Kelly, James

Publications

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selected publications

Cystine rather than cysteine is the preferred substrate for β-elimination by cystathionine γ-lyase: implications for dietary methionine restriction. GeroScience. 2023 Academic Article GET IT
In vivo Brain Estrogen Receptor Expression By Neuroendocrine Aging And Relationships With Gray Matter Volume, Bio-Energetics, and Clinical Symptomatology. Research square. 2023 Article GET IT
Times cited: 25
Stabilization of guinea pig transglutaminase 2 solutions. Analytical biochemistry. 2022 Academic Article GET IT
Advances in PSMA theranostics. Translational oncology. 2022 Academic Article GET IT
Times cited: 27
Synthesis and Evaluation of ¹¹C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography. Molecules (Basel, Switzerland). 2022 Academic Article GET IT
PET Tracers for Imaging Cardiac Function in Cardio-oncology. Current cardiology reports. 2022 Review GET IT
Times cited: 5
A suitable time point for quantifying the radiochemical purity of ²²⁵Ac-labeled radiopharmaceuticals. EJNMMI radiopharmacy and chemistry. 2021 Academic Article GET IT
Times cited: 304
A Trifunctional Theranostic Ligand Targeting Fibroblast Activation Protein-α (FAPα). Molecular imaging and biology. 2021 Academic Article GET IT
Times cited: 10
Preclinical Evaluation of a High-Affinity Sarcophagine-Containing PSMA Ligand for ⁶⁴Cu/⁶⁷Cu-Based Theranostics in Prostate Cancer. Molecular pharmaceutics. 2020 Academic Article GET IT
Times cited: 19
3D-printed automation for optimized PET radiochemistry. Science advances. 2019 Academic Article GET IT
Times cited: 5
PET Neuroimaging Reveals Serotonergic and Metabolic Dysfunctions in the Hippocampal Electrical Kindling Model of Epileptogenesis. Neuroscience. 2019 Academic Article GET IT
Times cited: 7
[¹⁸F]Fluoroethyltriazolyl Monocyclam Derivatives as Imaging Probes for the Chemokine Receptor CXCR4. Molecules (Basel, Switzerland). 2019 Academic Article GET IT
Times cited: 6
Albumin-Binding PSMA Ligands: Implications for Expanding the Therapeutic Window. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 33
A Single Dose of ²²⁵Ac-RPS-074 Induces a Complete Tumor Response in an LNCaP Xenograft Model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 45
⁶⁶Ga: A Novelty or a Valuable Preclinical Screening Tool for the Design of Targeted Radiopharmaceuticals?. Molecules (Basel, Switzerland). 2018 Academic Article GET IT
Times cited: 8
Trifunctional PSMA-targeting constructs for prostate cancer with unprecedented localization to LNCaP tumors. European journal of nuclear medicine and molecular imaging. 2018 Academic Article GET IT
Times cited: 48
[¹⁸F]RPS-544: A PET tracer for imaging the chemokine receptor CXCR4. Nuclear medicine and biology. 2018 Academic Article GET IT
Times cited: 10
An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angewandte Chemie (International ed. in English). 2017 Academic Article GET IT
Times cited: 117
Assessment of PSMA targeting ligands bearing novel chelates with application to theranostics: Stability and complexation kinetics of ⁶⁸Ga³⁺, ¹¹¹In³⁺, ¹⁷⁷Lu³⁺ and ²²⁵Ac³. Nuclear medicine and biology. 2017 Academic Article GET IT
Times cited: 19
Continuation of comprehensive quality control of the itG ⁶⁸Ge/⁶⁸Ga generator and production of ⁶⁸Ga-DOTATOC and ⁶⁸Ga-PSMA-HBED-CC for clinical research studies. Nuclear medicine and biology. 2017 Academic Article GET IT
Times cited: 6
Dual-Target Binding Ligands with Modulated Pharmacokinetics for Endoradiotherapy of Prostate Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 56
Synthesis and pre-clinical evaluation of a new class of high-affinity ¹⁸F-labeled PSMA ligands for detection of prostate cancer by PET imaging. European journal of nuclear medicine and molecular imaging. 2016 Academic Article GET IT
Times cited: 43
Preliminary research on 1-(4-bromo-2-nitroimidazol-1-yl)-3-[(18)F]fluoropropan-2-ol as a novel brain hypoxia PET tracer in a rodent model of stroke. European journal of medicinal chemistry. 2015 Academic Article GET IT
Times cited: 8
Synthesis of [11C]palmitic acid for PET imaging using a single molecular sieve 13X cartridge for reagent trapping, radiolabeling and selective purification. Nuclear medicine and biology. 2015 Academic Article GET IT
Times cited: 6
N-(4-[(18)F]-fluoropyridin-2-yl)-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}carboxamides as analogs of WAY100635. New PET tracers of serotonin 5-HT(1A) receptors. European journal of medicinal chemistry. 2014 Academic Article GET IT
Times cited: 6

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Research

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Co-investigator Network

Funding awarded

Investigating PK modulation in targeted radiotherapy awarded by Ratio Therapeutics, LLC Principal Investigator 2022 - 2024
The Development of Radiolabeled Positional isomers of [11C]Pyruvate for Imaging Cancer Metabolism awarded by National Institute of Biomedical Imaging & Bioengineering Principal Investigator 2020 - 2024

Clinical and Translational Science Center- Institutional CTSC Internal Funding UL1 awarded by CTSC Cost Share Co-Investigator 2022 - 2027
CSF Clearance in Sporadic Alzheimer''s Disease awarded by National Institute on Aging Co-Investigator 2019 - 2024
Targeting lipid metabolism and diet in patients with locally advanced prostate cancer awarded by Prostate Cancer Foundation Co-Investigator 2023 - 2023

New PET/CT System for Human and Non-human Primate Imaging awarded by National Institutes of Health, Office of the Director Key Personnel 2023 - 2024
Major Cyclotron Upgrades and Refurbishment awarded by National Institutes of Health, Office of the Director Key Personnel 2021 - 2023

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Background

education and training

Ph.D., University of Cambridge (United Kingdom) 2011
A.B., Harvard University 2006

Contact

full name

James Kelly

primary email

jak2046@med.cornell.edu

VIVO Weill Cornell Medical College

James Kelly Assistant Professor of Radiopharmaceutical Sciences in Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email