Malek, Joel A

Publications

Sort by

Co-Author Network

selected publications

Identifying novel interactions of the colon-cancer related APC protein with Wnt-pathway nuclear transcription factors. Cancer cell international. 2022 Academic Article GET IT
Times cited: 111
DNA methylation predicts the outcome of COVID-19 patients with acute respiratory distress syndrome. Journal of translational medicine. 2022 Academic Article GET IT
Application of human RNase P normalization for the realistic estimation of SARS-CoV-2 viral load in wastewater: A perspective from Qatar wastewater surveillance. Environmental technology & innovation. 2022 Academic Article GET IT
Times cited: 83
Discovery of new therapeutic targets in ovarian cancer through identifying significantly non-mutated genes. Journal of translational medicine. 2022 Academic Article GET IT
Times cited: 1
Novel protein contact points among TP53 and minichromosome maintenance complex proteins 2, 3, and 5. Cancer medicine. 2022 Academic Article GET IT
Times cited: 2
The QChip1 knowledgebase and microarray for precision medicine in Qatar. NPJ genomic medicine. 2022 Academic Article GET IT
Times cited: 2
Introduction and expansion of the SARS-CoV-2 B.1.1.7 variant and reinfections in Qatar: A nationally representative cohort study. PLoS medicine. 2021 Academic Article GET IT
Times cited: 22
Scaling-up a fragment-based protein-protein interaction method using a human reference interaction set. Proteins. 2021 Academic Article GET IT
Times cited: 2
One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar. Frontiers in cellular and infection microbiology. 2021 Academic Article GET IT
Times cited: 17
Pfizer-BioNTech mRNA BNT162b2 Covid-19 vaccine protection against variants of concern after one versus two doses. Journal of travel medicine. 2021 Academic Article GET IT
Times cited: 40
Assessment of the Risk of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reinfection in an Intense Reexposure Setting. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 Academic Article GET IT
Times cited: 83
mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar. Nature medicine. 2021 Academic Article GET IT
Times cited: 206
Minor Intron Splicing from Basic Science to Disease. International journal of molecular sciences. 2021 Review GET IT
Times cited: 9
SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy. EClinicalMedicine. 2021 Academic Article GET IT
Times cited: 11
Evidence of Recombination Suppression Blocks on the Y Chromosome of Date Palm (Phoenix dactylifera). Frontiers in plant science. 2021 Academic Article GET IT
Times cited: 469
Deep sequencing of DNA from urine of kidney allograft recipients to estimate donor/recipient-specific DNA fractions. PloS one. 2021 Academic Article GET IT
Regulation of Circular RNA CircNFATC3 in Cancer Cells Alters Proliferation, Migration, and Oxidative Phosphorylation. Frontiers in cell and developmental biology. 2021 Academic Article GET IT
Times cited: 4845
COVID-19 (SARS-CoV-2) outbreak monitoring using wastewater-based epidemiology in Qatar. The Science of the total environment. 2021 Academic Article GET IT
Times cited: 71
Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months. 2020 GET IT
Times cited: 13
Identification of genetic variants controlling RNA editing and their effect on RNA structure stabilization. European journal of human genetics : EJHG. 2020 Academic Article GET IT
Times cited: 4
Long non-coding RNA expression in non-obese women with polycystic ovary syndrome and weight-matched controls. Reproductive biomedicine online. 2020 Academic Article GET IT
Times cited: 3
Genome Diversity and the Origin of the Arabian Horse. Scientific reports. 2020 Academic Article GET IT
Times cited: 34
Deletion of beta-fructofuranosidase (invertase) genes is associated with sucrose content in Date Palm fruit. Plant direct. 2020 Academic Article GET IT
Times cited: 58
Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits. Nature communications. 2020 Academic Article GET IT
Times cited: 34
Point of Care Exome Sequencing Reveals Allelic and Phenotypic Heterogeneity Underlying Mendelian disease in Qatar. Human molecular genetics. 2019 Academic Article GET IT
Times cited: 4
Alterations in long noncoding RNAs in women with and without polycystic ovarian syndrome. Clinical endocrinology. 2019 Academic Article GET IT
Times cited: 14
Identification of human genetic variants controlling circular RNA expression. RNA (New York, N.Y.). 2019 Academic Article GET IT
Times cited: 18
Cell Type-Specific TGF-β Mediated EMT in 3D and 2D Models and Its Reversal by TGF-β Receptor Kinase Inhibitor in Ovarian Cancer Cell Lines. International journal of molecular sciences. 2019 Academic Article GET IT
Times cited: 16
Novel subpopulations in date palm (Phoenix dactylifera) identified by population-wide organellar genome sequencing. BMC genomics. 2019 Academic Article GET IT
Times cited: 13
Silencing of ANKRD12 circRNA induces molecular and functional changes associated with invasive phenotypes. BMC cancer. 2019 Academic Article GET IT
Times cited: 29
High-resolution protein-protein interaction mapping using all-versus-all sequencing (AVA-Seq). The Journal of biological chemistry. 2019 Academic Article GET IT
