Wagner, John A.

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selected publications

Correction: Calcitonin Gene-Related Peptide-Exposed Endothelial Cells Bias Antigen Presentation to CD4+ T Cells toward a Th17 Response. Journal of immunology (Baltimore, Md. : 1950). 2023 Article GET IT
Regulation of T helper cell responses during antigen presentation by norepinephrine-exposed endothelial cells. Immunology. 2017 Academic Article GET IT
Times cited: 6
Calcitonin Gene-Related Peptide-Exposed Endothelial Cells Bias Antigen Presentation to CD4+ T Cells toward a Th17 Response. Journal of immunology (Baltimore, Md. : 1950). 2016 Academic Article GET IT
Times cited: 25
Calcitonin gene-related peptide: key regulator of cutaneous immunity. Acta physiologica (Oxford, England). 2015 Review GET IT
Times cited: 53
Equivalent dynamic human brain NK1-receptor occupancy following single-dose i.v. fosaprepitant vs. oral aprepitant as assessed by PET imaging. Clinical pharmacology and therapeutics. 2012 Academic Article GET IT
Times cited: 39
Pituitary adenylate cyclase-activating peptide and vasoactive intestinal polypeptide bias Langerhans cell Ag presentation toward Th17 cells. European journal of immunology. 2012 Academic Article GET IT
Times cited: 27
Retinoids regulate stem cell differentiation. Journal of cellular physiology. 2011 Review GET IT
Times cited: 292
Calcitonin gene-related peptide biases Langerhans cells toward Th2-type immunity. Journal of immunology (Baltimore, Md. : 1950). 2008 Academic Article GET IT
Times cited: 97
Tetracycline suppresses ATP gamma S-induced CXCL8 and CXCL1 production by the human dermal microvascular endothelial cell-1 (HMEC-1) cell line and primary human dermal microvascular endothelial cells. Experimental dermatology. 2008 Academic Article GET IT
Times cited: 27
Norepinephrine modulates human dendritic cell activation by altering cytokine release. Experimental dermatology. 2008 Academic Article GET IT
Times cited: 57
"Soluble" adenylyl cyclase-generated cyclic adenosine monophosphate promotes fast migration in PC12 cells. Journal of neuroscience research. 2008 Academic Article GET IT
Times cited: 13
CGRP, PACAP, and VIP modulate Langerhans cell function by inhibiting NF-kappaB activation. The Journal of investigative dermatology. 2007 Academic Article GET IT
Times cited: 55
Requirement for Akt-mediated survival in cell transformation by the dbl oncogene. Cellular signalling. 2006 Academic Article GET IT
Times cited: 8
ATPgammaS enhances the production of inflammatory mediators by a human dermal endothelial cell line via purinergic receptor signaling. The Journal of investigative dermatology. 2006 Academic Article GET IT
Times cited: 54
Augmentation of cutaneous immune responses by ATP gamma S: purinergic agonists define a novel class of immunologic adjuvants. Journal of immunology (Baltimore, Md. : 1950). 2005 Academic Article GET IT
Times cited: 56
Vasoactive intestinal peptide modulates Langerhans cell immune function. Journal of immunology (Baltimore, Md. : 1950). 2004 Academic Article GET IT
Times cited: 47
Pituitary adenylate cyclase-activating polypeptide inhibits cutaneous immune function. European journal of immunology. 2003 Academic Article GET IT
Times cited: 25
Catecholamines inhibit the antigen-presenting capability of epidermal Langerhans cells. Journal of immunology (Baltimore, Md. : 1950). 2002 Academic Article GET IT
Times cited: 113
HES-1 repression of differentiation and proliferation in PC12 cells: role for the helix 3-helix 4 domain in transcription repression. Molecular and cellular biology. 2000 Academic Article GET IT
Times cited: 92
Regulation of NGFI-A (Egr-1) gene expression by the POU domain transcription factor Brn-3a. Brain research. Molecular brain research. 1999 Academic Article GET IT
Times cited: 5
Regulation of hippocampal neuronal differentiation by the basic helix-loop-helix transcription factors HES-1 and MASH-1. Journal of neuroscience research. 1999 Academic Article GET IT
Times cited: 56
Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein. Molecular and cellular biology. 1998 Academic Article GET IT
Times cited: 67
Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation. Genes & development. 1997 Academic Article GET IT
Times cited: 95
Regulation of the neural-specific gene VGF in PC12 cells. Identification of transcription factors interacting with NGF-responsive elements. Journal of molecular neuroscience : MN. 1997 Academic Article GET IT
Times cited: 14
Rac is required for growth cone function but not neurite assembly. Journal of cell science. 1997 Academic Article GET IT
Times cited: 72
Unusual expression of the Hu paraneoplastic antigen in the visual system. Neuroreport. 1996 Academic Article GET IT
Times cited: 11
