Pfcrk-1, a developmentally regulated cdc2-related protein kinase of Plasmodium falciparum. Academic Article uri icon

Overview

abstract

  • A gene encoding a novel cdc2-related protein kinase has been identified in Plasmodium falciparum, using degenerate oligonucleotides designed to hybridise to regions that are conserved in members of the cdc2 gene family. This gene, called Pfcrk-1, is located on chromosome 4. It is most closely related to the p58GTA gene family, members of which are negative regulators of cell growth in vertebrates. Pfcrk-1 is developmentally regulated, as indicated by stage-specific accumulation of mRNA in gametocytes.

publication date

  • March 1, 1995

Research

keywords

  • CDC2 Protein Kinase
  • Plasmodium falciparum
  • Protozoan Proteins

Identity

Scopus Document Identifier

  • 0028988027

Digital Object Identifier (DOI)

  • 10.1016/0166-6851(95)00033-w

PubMed ID

  • 7637697

Additional Document Info

volume

  • 70

issue

  • 1-2