selected publications
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Sphingosine-1-phosphate controls endothelial sphingolipid homeostasis via ORMDL.
EMBO reports.
2022
Academic Article
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Times cited: 3 -
Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301.
Human molecular genetics.
2022
Review
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Times cited: 1 -
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
Cell.
2022
Academic Article
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Times cited: 49 -
Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes.
Autophagy.
2021
Academic Article
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Times cited: 13 -
Better understanding the neurobiology of primary lateral sclerosis.
Amyotrophic lateral sclerosis & frontotemporal degeneration.
2020
Review
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Times cited: 2 -
Accelerated transsulfuration metabolically defines a discrete subclass of amyotrophic lateral sclerosis patients.
Neurobiology of disease.
2020
Academic Article
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Times cited: 9 -
Prohibitin S-Nitrosylation Is Required for the Neuroprotective Effect of Nitric Oxide in Neuronal Cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2020
Academic Article
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Times cited: 11 -
Nrf2 signaling links ER oxidative protein folding and calcium homeostasis in health and disease.
Life science alliance.
2019
Academic Article
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Times cited: 19 -
Redox-Dependent Loss of Flavin by Mitochondrial Complex I in Brain Ischemia/Reperfusion Injury.
Antioxidants & redox signaling.
2019
Academic Article
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Times cited: 34 -
Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs.
Cell stem cell.
2019
Academic Article
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Times cited: 65 -
The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A.
Journal of neurochemistry.
2019
Academic Article
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Times cited: 25 -
IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity.
Nature.
2018
Academic Article
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Times cited: 205 -
Parkin is a disease modifier in the mutant SOD1 mouse model of ALS.
EMBO molecular medicine.
2018
Academic Article
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Times cited: 43 -
Critical Role of Flavin and Glutathione in Complex I-Mediated Bioenergetic Failure in Brain Ischemia/Reperfusion Injury.
Stroke.
2018
Academic Article
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Times cited: 57 -
Deactivation of mitochondrial complex I after hypoxia-ischemia in the immature brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2018
Academic Article
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Times cited: 18 -
Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.
Molecular neurodegeneration.
2017
Academic Article
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Times cited: 37 -
Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia reperfusion injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2017
Academic Article
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Times cited: 42 -
Distinct intracellular sAC-cAMP domains regulate ER Ca2+ signaling and OXPHOS function.
Journal of cell science.
2017
Academic Article
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Times cited: 21 -
Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo.
Molecular neurodegeneration.
2017
Academic Article
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Times cited: 29 -
Divalent cation chelators citrate and EDTA unmask an intrinsic uncoupling pathway in isolated mitochondria.
Journal of bioenergetics and biomembranes.
2016
Academic Article
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Times cited: 4 -
Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.
Nature medicine.
2016
Academic Article
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Times cited: 163 -
Role of soluble adenylyl cyclase in mitochondria.
Biochimica et biophysica acta.
2014
Review
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Times cited: 43 -
Mitochondrial diaphorases as NAD⁺ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2014
Academic Article
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Times cited: 29 -
The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2013
Academic Article
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Times cited: 43 -
Absence of Ca2+-induced mitochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in C. crangon and P. serratus.
PloS one.
2012
Academic Article
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Times cited: 13 -
Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels.
The FEBS journal.
2011
Academic Article
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Times cited: 38 -
A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration.
The FEBS journal.
2011
Academic Article
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Times cited: 15 -
Complex contribution of cyclophilin D to Ca2+-induced permeability transition in brain mitochondria, with relation to the bioenergetic state.
The Journal of biological chemistry.
2010
Academic Article
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Times cited: 28 -
Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level phosphorylation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2010
Academic Article
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Times cited: 75 -
A re-evaluation of the role of matrix acidification in uncoupler-induced Ca2+ release from mitochondria.
The FEBS journal.
2009
Academic Article
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Times cited: 14