Case of the month: March 1998--48 year old man with back pain and weakness. uri icon

Overview

abstract

  • A 48 year old man with long history of end stage renal disease (ESRD) and secondary hyperparathyroidism presented with back pain and incontinence. MRI and CT showed T2 expansion with bony destruction and spinal cord compression. Other vertebral bodies showed destructive lesions as well. Microscopic examination showed a brown tumor composed of multinucleated giant cells and bone uninvolved by tumor showed "tunneling" resorption. Brown tumors are an exaggerated form of "local" osteitis fibrosa cystica in patients with ESRD and secondary hyperparathyroidism, but spinal cord compression is rare.

publication date

  • July 1, 1998

Research

keywords

  • Back Pain
  • Bone Neoplasms
  • Giant Cell Tumors
  • Spinal Cord Compression
  • Spine

Identity

Scopus Document Identifier

  • 0031804139

PubMed ID

  • 9669717

Additional Document Info

volume

  • 8

issue

  • 3