Weinstein, Alan M

Publications

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selected publications

High dietary K intake inhibits proximal tubule transport. American journal of physiology. Renal physiology. 2023 Academic Article GET IT
Regulation of glomerulotubular balance. IV. Implication of aquaporin 1 in flow-dependent proximal tubule transport and cell volume. American journal of physiology. Renal physiology. 2022 Academic Article GET IT
Assessing proteinuria: value added from a mathematical model. The Journal of physiology. 2022 Academic Article GET IT
A mathematical model of the rat kidney. IV. Whole kidney response to hyperkalemia. American journal of physiology. Renal physiology. 2022 Academic Article GET IT
Times cited: 4
Sex difference in kidney electrolyte transport III: Impact of low K intake on thiazide-sensitive cation excretion in male and female mice. Pflugers Archiv : European journal of physiology. 2021 Academic Article GET IT
Times cited: 5
ENaC and ROMK channels in the connecting tubule regulate renal K+ secretion. The Journal of general physiology. 2021 Academic Article GET IT
Times cited: 16
Restoration of proximal tubule flow-activated transport prevents cyst growth in polycystic kidney disease. JCI insight. 2021 Academic Article GET IT
Times cited: 3
A mathematical model of the rat kidney. III. Ammonia transport. American journal of physiology. Renal physiology. 2021 Academic Article GET IT
Times cited: 2
Social Determinants of Health in People with Kidney Disease: An Introduction. Clinical journal of the American Society of Nephrology : CJASN. 2021 Article GET IT
Times cited: 4
A mathematical model of the rat kidney. II. Antidiuresis. American journal of physiology. Renal physiology. 2020 Academic Article GET IT
Times cited: 5
Accurate measurement of fast endocytic recycling kinetics in real time. Journal of cell science. 2020 Academic Article GET IT
Times cited: 23
Sex difference in kidney electrolyte transport II: impact of K⁺ intake on thiazide-sensitive cation excretion in male and female mice. American journal of physiology. Renal physiology. 2019 Academic Article GET IT
Times cited: 13
By the way, proximal tubule calcium transport. American journal of physiology. Renal physiology. 2018 Editorial Article GET IT
Times cited: 1
Regulation of renal Na transporters in response to dietary K. American journal of physiology. Renal physiology. 2018 Academic Article GET IT
Times cited: 38
Gender difference in kidney electrolyte transport. I. Role of AT_1a receptor in thiazide-sensitive Na⁺-Cl^- cotransporter activity and expression in male and female mice. American journal of physiology. Renal physiology. 2017 Academic Article GET IT
Times cited: 17
Coping with nephron loss: transport at a price. American journal of physiology. Renal physiology. 2017 Editorial Article GET IT
Responses of distal nephron Na⁺ transporters to acute volume depletion and hyperkalemia. American journal of physiology. Renal physiology. 2017 Academic Article GET IT
Times cited: 20
Regulation of glomerulotubular balance: flow-activated proximal tubule function. Pflugers Archiv : European journal of physiology. 2017 Review GET IT
Times cited: 17
A mathematical model of the rat kidney: K⁺-induced natriuresis. American journal of physiology. Renal physiology. 2017 Academic Article GET IT
Times cited: 37
Systems biology of the cortical collecting duct. The Journal of physiology. 2016 Comment GET IT
Times cited: 1
The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells. Nature communications. 2016 Academic Article GET IT
Times cited: 56
Flow-activated proximal tubule function underlies glomerulotubular balance. The Kitasato medical journal. 2016 Academic Article GET IT
ENaC inhibition stimulates HCl secretion in the mouse cortical collecting duct. II. Bafilomycin-sensitive H+ secretion. American journal of physiology. Renal physiology. 2015 Academic Article GET IT
Times cited: 9
ENaC inhibition stimulates HCl secretion in the mouse cortical collecting duct. I. Stilbene-sensitive Cl- secretion. American journal of physiology. Renal physiology. 2015 Academic Article GET IT
Times cited: 9
A mathematical model of rat proximal tubule and loop of Henle. American journal of physiology. Renal physiology. 2015 Academic Article GET IT
Times cited: 29
A mathematical model of the rat nephron: glucose transport. American journal of physiology. Renal physiology. 2015 Academic Article GET IT
Times cited: 32
