Contralateral temporal hypometabolism on positron emission tomography in temporal lobe epilepsy. uri icon

Overview

abstract

  • INTRODUCTION: No detailed case studies report lateralised hypometabolism on positron emission tomography (PET) contralateral to the epileptogenic focus in temporal lobe epilepsy (TLE). MATERIAL AND METHODS: We performed 18F fluorodeoxyglucose (FDG) PET in two intractable TLE patients. RESULTS: One had right temporal interictal spikes on electroencephalography (EEG) and a right medial temporal lobe lesion on magnetic resonance imaging (MRI). FDG-PET showed decreased uptake in the left temporal lobe. Right temporal ictal onset, with bilateral interictal epileptiform activity, occurred on intracranial EEG. He is seizure free after right temporal lobectomy and ganglioglioma resection. The second had right temporal lobe interictal and ictal EEG activity. MRI demonstrated right anteriomedial temporal increased T2 signal. Neuropsychology revealed bilateral cognitive dysfunction. FDG-PET showed left anterior temporal and lateral frontal hypometabolism. He is seizure free after right temporal lobectomy. CONCLUSION: These findings suggest that regional uptake asymmetry on FDG-PET may be give misleading lateralising information in TLE.

publication date

  • January 1, 1996

Research

keywords

  • Blood Glucose
  • Dominance, Cerebral
  • Energy Metabolism
  • Epilepsy, Temporal Lobe
  • Temporal Lobe
  • Tomography, Emission-Computed

Identity

Scopus Document Identifier

  • 0029876238

Digital Object Identifier (DOI)

  • 10.1111/j.1600-0404.1996.tb00178.x

PubMed ID

  • 8741122

Additional Document Info

volume

  • 93

issue

  • 2-3