Times cited: 4
Genotyping-by-sequencing identifies date palm clone preference in agronomics of the State of Qatar. PloS one. 2018 Academic Article GET IT
Times cited: 4
Author Correction: Genus-wide sequencing support a two-locus model for sex-determination in Phoenix. Nature communications. 2018 Academic Article GET IT
Times cited: 2
Genus-wide sequencing supports a two-locus model for sex-determination in Phoenix. Nature communications. 2018 Academic Article GET IT
Times cited: 62
Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population. PloS one. 2018 Academic Article GET IT
Times cited: 4
Point-of-care whole-exome sequencing of idiopathic male infertility. Genetics in medicine : official journal of the American College of Medical Genetics. 2018 Academic Article GET IT
Times cited: 41
A comprehensive metabolomic data set of date palm fruit. Data in brief. 2018 Academic Article GET IT
Times cited: 11
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation. Human molecular genetics. 2018 Academic Article GET IT
Times cited: 22
Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population. Nature communications. 2018 Academic Article GET IT
Times cited: 41
Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome. Nature communications. 2017 Academic Article GET IT
Times cited: 9
Connecting genetic risk to disease end points through the human blood plasma proteome. Nature communications. 2017 Academic Article GET IT
Times cited: 279
Mutation in noncoding RNA RNU12 causes early onset cerebellar ataxia. Annals of neurology. 2017 Academic Article GET IT
Times cited: 54
Correction: Type 2 Diabetes Risk Allele Loci in the Qatari Population. PloS one. 2016 Article GET IT
Times cited: 20
Type 2 Diabetes Risk Allele Loci in the Qatari Population. PloS one. 2016 Academic Article GET IT
Times cited: 20
The Qatar genome: a population-specific tool for precision medicine in the Middle East. Human genome variation. 2016 Academic Article GET IT
Times cited: 74
Altered expression pattern of circular RNAs in primary and metastatic sites of epithelial ovarian carcinoma. Oncotarget. 2016 Academic Article GET IT
Times cited: 129
Correction: Preferential Allele Expression Analysis Identifies Shared Germline and Somatic Driver Genes in Advanced Ovarian Cancer. PLoS genetics. 2016 Article GET IT
Times cited: 10
Preferential Allele Expression Analysis Identifies Shared Germline and Somatic Driver Genes in Advanced Ovarian Cancer. PLoS genetics. 2016 Academic Article GET IT
Times cited: 10
Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations. Genome research. 2016 Academic Article GET IT
Times cited: 62
Metabolomics of dates (Phoenix dactylifera) reveals a highly dynamic ripening process accounting for major variation in fruit composition. BMC plant biology. 2015 Academic Article GET IT
Times cited: 34
Whole genome re-sequencing of date palms yields insights into diversification of a fruit tree crop. Nature communications. 2015 Academic Article GET IT
Times cited: 107
Copy number variations in the genome of the Qatari population. BMC genomics. 2015 Academic Article GET IT
Times cited: 8
A Genome-Wide Survey of Date Palm Cultivars Supports Two Major Subpopulations in Phoenix dactylifera. G3 (Bethesda, Md.). 2015 Academic Article GET IT
Times cited: 39
K-core decomposition of a protein domain co-occurrence network reveals lower cancer mutation rates for interior cores. Journal of clinical bioinformatics. 2015 Academic Article GET IT
Times cited: 1
Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food intake. Journal of translational medicine. 2014 Academic Article GET IT
Times cited: 23
Where cancer genomics should go next: a clinician's perspective. Human molecular genetics. 2014 Review GET IT
Times cited: 14
A first genetic map of date palm (Phoenix dactylifera) reveals long-range genome structure conservation in the palms. BMC genomics. 2014 Academic Article GET IT
Times cited: 66
Whole genome sequencing identifies a novel occludin mutation in microcephaly with band-like calcification and polymicrogyria that extends the phenotypic spectrum. American journal of medical genetics. Part A. 2014 Letter GET IT
Times cited: 12
Mesenchymal cell interaction with ovarian cancer cells induces a background dependent pro-metastatic transcriptomic profile. Journal of translational medicine. 2014 Academic Article GET IT
Times cited: 25
Longitudinal study of recurrent metastatic melanoma cell lines underscores the individuality of cancer biology. The Journal of investigative dermatology. 2013 Academic Article GET IT
Times cited: 2
Exome sequencing identifies potential risk variants for Mendelian disorders at high prevalence in Qatar. Human mutation. 2013 Academic Article GET IT
Times cited: 41
Prevalence of the apolipoprotein E Arg145Cys dyslipidemia at-risk polymorphism in African-derived populations. The American journal of cardiology. 2013 Academic Article GET IT
Times cited: 12
TNRC9 downregulates BRCA1 expression and promotes breast cancer aggressiveness. Cancer research. 2013 Academic Article GET IT
Times cited: 34
Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population. PloS one. 2012 Academic Article GET IT