Regulation of glomerulotubular balance. III. Implication of cytosolic calcium in flow-dependent proximal tubule transport. American journal of physiology. Renal physiology. 2015 Academic Article GET IT
Times cited: 8
Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride. Cell metabolism. 2015 Academic Article GET IT
Times cited: 309
The diabetic proximal tubule: part of the problem, and part of the solution?. American journal of physiology. Renal physiology. 2014 Editorial Article GET IT
Times cited: 1
Relation between BK-α/β4-mediated potassium secretion and ENaC-mediated sodium reabsorption. Kidney international. 2014 Academic Article GET IT
Times cited: 19
Cortical distal nephron Cl(-) transport in volume homeostasis and blood pressure regulation. American journal of physiology. Renal physiology. 2013 Review GET IT
Times cited: 47
Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis. American journal of physiology. Cell physiology. 2013 Academic Article GET IT
Times cited: 26
Identifying renal medullary neighborhoods--when do distances matter?. American journal of physiology. Renal physiology. 2013 Editorial Article GET IT
Times cited: 4
Regulation of glomerulotubular balance: II: impact of angiotensin II on flow-dependent transport. American journal of physiology. Renal physiology. 2012 Academic Article GET IT
Times cited: 16
Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport. American journal of physiology. Renal physiology. 2012 Academic Article GET IT
Times cited: 16
ENaC inhibition stimulates Cl- secretion in the mouse cortical collecting duct through an NKCC1-dependent mechanism. American journal of physiology. Renal physiology. 2012 Academic Article GET IT
Times cited: 25
Potassium excretion during antinatriuresis: perspective from a distal nephron model. American journal of physiology. Renal physiology. 2011 Academic Article GET IT
Times cited: 20
Severe hyperosmolarity and hypernatremia in an adipsic young woman. 2011 GET IT
Times cited: 11
Potassium deprivation: a systems approach. American journal of physiology. Renal physiology. 2011 Editorial Article GET IT
Times cited: 1
Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells. Proceedings of the National Academy of Sciences of the United States of America. 2010 Academic Article GET IT
Times cited: 72
Pendrin modulates ENaC function by changing luminal HCO3-. Journal of the American Society of Nephrology : JASN. 2010 Academic Article GET IT
Times cited: 84
Mechanotransduction in the renal tubule. American journal of physiology. Renal physiology. 2010 Review GET IT
Times cited: 111
A mathematical model of rat ascending Henle limb. I. Cotransporter function. American journal of physiology. Renal physiology. 2009 Academic Article GET IT
Times cited: 23
A mathematical model of rat ascending Henle limb. II. Epithelial function. American journal of physiology. Renal physiology. 2009 Editorial Article GET IT
Times cited: 33
A mathematical model of rat ascending Henle limb. III. Tubular function. American journal of physiology. Renal physiology. 2009 Academic Article GET IT
Times cited: 29
Modeling proximal tubule cell homeostasis: tracking changes in luminal flow. Bulletin of mathematical biology. 2009 Academic Article GET IT
Times cited: 11
A mathematical model of distal nephron acidification: diuretic effects. American journal of physiology. Renal physiology. 2008 Academic Article GET IT
Times cited: 24
Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes. Proceedings of the National Academy of Sciences of the United States of America. 2008 Academic Article GET IT
Times cited: 134
Flow-dependent transport in a mathematical model of rat proximal tubule. American journal of physiology. Renal physiology. 2007 Academic Article GET IT
Times cited: 58
Angiotensin II increases chloride absorption in the cortical collecting duct in mice through a pendrin-dependent mechanism. American journal of physiology. Renal physiology. 2006 Academic Article GET IT
Times cited: 95
Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments. American journal of physiology. Renal physiology. 2005 Academic Article GET IT
Times cited: 76
A mathematical model of rat distal convoluted tubule. I. Cotransporter function in early DCT. American journal of physiology. Renal physiology. 2005 Academic Article GET IT
Times cited: 64
A mathematical model of rat distal convoluted tubule. II. Potassium secretion along the connecting segment. American journal of physiology. Renal physiology. 2005 Academic Article GET IT
Times cited: 53
