Alpha-mannosidosis. Report of a case with morphologic, cytologic and immunohistochemical considerations. uri icon

Overview

abstract

  • We report the histopathologic features of the knee bone and synovium and the cytologic features of the synovial fluid from a patient with alpha-mannosidosis. The synovium showed marked papillary hyperplasia with infiltration of foamy histiocytes containing periodic acid-Schiff-positive, diastase-resistant material. Severe degenerative changes were seen in the knee bone. The synovial fluid showed increased numbers of macrophages containing periodic acid-Schiff-positive, diastase-resistant material. The differential diagnostic considerations in the synovial fluid are also discussed.

publication date

  • January 1, 1994

Research

keywords

  • Knee Joint
  • Mannosidases
  • Synovial Fluid
  • Synovial Membrane
  • alpha-Mannosidosis

Identity

PubMed ID

  • 8191839

Additional Document Info

volume

  • 38

issue

  • 3