Uterine arcuate artery Doppler and decidual microvascular pathology in pregnancies complicated by type I diabetes mellitus. Academic Article uri icon

Overview

abstract

  • The objective was to correlate Doppler indices from the uterine arcuate arteries with an analysis of the decidual vascular histology in patients with type I diabetes. Pulsed wave Doppler was used to sample the uterine arcuate artery system beneath the placenta within 8 days of delivery in 47 patients with type I diabetes mellitus. A placental pathologist, without knowledge of either clinical outcome or Doppler information, classified the histological appearance of the decidual arteries as normal, type A (hyalinization, mural thickening), or type B (fibrinoid necrosis, atherosis, thrombosis). Patients were then grouped according to the histology of the decidual arteries. An analysis of variance (ANOVA) of the systolic/diastolic (S/D) ratios (log. S/D) showed significant variation (p < 0.025). A multiple range comparison test showed that patients with normal or only mildly abnormal (type A) vessels had similar values, whereas those with severe vasculopathy (type B) had significantly higher S/D ratios (p < 0.05). The study confirmed a relationship between arcuate artery Doppler indices and downstream decidual vascular pathology.

publication date

  • August 1, 1996

Research

keywords

  • Decidua
  • Diabetes Mellitus, Type 1
  • Pregnancy in Diabetics
  • Ultrasonography, Doppler, Color
  • Uterus

Identity

Scopus Document Identifier

  • 0030204017

Digital Object Identifier (DOI)

  • 10.1046/j.1469-0705.1996.08020098.x

PubMed ID

  • 8883311

Additional Document Info

volume

  • 8

issue

  • 2