Modeling epithelial cell homeostasis: assessing recovery and control mechanisms. Bulletin of mathematical biology. 2004 Academic Article GET IT
Times cited: 10
Mechanosensory function of microvilli of the kidney proximal tubule. Proceedings of the National Academy of Sciences of the United States of America. 2004 Academic Article GET IT
Times cited: 99
Activation of the apical Na+/H+ exchanger NHE3 by formate: a basis of enhanced fluid and electrolyte reabsorption by formate in the kidney. American journal of physiology. Renal physiology. 2004 Academic Article GET IT
Times cited: 16
Mathematical models of renal fluid and electrolyte transport: acknowledging our uncertainty. American journal of physiology. Renal physiology. 2003 Review GET IT
Times cited: 32
A dual-pathway ultrastructural model for the tight junction of rat proximal tubule epithelium. American journal of physiology. Renal physiology. 2003 Academic Article GET IT
Times cited: 38
A mathematical model of rat collecting duct. I. Flow effects on transport and urinary acidification. American journal of physiology. Renal physiology. 2002 Academic Article GET IT
Times cited: 33
A mathematical model of rat collecting duct. II. Effect of buffer delivery on urinary acidification. American journal of physiology. Renal physiology. 2002 Academic Article GET IT
Times cited: 7
A mathematical model of rat collecting duct. III. Paradigms for distal acidification defects. American journal of physiology. Renal physiology. 2002 Academic Article GET IT
Times cited: 12
New roles for old holes: ion channel function in aquaporin-1. News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society. 2002 Review GET IT
Times cited: 94
The paracellular shunt of proximal tubule. The Journal of membrane biology. 2002 Review GET IT
Times cited: 9
A mathematical model of rat cortical collecting duct: determinants of the transtubular potassium gradient. American journal of physiology. Renal physiology. 2001 Academic Article GET IT
Times cited: 46
A hydrodynamic mechanosensory hypothesis for brush border microvilli. American journal of physiology. Renal physiology. 2000 Academic Article GET IT
Times cited: 156
A mathematical model of the outer medullary collecting duct of the rat. American journal of physiology. Renal physiology. 2000 Academic Article GET IT
Times cited: 42
Modeling epithelial cell homeostasis: steady-state analysis. Bulletin of mathematical biology. 1999 Academic Article GET IT
Times cited: 18
Water does not flow across the tight junctions of MDCK cell epithelium. Proceedings of the National Academy of Sciences of the United States of America. 1998 Academic Article GET IT
Times cited: 79
A mathematical model of the inner medullary collecting duct of the rat: acid/base transport. The American journal of physiology. 1998 Academic Article GET IT
Times cited: 18
A mathematical model of the inner medullary collecting duct of the rat: pathways for Na and K transport. The American journal of physiology. 1998 Academic Article GET IT
Times cited: 55
Insights from mathematical modeling of renal tubular function. Experimental nephrology. 1998 Review GET IT
Times cited: 8
Dynamics of cellular homeostasis: recovery time for a perturbation from equilibrium. Bulletin of mathematical biology. 1997 Academic Article GET IT
Times cited: 11
Coupling of entry to exit by peritubular K+ permeability in a mathematical model of rat proximal tubule. The American journal of physiology. 1996 Academic Article GET IT
Times cited: 15
Acid/base transport in a model of the proximal tubule brush border: impact of carbonic anhydrase. The American journal of physiology. 1996 Academic Article GET IT
Times cited: 25
A kinetically defined Na+/H+ antiporter within a mathematical model of the rat proximal tubule. The Journal of general physiology. 1995 Academic Article GET IT
Times cited: 36
Ammonia transport in a mathematical model of rat proximal tubule. The American journal of physiology. 1994 Academic Article GET IT
Times cited: 16
Weak acid permeability of a villous membrane: formic acid transport across rat proximal tubule. Bulletin of mathematical biology. 1994 Academic Article GET IT
Times cited: 14
Mathematical models of tubular transport. Annual review of physiology. 1994 Review GET IT
Times cited: 30
A mathematical model of the rabbit cortical collecting tubule. The American journal of physiology. 1992 Academic Article GET IT
Times cited: 30
Regulation of K transport in a mathematical model of the cortical collecting tubule. The American journal of physiology. 1992 Academic Article GET IT
