selected publications
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Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
Nature genetics.
2022
Academic Article
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Times cited: 17 -
Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancer.
Cell death & disease.
2022
Academic Article
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Times cited: 1 -
Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction.
Cell stem cell.
2022
Academic Article
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Times cited: 12 -
A BAX door to venetoclax resistance.
Blood.
2022
Editorial Article
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Times cited: 3 -
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.
Nature genetics.
2021
Academic Article
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Times cited: 53 -
Canonical ErbB-2 isoform and ErbB-2 variant c located in the nucleus drive triple negative breast cancer growth.
Oncogene.
2020
Academic Article
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Times cited: 4 -
Nuclear PDCD4 Expression Defines a Subset of Luminal B-Like Breast Cancers with Good Prognosis.
Hormones & cancer.
2020
Academic Article
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Times cited: 7 -
Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells.
Cell reports.
2020
Academic Article
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Times cited: 20 -
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Nature genetics.
2020
Academic Article
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Times cited: 101 -
Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.
Cell reports.
2020
Academic Article
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Times cited: 51 -
EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation.
Genome biology.
2019
Academic Article
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Times cited: 22 -
m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.
Cell reports.
2019
Academic Article
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Times cited: 86 -
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nature.
2019
Academic Article
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Times cited: 129 -
Genetic and epigenetic determinants of B-cell lymphoma evolution.
Current opinion in hematology.
2016
Review
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Times cited: 3 -
MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1.
Oncogene.
2016
Academic Article
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Times cited: 62 -
Heregulin Co-opts PR Transcriptional Action Via Stat3 Role As a Coregulator to Drive Cancer Growth.
Molecular endocrinology (Baltimore, Md.).
2015
Academic Article
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Times cited: 12 -
Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis.
Oncogene.
2015
Academic Article
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Times cited: 51 -
Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth.
Breast cancer research : BCR.
2014
Academic Article
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Times cited: 25 -
Progestin drives breast cancer growth by inducing p21(CIP1) expression through the assembly of a transcriptional complex among Stat3, progesterone receptor and ErbB-2.
Steroids.
2012
Academic Article
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Times cited: 25