Is IL-6 both a cytokine and a neurotrophic factor?. The Journal of experimental medicine. 1996 Comment GET IT
Times cited: 60
Src, ras, and rac mediate the migratory response elicited by NGF and PMA in PC12 cells. Journal of neuroscience research. 1996 Academic Article GET IT
Times cited: 45
The role of signal transduction systems in mediating cell density dependent changes in tyrosine hydroxylase gene expression. Brain research. Molecular brain research. 1995 Academic Article GET IT
Times cited: 13
Expression of the choline acetyltransferase gene depends on protein kinase A activity. Journal of neurochemistry. 1995 Academic Article GET IT
Times cited: 30
Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. International journal of cancer. 1995 Academic Article GET IT
Times cited: 237
NGF protects PC12 cells against ischemia by a mechanism that requires the N-kinase. Journal of neuroscience research. 1995 Academic Article GET IT
Times cited: 25
Expression of the neural form of nitric oxide synthase by CA1 hippocampal neurons and other central nervous system neurons. Neuroscience. 1994 Academic Article GET IT
Times cited: 95
The cAMP-dependent protein kinase regulates transcription of the dopamine beta-hydroxylase gene. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1994 Academic Article GET IT
Times cited: 46
Transcriptional regulation of secretogranin II and chromogranin B by cyclic AMP in a rat pheochromocytoma cell line. Molecular pharmacology. 1994 Academic Article GET IT
Times cited: 17
Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia. Brain research. 1994 Academic Article GET IT
Times cited: 300
Optic nerve injury alters basic fibroblast growth factor localization in the retina and optic tract. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1994 Academic Article GET IT
Times cited: 104
Transient global ischemia induces dynamic changes in the expression of bFGF and the FGF receptor. Brain research. Molecular brain research. 1994 Academic Article GET IT
Times cited: 84
Nitric oxide: a downstream mediator of calcium toxicity in the ischemic cascade. Neuroscience letters. 1994 Academic Article GET IT
Times cited: 47
Growth factors protect PC12 cells against ischemia by a mechanism that is independent of PKA, PKC, and protein synthesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1993 Academic Article GET IT
Times cited: 67
Protein kinases modulate the sensitivity of hippocampal neurons to nitric oxide toxicity and anoxia. Journal of neuroscience research. 1993 Academic Article GET IT
Times cited: 72
NGFIA (EGR1) contains transcription activating domains in both the amino terminal and carboxyl terminal regions of the protein. Biochemical and biophysical research communications. 1993 Academic Article GET IT
Times cited: 6
Peptide growth factors protect against ischemia in culture by preventing nitric oxide toxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1993 Academic Article GET IT
Times cited: 154
Reactive astrocytes express NADPH diaphorase in vivo after transient ischemia. Neuroscience letters. 1993 Academic Article GET IT
Times cited: 69
A dual role for the cAMP-dependent protein kinase in tyrosine hydroxylase gene expression. Proceedings of the National Academy of Sciences of the United States of America. 1993 Academic Article GET IT
Times cited: 96
Nerve growth factor induces transcription of NGFIA through complex regulatory elements that are also sensitive to serum and phorbol 12-myristate 13-acetate. Molecular endocrinology (Baltimore, Md.). 1993 Academic Article GET IT
Times cited: 50
Retinoic acid regulates both expression of the nerve growth factor receptor and sensitivity to nerve growth factor. The Journal of biological chemistry. 1992 Academic Article GET IT
Times cited: 58
Activation of protein kinase A is necessary but not sufficient for ethanol-induced desensitization of cyclic AMP production. The Journal of pharmacology and experimental therapeutics. 1992 Academic Article GET IT
Times cited: 28
NGF induces the expression of the VGF gene through a cAMP response element. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1992 Academic Article GET IT
Times cited: 69
Rapid fibroblast growth factor-induced increases in protein phosphorylation and ornithine decarboxylase activity: regulation by heparin and comparison to nerve growth factor-induced increases. Experimental cell research. 1992 Academic Article GET IT
Times cited: 9
Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 1992 Academic Article GET IT
Times cited: 78
The activity of cAMP-dependent protein kinase is required at a posttranslational level for induction of voltage-dependent sodium channels by peptide growth factors in PC12 cells. The Journal of cell biology. 1992 Academic Article GET IT
