Bilateral optic neuropathy with IgGkappa multiple myeloma improved after myeloablative chemotherapy. uri icon

Overview

abstract

  • A 49-year-old woman with immunoglobulin GK multiple myeloma developed progressive visual loss with bilateral upper and lower central arcuate scotomas. Funduscopic and electrophysiologic studies indicated bilateral optic neuropathy. The immunoglobulin G fraction of the patient's serum reacted with retinal ganglionic cells in bovine retina. The visual abnormalities remitted after myeloablative chemotherapy and disappearance of the paraprotein.

publication date

  • January 15, 1999

Research

keywords

  • Functional Laterality
  • Immunoglobulin G
  • Immunoglobulin kappa-Chains
  • Multiple Myeloma
  • Myeloablative Agonists
  • Optic Nerve Diseases

Identity

Scopus Document Identifier

  • 0033555596

Digital Object Identifier (DOI)

  • 10.1212/wnl.52.2.414

PubMed ID

  • 9932972

Additional Document Info

volume

  • 52

issue

  • 2