Squamous cell carcinoma of the tongue in young patients: a matched-pair analysis. Academic Article uri icon

Overview

abstract

  • BACKGROUND: Tongue cancer is seen with increasing frequency in young individuals. There is controversy concerning the clinical course and outcome for oral tongue cancer in young patients. METHODS: A retrospective review of 36 patients under 40 years of age with squamous cell carcinoma of the tongue was performed. These patients were matched to an older population. The 5-year disease-free survival; rates of local, regional, and distant failure; and rate of second primary tumor were determined for both populations. RESULTS: The 5-year disease-free survival for the young patients was 62% versus 69% in the older population (p = .30). Ten of 36 (28%) of younger patients recurred locally versus five of 36 (14%) of the older patients (p = .11). Nine of 36 (25%) younger patients recurred regionally in the younger group versus six of 36 (17%) patients in the older group (p = .25). Sixteen of 36 (44%) of the younger patients had locoregional failure versus eight of 36 (22%) of the older patients (p < .05). The rates of metastatic disease and second primary lesions were similar in both populations. CONCLUSIONS: In this series, younger patients with squamous cell carcinoma of the oral tongue had a higher rate of locoregional recurrence rate than did older patients. This did not translate into a survival difference.

publication date

  • August 1, 1998

Research

keywords

  • Carcinoma, Squamous Cell
  • Neoplasm Recurrence, Local
  • Tongue Neoplasms

Identity

Scopus Document Identifier

  • 0031807026

Digital Object Identifier (DOI)

  • 10.1002/(sici)1097-0347(199808)20:5<363::aid-hed1>3.0.co;2-w

PubMed ID

  • 9663661

Additional Document Info

volume

  • 20

issue

  • 5