Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury. Academic Article uri icon

Overview

abstract

  • During blood coagulation ultrastructural lesions were produced on the platelet membrane. They were dependent on the presence of both thrombin and complement (C) and were morphologically identical to the C-dependent ultrastructural lesions (type II) seen in red cells subsequent to activation of C by the alternate mechanismmthough similar in shape they differed in size from ultrastructural lesions (type I) PRODUCED BY ACTIVATION OF C via the classic mechanismmlesions of type I were seen on the platelet surface subsequent to antibody-dependent activation of the C system.

publication date

  • June 1, 1975

Research

keywords

  • Binding Sites, Antibody
  • Blood Coagulation
  • Blood Platelets
  • Complement System Proteins

Identity

PubMed Central ID

  • PMC2189843

Scopus Document Identifier

  • 0016769985

Digital Object Identifier (DOI)

  • 10.1084/jem.141.6.1261

PubMed ID

  • 805209

Additional Document Info

volume

  • 141

issue

  • 6