Quantitative morphology of the corpus callosum in attention deficit hyperactivity disorder. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: By means of quantitative neuroanatomic imaging the authors assessed the hypothesis that there are structural brain abnormalities relevant to frontal lobe circuitry in children with attention deficit hyperactivity disorder (ADHD). METHOD: The midsagittal cross-sectional area of the corpus callosum, divided into seven sections, was measured from magnetic resonance images of 18 boys with ADHD and 18 carefully matched normal boys. RESULTS: Two anterior regions, the rostrum and the rostral body, were found to have significantly smaller areas in the ADHD group. These areas correlated in the expected direction with teacher and parent ratings of hyperactivity/impulsivity. CONCLUSIONS: This finding supports theories of abnormal frontal lobe development and function in ADHD.

publication date

  • May 1, 1994

Research

keywords

  • Attention Deficit Disorder with Hyperactivity
  • Corpus Callosum

Identity

Scopus Document Identifier

  • 0028262196

Digital Object Identifier (DOI)

  • 10.1176/ajp.151.5.665

PubMed ID

  • 8166306

Additional Document Info

volume

  • 151

issue

  • 5