Times cited: 19
Chloride transport in a mathematical model of the rat proximal tubule. The American journal of physiology. 1992 Academic Article GET IT
Times cited: 37
Analysis of volume regulation in an epithelial cell model. Bulletin of mathematical biology. 1992 Academic Article GET IT
Times cited: 9
Coupled water transport by rat proximal tubule. The American journal of physiology. 1991 Academic Article GET IT
Times cited: 34
The effect of low-energy combined AC and DC magnetic fields on articular cartilage metabolism. Annals of the New York Academy of Sciences. 1991 Academic Article GET IT
Times cited: 17
Volume-activated chloride permeability can mediate cell volume regulation in a mathematical model of a tight epithelium. The Journal of general physiology. 1990 Academic Article GET IT
Times cited: 37
Glomerulotubular balance in a mathematical model of the proximal nephron. The American journal of physiology. 1990 Academic Article GET IT
Times cited: 21
Osmotic water permeability of Necturus gallbladder epithelium. The Journal of general physiology. 1989 Academic Article GET IT
Times cited: 39
An elective course for first-year students based on the New England Journal of Medicine. Journal of medical education. 1988 Academic Article GET IT
Times cited: 1
Modeling the proximal tubule: complications of the paracellular pathway. The American journal of physiology. 1988 Review GET IT
Times cited: 35
Convective paracellular solute flux. A source of ion-ion interaction in the epithelial transport equations. The Journal of general physiology. 1987 Academic Article GET IT
Times cited: 28
The regulation of cytosolic calcium in rat brain synaptosomes by sodium-dependent calcium efflux. The Journal of physiology. 1986 Academic Article GET IT
Times cited: 64
A mathematical model of the rat proximal tubule. The American journal of physiology. 1986 Academic Article GET IT
Times cited: 24
Osmotic diuresis in a mathematical model of the rat proximal tubule. The American journal of physiology. 1986 Academic Article GET IT
Times cited: 36
An equation for flow in the renal proximal tubule. Bulletin of mathematical biology. 1986 Academic Article GET IT
Times cited: 8
Glucose transport in a model of the rat proximal tubule epithelium. Annals of the New York Academy of Sciences. 1985 Academic Article GET IT
Transport by epithelia with compliant lateral intercellular spaces: asymmetric oncotic effects across the rat proximal tubule. The American journal of physiology. 1984 Academic Article GET IT
Times cited: 18
The overshoot phenomenon in cotransport. Biochimica et biophysica acta. 1984 Academic Article GET IT
Times cited: 35
Single-needle venous dialysis: a comparison of three systems. Uremia investigation. 1984 Academic Article GET IT
Nonequilibrium thermodynamic model of the rat proximal tubule epithelium. Biophysical journal. 1983 Academic Article GET IT
Times cited: 31
Prognostic patterns in acute renal failure: the New York Hospital, 1981-1982. Clinical and experimental dialysis and apheresis. 1983 Academic Article GET IT
Times cited: 17
Coupled water transport in standing gradient models of the lateral intercellular space. Biophysical journal. 1981 Academic Article GET IT
Times cited: 23
Models of coupled salt and water transport across leaky epithelia. The Journal of membrane biology. 1981 Academic Article GET IT
Times cited: 46
Carbon dioxide permeability of rabbit proximal convoluted tubules. The American journal of physiology. 1981 Academic Article GET IT
Times cited: 23
Electrolyte transport across a simple epithelium. Steady-state and transient analysis. Biophysical journal. 1979 Academic Article GET IT
Times cited: 31

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Research

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Funding awarded

Theory of Solute and Water Transport Across Epithelia awarded by National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator 2018 - 2024

Defective flow-dependent tubule transport in the pathogenesis of kidney disease awarded by National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator Subaward 2019 - 2023

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Background

education and training

M.D., Harvard Medical School 1975
A.B., Princeton University 1971

Contact

full name

Alan M Weinstein

primary email

amweins@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Alan M Weinstein Professor of Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage