Invasive Aspergillus sinusitis during bone marrow transplantation. uri icon

Overview

abstract

  • Aspergillus sinusitis is usually a lethal condition in bone marrow transplanted patients. We report the case of a patient known to have a sinus infection with Aspergillus flavus before treatment with allogenic bone marrow transplantation for a refractory acute myelogenous leukemia. Exacerbation of the sinusitis during the neutropenic period required a multidisciplinary approach. Cure was achieved after treatment with a combination of surgery (Caldwell-Luc procedure), long term ABCD (amphotericin B colloidal dispersion) therapy (7 months) and granulocyte transfusions during the period preceding engraftment. The use of granulocyte transfusion in this salvage setting is discussed. Aggressive multimodality management of aspergillus sinusitis in immunosuppressed patients may lead to a cure and might not preclude allogenic transplantation.

publication date

  • January 1, 1997

Research

keywords

  • Aspergillosis
  • Bone Marrow Transplantation
  • Sinusitis

Identity

Scopus Document Identifier

  • 0030656421

Digital Object Identifier (DOI)

  • 10.3109/00365549709011849

PubMed ID

  • 9360268

Additional Document Info

volume

  • 29

issue

  • 4