Redmond, David

Publications

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selected publications

MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence. Clinical and experimental immunology. 2023 Academic Article GET IT
Profiling Germinal Center-like B Cell Responses to Conjugate Vaccines Using Synthetic Immune Organoids. ACS central science. 2023 Academic Article GET IT
Times cited: 44
Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response. Nature communications. 2023 Academic Article GET IT
T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants. Cell. 2023 Academic Article GET IT
Times cited: 3
Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing. bioRxiv : the preprint server for biology. 2023 Article GET IT
Defibrotide mitigates endothelial cell injury induced by plasmas from patients with COVID-19 and related vasculopathies. Thrombosis research. 2023 Academic Article GET IT
Times cited: 1
Systems Biology Analysis of Temporal Dynamics That Govern Endothelial Response to Cyclic Stretch. Biomolecules. 2022 Review GET IT
Cooperative ETS Transcription Factors Enforce Adult Endothelial Cell Fate and Cardiovascular Homeostasis. Nature cardiovascular research. 2022 Academic Article GET IT
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine. Science translational medicine. 2022 Academic Article GET IT
Times cited: 5
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions. The Journal of experimental medicine. 2022 Academic Article GET IT
Times cited: 3
Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/- trastuzumab in patients with breast cancer brain metastases. NPJ breast cancer. 2022 Academic Article GET IT
Times cited: 104
Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy. iScience. 2022 Academic Article GET IT
Times cited: 19
Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. Cell stem cell. 2022 Academic Article GET IT
Times cited: 12
Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice. Scientific reports. 2022 Academic Article GET IT
Times cited: 2
Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection. JCI insight. 2022 Review GET IT
Times cited: 35
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2. Cell metabolism. 2021 Article GET IT
Times cited: 11
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2. Stem cell reports. 2021 Article GET IT
Times cited: 3
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell stem cell. 2021 Academic Article GET IT
Times cited: 9
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2. Cell metabolism. 2021 Academic Article GET IT
Times cited: 86
Reversal of emphysema by restoration of pulmonary endothelial cells. The Journal of experimental medicine. 2021 Academic Article GET IT
Times cited: 20
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2. Stem cell reports. 2021 Academic Article GET IT
Times cited: 26
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts. Circulation research. 2021 Academic Article GET IT
Times cited: 25
Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells: Current Controversies. Frontiers in physiology. 2021 Academic Article GET IT
Times cited: 2388
Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice. Communications biology. 2021 Academic Article GET IT
Times cited: 4
Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate. Proceedings of the National Academy of Sciences of the United States of America. 2021 Academic Article GET IT
Times cited: 84
SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2. Research square. 2020 Article GET IT
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2020 Academic Article GET IT
Times cited: 274
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis. Nature. 2020 Academic Article GET IT
Times cited: 102
Mutation landscape, clonal evolution pattern, and potential pathogenic pathways in B-lymphoblastic transformation of follicular lymphoma. Leukemia. 2020 Letter GET IT
Times cited: 6
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine. Nature communications. 2020 Academic Article GET IT
Times cited: 131
Comparison of Human Antral Follicles of Xenograft versus Ovarian Origin Reveals Disparate Molecular Signatures. Cell reports. 2020 Academic Article GET IT
Times cited: 16
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids. Cell stem cell. 2020 Academic Article GET IT
Times cited: 420
Endothelial deletion of ADAM10, a key regulator of Notch signaling, causes impaired decidualization and reduced fertility in female mice. Angiogenesis. 2020 Academic Article GET IT
Times cited: 13
Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids. bioRxiv : the preprint server for biology. 2020 Article GET IT
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes. Nature communications. 2020 Academic Article GET IT
Times cited: 20
ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity. Nature. 2020 Academic Article GET IT
Times cited: 188
Molecular determinants of nephron vascular specialization in the kidney. Nature communications. 2019 Academic Article GET IT
Times cited: 48
Exploring tumor clonal evolution in bone marrow of patients with diffuse large B-cell lymphoma by deep IGH sequencing and its potential relevance in relapse. Blood cancer journal. 2019 Letter GET IT
Times cited: 2
In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors. The Journal of clinical investigation. 2019 Academic Article GET IT
Times cited: 28
Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer. Cell reports. 2019 Academic Article GET IT
Times cited: 36
Association of T-Cell Receptor Repertoire Use With Response to Combined Trastuzumab-Lapatinib Treatment of HER2-Positive Breast Cancer: Secondary Analysis of the NeoALTTO Randomized Clinical Trial. JAMA oncology. 2018 Academic Article GET IT
Times cited: 12
AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis. Nature communications. 2018 Academic Article GET IT
Times cited: 42
Wnt inhibition promotes vascular specification of embryonic cardiac progenitors. Development (Cambridge, England). 2018 Academic Article GET IT
Times cited: 6
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop. Nature communications. 2017 Academic Article GET IT
Times cited: 109
Conversion of adult endothelium to immunocompetent haematopoietic stem cells. Nature. 2017 Academic Article GET IT
Times cited: 144
Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy. Cancer immunology research. 2016 Academic Article GET IT
Times cited: 104
Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq. Genome medicine. 2016 Academic Article GET IT
Times cited: 81
VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma. Journal of visualized experiments : JoVE. 2015 Academic Article GET IT
Times cited: 13
EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis. Leukemia. 2015 Academic Article GET IT
Times cited: 49
DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID. Cell reports. 2015 Academic Article GET IT
Times cited: 77
Epigenomic evolution in diffuse large B-cell lymphomas. Nature communications. 2015 Academic Article GET IT
Times cited: 95
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas. Genome biology. 2014 Academic Article GET IT
Times cited: 74

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Research

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Co-investigator Network

Funding awarded

Adaptable tissue-specific endothelial cells for organ regeneration awarded by National Heart, Lung, & Blood Institute Co-Investigator 2020 - 2027
Weill Cornell Medicine (WCM) SPORE in Prostate Cancer awarded by National Cancer Institute Co-Investigator 2017 - 2023

Derivation of pancreatic islet-like organoids from human gastric stem cells awarded by National Institute of Diabetes & Digestive & Kidney Diseases Key Personnel 2022 - 2026
Assessing the effects of peripheral immune activation on the NVU following TBI using a vascularized and perfused human blood/BBB model awarded by National Institute of Environmental Health Sciences Key Personnel 2021 - 2023

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Background

education and training

Ph.D., Weill Cornell Medical College, Cornell University 2017
M.Sc., Oxford University (United Kingdom) 2003
B.A., Cambridge University (United Kingdom) 2002

Contact

full name

David Redmond

primary email

dar2042@med.cornell.edu

VIVO Weill Cornell Medical College

David Redmond Assistant Professor of Computational Biology Research in Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email