info

volume

  • 82

issue

  • 1