The energetics of shortening amphibian cardiac muscle. Academic Article uri icon

Overview

abstract

  • An isolated amphibian cardiac muscle preparation, toad ventricular strip, was used to examine the energetics of shortening. Simultaneous measurements of force and length changes and the associated heat production were made. Both the isometric heat/stress and the enthalpy (heat+work)/load relationships were similar to those previously reported in mammalian cardiac muscle. The activation metabolism was higher in this preparation and, like its mammalian counterpart, was length dependent. The heat production measured in an isometric contraction was approximately 50% higher than that observed at the same stress level in rodent mammalian cardiac muscle. This did not affect the maximum isotonic mechanical efficiency (work divided by enthalpy) of the preparation which, at an afterload of 20% of the maximum stress was 18.1 +/- 1.7% (n = 8). There was no evidence for a shortening heat component in this preparation during isotonic contractions. It appears therefore that the energetics of shortening amphibian cardiac muscle closely resemble the energetics of mammalian cardiac tissue.

publication date

  • June 1, 1993

Research

keywords

  • Energy Metabolism
  • Myocardial Contraction
  • Myocardium

Identity

Scopus Document Identifier

  • 0027309464

Digital Object Identifier (DOI)

  • 10.1007/BF00375105

PubMed ID

  • 8351207

Additional Document Info

volume

  • 424

issue

  • 1