Ventroposterior medial pallidotomy in patients with advanced Parkinson's disease. Academic Article uri icon

Overview

abstract

  • In a preliminary study, the effects of ventroposterior medial pallidotomy were evaluated in five patients with advanced Parkinson's disease in whom medical therapy had failed. The mean age was 67.0 +/- 5.6 years, and the mean Hoehn and Yahr stage when "off" was 3.9 +/- 1.3. Three patients received unilateral pallidotomies; two of these received another pallidotomy after 8 weeks. Two other patients received staged bilateral pallidotomies. No significant differences in overall function could be seen before and after the first surgical procedure. All three patients with peak-dose dyskinesias or dystonia had marked contralateral reduction in these symptoms. Ventroposterior medial pallidotomy can ameliorate peak-dose dyskinesias in patients with advanced Parkinson's disease. Overall function improvement is not remarkable.

publication date

  • June 1, 1995

Research

keywords

  • Globus Pallidus
  • Parkinson Disease

Identity

Scopus Document Identifier

  • 0029013521

Digital Object Identifier (DOI)

  • 10.1227/00006123-199506000-00007

PubMed ID

  • 7643989

Additional Document Info

volume

  • 36

issue

  • 6