Times cited: 52
Synergistic effects of nerve growth factor and phorbol 12-myristate 13-acetate on rapid motility and process formation in PC12 cells: the role of laminin. Journal of neuroscience research. 1992 Academic Article GET IT
Times cited: 12
A transformed human epithelial cell line that retains tight junctions post crisis. In vitro cellular & developmental biology : journal of the Tissue Culture Association. 1992 Academic Article GET IT
Times cited: 88
Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells. The Journal of biological chemistry. 1991 Academic Article GET IT
Times cited: 132
Nerve growth factor-induced neuronal differentiation after dominant repression of both type I and type II cAMP-dependent protein kinase activities. The Journal of biological chemistry. 1991 Academic Article GET IT
Times cited: 90
Increase in beta-1,4-galactosyltransferase activity during PC12 cell differentiation induced by forskolin and 2-chloroadenosine. Journal of neurochemistry. 1991 Academic Article GET IT
Times cited: 12
Retinoic acid stimulates the differentiation of PC12 cells that are deficient in cAMP-dependent protein kinase. The Journal of cell biology. 1991 Academic Article GET IT
Times cited: 57
The fibroblast growth factors: an emerging family of neural growth factors. Current topics in microbiology and immunology. 1991 Review GET IT
Times cited: 88
Regulation of neural cell survival and differentiation by peptide growth factors. Current opinion in cell biology. 1990 Review GET IT
Times cited: 20
NICER elements: a family of nerve growth factor-inducible cAMP-extinguishable retrovirus-like elements. Proceedings of the National Academy of Sciences of the United States of America. 1990 Academic Article GET IT
Times cited: 14
Nerve growth factor and fibroblast growth factor regulate neurite outgrowth and gene expression in PC12 cells via both protein kinase C- and cAMP-independent mechanisms. The Journal of cell biology. 1990 Academic Article GET IT
Times cited: 97
Role of the cAMP-dependent protein kinase and protein kinase C in regulating the morphological differentiation of PC12 cells. Journal of neuroscience research. 1990 Academic Article GET IT
Times cited: 32
Differential effects of amiodarone and desethylamiodarone on calcium antagonist receptors. Journal of cardiovascular pharmacology. 1990 Academic Article GET IT
Times cited: 14
Nerve growth factor-induced down-regulation of calmodulin-dependent protein kinase III in PC12 cells involves cyclic AMP-dependent protein kinase. Journal of neurochemistry. 1990 Academic Article GET IT
Times cited: 26
Calcium-antagonist receptors in cardiomyopathy. The New England journal of medicine. 1989 Letter GET IT
Alterations in calcium antagonist receptors and sodium-calcium exchange in cardiomyopathic hamster tissues. Circulation research. 1989 Academic Article GET IT
Times cited: 62
Acidic fibroblast growth factor enhances peripheral nerve regeneration in vivo. Plastic and reconstructive surgery. 1989 Academic Article GET IT
Times cited: 138
Bone remodeling signaled by a dihydropyridine- and phenylalkylamine-sensitive calcium channel. Proceedings of the National Academy of Sciences of the United States of America. 1989 Academic Article GET IT
Times cited: 100
Calcium-antagonist receptors in the atrial tissue of patients with hypertrophic cardiomyopathy. The New England journal of medicine. 1989 Academic Article GET IT
Times cited: 90
Heparin potentiates the action of acidic fibroblast growth factor by prolonging its biological half-life. Journal of cellular physiology. 1989 Academic Article GET IT
Times cited: 142
Nerve growth factor regulates gene expression by several distinct mechanisms. Molecular and cellular biology. 1989 Academic Article GET IT
Times cited: 63
Acidic fibroblast growth factor stimulates adrenal chromaffin cells to proliferate and to extend neurites, but is not a long-term survival factor. Neuron. 1988 Academic Article GET IT
Times cited: 98
Induction of process outgrowth in vertebrate and invertebrate cell lines by a 2-pyridinyl thiosemicarbazone. Differentiation; research in biological diversity. 1988 Academic Article GET IT
Times cited: 1
Omega-conotoxin GVIA binding to a high-affinity receptor in brain: characterization, calcium sensitivity, and solubilization. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1988 Academic Article GET IT
Times cited: 129
Phenylalkylamine-sensitive calcium channels in osteoblast-like osteosarcoma cells. Characterization by ligand binding and single channel recordings. The Journal of biological chemistry. 1988 Academic Article GET IT
Times cited: 43
PC12 cells grown on cellulosic filters differentiate in response to NGF and exhibit a polarity not seen when they are grown on solid substrata. In vitro cellular & developmental biology : journal of the Tissue Culture Association. 1988 Academic Article GET IT
