Resection and immediate microvascular reconstruction in the management of osteoradionecrosis of the mandible. Academic Article uri icon

Overview

abstract

  • BACKGROUND: Management of osteoradionecrosis (ORN) remains a difficult and challenging problem. The traditional approach using debridement, antibiotics, and occasionally hyperbaric oxygen is usually successful in treating minimal ORN. However, when bone and soft-tissue necrosis is extensive, the conservative approach usually requires intensive care over a long period of time and often yields unsatisfactory functional and cosmetic results. METHODS: Within the past 5 years, we have used radical resection of the mandible with immediate microvascular reconstruction in the treatment of extensive ORN of the mandible. This aggressive surgical approach was used in six patients with advanced ORN of the mandible, all of whom had failed initial conservative treatment, including hyperbaric oxygen therapy in three. A fibular free graft with microvascular anastomosis was used in all patients. RESULTS: All the patients healed primarily with minimal postoperative morbidity and excellent cosmetic results. Two patients subsequently required removal of some of their hardware. One patient had placement of osseointegrated implants with an excellent cosmetic and functional result. CONCLUSION: Microvascular reconstruction with its own blood supply seems to expedite bone healing and limit further osteoradionecrosis of the remaining mandible. Although prevention is the primary goal in radiation injury, our experience suggests that radical resection with free microvascular reconstruction offers significant advantages to selected patients with extensive ORN of the mandible.

publication date

  • August 1, 1997

Research

keywords

  • Mandibular Diseases
  • Osteoradionecrosis

Identity

Scopus Document Identifier

  • 0030795779

Digital Object Identifier (DOI)

  • 10.1002/(sici)1097-0347(199708)19:5<406::aid-hed7>3.0.co;2-3

PubMed ID

  • 9243268

Additional Document Info

volume

  • 19

issue

  • 5