Patch graft urethroplasty using dye enhanced laser tissue welding with a human protein solder: a preclinical canine model. Academic Article uri icon

Overview

abstract

  • We investigated the use of the KTP-532 laser to perform a patch graft urethroplasty in 24 adult male dogs using the inner preputial skin as the donor site. In group 1 (12 dogs) repairs were completed with conventional microsuturing techniques, while in group 2 (12 dogs) they were completed using the KTP-532 laser. In the laser welding group the addition of a protein solder (40% human albumin) doped with fluorescein was used. Assessment parameters included a preoperative and postoperative retrograde urethrogram, measurement of intraluminal bursting pressure in the first 6 animals in each group, operative time and histology. Operative time was 42% faster and acute intraluminal bursting pressures were significantly higher in the laser-solder group. No fistulas occurred in the laser-solder group compared to a 50% fistula rate in the suture group. Significant radiographic abnormalities were seen in the urethras of the suture repair group.

publication date

  • August 1, 1993

Research

keywords

  • Albumins
  • Laser Therapy
  • Skin Transplantation
  • Urethra

Identity

Scopus Document Identifier

  • 0027216311

Digital Object Identifier (DOI)

  • 10.1016/s0022-5347(17)35573-8

PubMed ID

  • 8326614

Additional Document Info

volume

  • 150

issue

  • 2 Pt 2