Haka, Abigail Susan

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selected publications

High-density lipoprotein or cyclodextrin extraction of cholesterol from aggregated LDL reduces foam cell formation. Journal of cell science. 2019 Academic Article GET IT
Times cited: 8
TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates. Arteriosclerosis, thrombosis, and vascular biology. 2019 Academic Article GET IT
Times cited: 39
Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and Catabolism. Arteriosclerosis, thrombosis, and vascular biology. 2019 Academic Article GET IT
Times cited: 19
Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity. Cell reports. 2017 Academic Article GET IT
Times cited: 155
A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux. ACS nano. 2017 Academic Article GET IT
Times cited: 66
Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism. Journal of lipid research. 2017 Academic Article GET IT
Times cited: 11
Sphingosine kinases are not required for inflammatory responses in macrophages. The Journal of biological chemistry. 2016 Academic Article GET IT
Times cited: 3
Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation. Journal of lipid research. 2016 Academic Article GET IT
Times cited: 71
Noninvasive Detection of Inflammatory Changes in White Adipose Tissue by Label-Free Raman Spectroscopy. Analytical chemistry. 2016 Academic Article GET IT
Times cited: 14
Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse. Journal of cell science. 2016 Academic Article GET IT
Times cited: 27
Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell Formation. Arteriosclerosis, thrombosis, and vascular biology. 2015 Academic Article GET IT
Times cited: 23
Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2014 Academic Article GET IT
Times cited: 26
Identification of spermatogenesis in a rat sertoli-cell only model using Raman spectroscopy: a feasibility study. The Journal of urology. 2014 Academic Article GET IT
Times cited: 7
Sphingosine kinases are not required for inflammatory responses in macrophages. The Journal of biological chemistry. 2013 Academic Article GET IT
Times cited: 57
Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein. Arteriosclerosis, thrombosis, and vascular biology. 2013 Academic Article GET IT
Times cited: 12
Intrinsic versus laser-induced fluorescence spectroscopy for coronary atherosclerosis: a generational comparison model for testing diagnostic accuracy. Applied spectroscopy. 2012 Academic Article GET IT
Times cited: 3
Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy. PloS one. 2012 Academic Article GET IT
Times cited: 19
Mechanism of ceroid formation in atherosclerotic plaque: in situ studies using a combination of Raman and fluorescence spectroscopy. Journal of biomedical optics. 2011 Academic Article GET IT
Times cited: 28
Detection of coronary atherosclerotic plaques with superficial proteoglycans and foam cells using real-time intrinsic fluorescence spectroscopy. Atherosclerosis. 2010 Academic Article GET IT
Times cited: 13
Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins. Molecular biology of the cell. 2009 Academic Article GET IT
Times cited: 91
Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization. Arteriosclerosis, thrombosis, and vascular biology. 2009 Academic Article GET IT
Times cited: 35
Diagnosing breast cancer using Raman spectroscopy: prospective analysis. Journal of biomedical optics. 2009 Academic Article GET IT
Times cited: 165
Diagnosing breast cancer using diffuse reflectance spectroscopy and intrinsic fluorescence spectroscopy. Journal of biomedical optics. 2008 Academic Article GET IT
Times cited: 167
Determination of uncertainty in parameters extracted from single spectroscopic measurements. Journal of biomedical optics. 2007 Academic Article GET IT
Times cited: 30
Intrinsic fluorescence and diffuse reflectance spectroscopy identify superficial foam cells in coronary plaques prone to erosion. Arteriosclerosis, thrombosis, and vascular biology. 2006 Academic Article GET IT
Times cited: 30
In vivo margin assessment during partial mastectomy breast surgery using raman spectroscopy. Cancer research. 2006 Academic Article GET IT
Times cited: 378
In vivo Raman spectral pathology of human atherosclerosis and vulnerable plaque. Journal of biomedical optics. 2006 Academic Article GET IT
Times cited: 132
Diagnosing breast cancer by using Raman spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT
Times cited: 566
Real-time Raman system for in vivo disease diagnosis. Journal of biomedical optics. 2005 Academic Article GET IT
Times cited: 125
Classification of Fourier transform infrared microscopic imaging data of human breast cells by cluster analysis and artificial neural networks. Applied spectroscopy. 2003 Academic Article GET IT
Times cited: 46
Identifying microcalcifications in benign and malignant breast lesions by probing differences in their chemical composition using Raman spectroscopy. Cancer research. 2002 Academic Article GET IT
Times cited: 278
Model-based biological Raman spectral imaging. Journal of cellular biochemistry. Supplement. 2002 Academic Article GET IT
Times cited: 91

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Background

education and training

Ph.D., Massachusetts Institute of Technology 2005
A.B., Bryn Mawr College 1998

Contact

full name

Abigail Susan Haka

primary email

abh2005@med.cornell.edu

VIVO Weill Cornell Medical College

Abigail Susan Haka Adjunct Assistant Professor of Research in Biochemistry

Publications

selected publications

Background

education and training

Contact

full name

primary email