Times cited: 8
Sulfated glycosaminoglycans modify growth factor-induced neurite outgrowth in PC12 cells. Journal of cellular physiology. 1988 Academic Article GET IT
Times cited: 68
Acidic fibroblast growth factor enhances regeneration of processes by postnatal mammalian retinal ganglion cells in culture. Proceedings of the National Academy of Sciences of the United States of America. 1988 Academic Article GET IT
Times cited: 149
Calcium antagonist receptors. Clinical and physiological relevance. Annals of the New York Academy of Sciences. 1988 Review GET IT
Times cited: 27
Aminoglycoside effects on voltage-sensitive calcium channels and neurotoxicity. The New England journal of medicine. 1987 Letter GET IT
Times cited: 24
Physiological and pharmacological correlates of calcium antagonist receptors. Journal of cardiovascular pharmacology. 1987 Academic Article GET IT
Times cited: 5
Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA. Proceedings of the National Academy of Sciences of the United States of America. 1986 Academic Article GET IT
Times cited: 275
Neurite outgrowth induced by an endothelial cell mitogen isolated from retina. The Journal of cell biology. 1986 Academic Article GET IT
Times cited: 79
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proceedings of the National Academy of Sciences of the United States of America. 1986 Academic Article GET IT
Times cited: 1057
Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases. The Journal of cell biology. 1986 Academic Article GET IT
Times cited: 113
Calcium antagonist receptors in cardiomyopathic hamster: selective increases in heart, muscle, brain. Science (New York, N.Y.). 1986 Academic Article GET IT
Times cited: 112
NIF (neurite-inducing factor): a novel peptide inducing neurite formation in PC12 cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1986 Academic Article GET IT
Times cited: 14
Structure of catecholamine secretory vesicles from PC12 cells. Journal of neurochemistry. 1985 Academic Article GET IT
Times cited: 33
Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists. Molecular and cellular biology. 1985 Academic Article GET IT
Times cited: 77
Nerve growth factor affects cyclic AMP metabolism, but not by directly stimulating adenylate cyclase activity. Journal of neurochemistry. 1985 Academic Article GET IT
Times cited: 27
Genetic evidence that chloroadenosine increases the specific activity of choline acetyltransferase in PC12 cells via modulation of an adenosine-dependent adenylate cyclase. Neuroscience. 1984 Academic Article GET IT
Times cited: 4
Adenosine inhibits cell division and promotes neurite extension in PC12 cells. Journal of cellular physiology. 1984 Academic Article GET IT
Times cited: 41
Adenosine-dependent activation of tyrosine hydroxylase is defective in adenosine kinase-deficient PC12 cells. Proceedings of the National Academy of Sciences of the United States of America. 1984 Academic Article GET IT
Times cited: 9
Properties of individual nerve terminal proteins identified by two-dimensional gel electrophoresis. Brain research. 1980 Academic Article GET IT
Times cited: 3
Topological organization of proteins in an intracellular secretory organelle: the synaptic vesicle. Proceedings of the National Academy of Sciences of the United States of America. 1979 Academic Article GET IT
Times cited: 35
Nerve terminal proteins of the rabbit visual relay nuclei identified by axonal transport and two-dimensional gel electrophoresis. Brain research. 1979 Academic Article GET IT
Times cited: 19
Maturation of the head of bacteriophage T4: 9-aminoacridine blocks a late step in DNA packaging. Virology. 1979 Academic Article GET IT
Times cited: 5
Biochemistry of neurotransmitter release. Annual review of neuroscience. 1979 Review GET IT
Times cited: 176
Chemical and physical characterization of cholinergic synaptic vesicles. Biochemistry. 1978 Academic Article GET IT
Times cited: 107
Purification of synaptic vesicles from elasmobranch electric organ and the use of biophysical criteria to demonstrate purity. Biochemistry. 1978 Academic Article GET IT
Times cited: 89
Studies on the maturation of the head of bacteriophage T4. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 1976 Academic Article GET IT
Times cited: 4

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Background

education and training

Ph.D., Princeton University 1975
B.S., Loras College 1970

Contact

full name

John A. Wagner

primary email

jawagne@med.cornell.edu

VIVO Weill Cornell Medical College

John A. Wagner Professor of Neuroscience

Publications

selected publications

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email