Bladder calcifications after photodynamic therapy: analysis of a rare complication. uri icon

Overview

abstract

  • OBJECTIVES: We analyzed bladder calcifications occurring after photodynamic therapy administered for the treatment of superficial bladder cancer, a finding not previously reported after this treatment. METHODS: Bladder biopsies from 20 patients undergoing photodynamic therapy were evaluated. Bladder calcifications were identified in 2 patients and analyzed for composition. RESULTS: One patient had diffuse microcrystalline deposition in two biopsies composed of calcium oxalate monohydrate A. A second patient had a focal stone at a healing biopsy site composed of monoclinic calcium hydrogen phosphate dihydrate (brushite) (66%), calcium oxalate (25%), hydroxyapatite (6%), and protein (3%). CONCLUSIONS: Rare calcium oxalate and brushite calcifications were identified after photodynamic therapy and presumed to occur because of tissue injury associated with treatment.

publication date

  • June 1, 1996

Research

keywords

  • Calcinosis
  • Photochemotherapy
  • Urinary Bladder Diseases

Identity

Scopus Document Identifier

  • 0029890501

Digital Object Identifier (DOI)

  • 10.1016/S0090-4295(96)00047-7

PubMed ID

  • 8677572

Additional Document Info

volume

  • 47

issue

  • 6