Glomerulomegaly and proteinuria in a patient with idiopathic pulmonary hypertension. uri icon

Overview

abstract

  • Glomerulomegaly is a histologic finding present in idiopathic pulmonary hypertension, congenital cyanotic heart disease, morbid obesity associated with sleep apnea syndrome, sickle cell disease, and polycythemic states. This study examines the case of a 34-yr-old woman with idiopathic pulmonary artery hypertension who presented with nephrotic-range proteinuria. Kidney biopsy revealed enlarged glomeruli with mesangial-proliferative glomerulonephritis. A review of the pertinent literature and a discussion of the proposed pathophysiologic mechanisms leading to glomerulomegaly are presented.

publication date

  • December 1, 1997

Research

keywords

  • Glomerulonephritis, Membranoproliferative
  • Hypertension, Pulmonary
  • Kidney Glomerulus
  • Nephrotic Syndrome
  • Proteinuria

Identity

Scopus Document Identifier

  • 0031430419

Digital Object Identifier (DOI)

  • 10.1681/ASN.V8121966

PubMed ID

  • 9402101

Additional Document Info

volume

  • 8

issue

  • 12