Times cited: 16
High-prevalence and broad spectrum of Cell Adhesion and Extracellular Matrix gene pathway mutations in epithelial ovarian cancer. Journal of clinical bioinformatics. 2012 Academic Article GET IT
Times cited: 2716
Gene expression analysis of matched ovarian primary tumors and peritoneal metastasis. Journal of translational medicine. 2012 Academic Article GET IT
Times cited: 20
Comprehensive characterization of mesenchymal stem cells from human placenta and fetal membrane and their response to osteoactivin stimulation. Stem cells international. 2012 Academic Article GET IT
Times cited: 59
Mesenchymal cell interaction with ovarian cancer cells triggers pro-metastatic properties. PloS one. 2012 Academic Article GET IT
Times cited: 41
DNA-based assays to distinguish date palm (Arecaceae) gender. American journal of botany. 2011 Academic Article GET IT
Times cited: 30
Copy number variation analysis of matched ovarian primary tumors and peritoneal metastasis. PloS one. 2011 Academic Article GET IT
Times cited: 41
De novo genome sequencing and comparative genomics of date palm (Phoenix dactylifera). Nature biotechnology. 2011 Academic Article GET IT
Times cited: 293
New microsatellite markers for assessment of genetic diversity in date palm (Phoenix dactylifera L.). 3 Biotech. 2011 Academic Article GET IT
Times cited: 65
Tumor associated mesenchymal stem cells protects ovarian cancer cells from hyperthermia through CXCL12. International journal of cancer. 2011 Academic Article GET IT
Times cited: 92
ALLPATHS 2: small genomes assembled accurately and with high continuity from short paired reads. Genome biology. 2009 Academic Article GET IT
Times cited: 136
Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding. Genome research. 2009 Academic Article GET IT
Times cited: 399
Rapid whole-genome mutational profiling using next-generation sequencing technologies. Genome research. 2008 Academic Article GET IT
Times cited: 215
A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning. Genome research. 2008 Academic Article GET IT
Times cited: 462
The complete genome sequence and analysis of the epsilonproteobacterium Arcobacter butzleri. PloS one. 2007 Academic Article GET IT
Times cited: 175
Sequencing genomes from single cells by polymerase cloning. Nature biotechnology. 2006 Academic Article GET IT
Times cited: 315
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome research. 2004 Academic Article GET IT
Times cited: 427
Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes. Proceedings of the National Academy of Sciences of the United States of America. 2004 Academic Article GET IT
Times cited: 213
Protein interaction mapping on a functional shotgun sequence of Rickettsia sibirica. Nucleic acids research. 2004 Academic Article GET IT
Times cited: 35
Radiation hybrid map, physical map, and low-pass genomic sequence of the canine prcd region on CFA9 and comparative mapping with the syntenic region on human chromosome 17. Genomics. 2003 Academic Article GET IT
Times cited: 15
Annotation of novel proteins utilizing a functional genome shotgun coupled with high-throughput protein interaction mapping. Cold Spring Harbor symposia on quantitative biology. 2003 Academic Article GET IT
Times cited: 1
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 2002 Academic Article GET IT
Times cited: 1568
The genome sequence of the malaria mosquito Anopheles gambiae. Science (New York, N.Y.). 2002 Academic Article GET IT
Times cited: 1629
The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts. Proceedings of the National Academy of Sciences of the United States of America. 2002 Academic Article GET IT
Times cited: 392
A physical map of the mouse genome. Nature. 2002 Academic Article GET IT
Times cited: 266
Mouse BAC ends quality assessment and sequence analyses. Genome research. 2001 Academic Article GET IT
Times cited: 47
Abundant protein domains occur in proportion to proteome size. Genome biology. 2001 Academic Article GET IT
Times cited: 3
Optimized growth conditions for direct amplification of cDNA clone inserts from culture. BioTechniques. 2001 Academic Article GET IT
Times cited: 4
Degradation of persistent RNA in RNase-containing, high-throughput alkaline lysis DNA preparations. BioTechniques. 2000 Academic Article GET IT
Times cited: 1
Human BAC ends quality assessment and sequence analyses. Genomics. 2000 Academic Article GET IT
Times cited: 33
Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 Academic Article GET IT
Times cited: 1215
Transcriptional regulation of the proton-translocating ATPase (atpIBEFHAGDC) operon of Escherichia coli: control by cell growth rate. Journal of bacteriology. 1996 Academic Article GET IT
Times cited: 64

more ...

less ...

Background

education and training

Ph.D., University of Paris XI, Kremelin Bicetre (France) 2011
M.Sc., The Johns Hopkins University 2003
B.Sc., University of California, Los Angeles 1996

Contact

full name

Joel A Malek

primary email

jom2042@qatar-med.cornell.edu

VIVO Weill Cornell Medical College

Joel A Malek Associate Professor of Genetic Medicine

Publications

selected publications

Background

education and training

Contact

full name

primary email