Epithelioid haemangioendothelioma of the thyroid gland: a case report and review of literature.

Overview

AIMS: This is a hitherto unreported case of an epithelioid haemangioendothelioma of the thyroid gland. METHODS AND RESULTS: The patient was a 44-year-old woman who presented with a right thyroid mass. A right subtotal thyroidectomy was performed. Histologically the lesion had characteristic epithelioid and spindle cell proliferation in a background of chondromyxoid stroma. Cytoplasmic vacuolization in the epithelioid and spindle cells was present. No atypical mitotic activity or necrosis was noted. The tumour cells were positive for factor VIII-related antigen, Ulex europeus and CD 31 and were negative for cytokeratin. CONCLUSION: The patient has been followed for 24 months and is free of recurrent and metastatic disease, which is supportive of a benign course in the thyroid gland.