Evaluation of early second trimester maternal serum creatine kinase isoenzyme BB as a marker of poor pregnancy outcome. Academic Article uri icon

Overview

abstract

  • We hypothesized that maternal serum levels of the isoenzyme creatine kinase (CK)-BB, which is highly expressed in the placenta, may be elevated during the early second trimester in gestations destined to deliver prematurely or of a small-for-gestational-age infant (birthweight below 10th percentile). To test this hypothesis, we compared maternal serum CK-BB levels and percentage of CK-BB over total CK, in 69 normal pregnancies (delivering at term of appropriate-for-gestational-age infants) with those of 25 cases complicated by preterm delivery at < or = 34 weeks (n = 14), of a small-for-gestational-age infant (n = 8), or both (n = 3). No differences were present in maternal serum CK BB levels between normal and complicated pregnancies. Moreover, no correlation was found between gestational age at delivery and CK BB levels (r = 0.03; p = 0.7).

publication date

  • January 1, 1997

Research

keywords

  • Creatine Kinase
  • Pregnancy Complications
  • Pregnancy Outcome

Identity

Scopus Document Identifier

  • 0031444411

Digital Object Identifier (DOI)

  • 10.1159/000264505

PubMed ID

  • 9475367

Additional Document Info

volume

  • 12

issue

  • 6