Osborne, Joseph R.

Publications

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Co-Author Network

selected publications

Prognostic value of neutrophil-to-lymphocyte ratio in patients with metastatic castration-resistant prostate cancer receiving prostate-specific membrane antigen targeted radionuclide therapy. The Prostate. 2023 Academic Article GET IT
Cost-Effectiveness Analysis of ⁶⁸Ga-DOTATATE PET/MRI in Radiotherapy Planning in Patients with Intermediate-Risk Meningioma. AJNR. American journal of neuroradiology. 2023 Academic Article GET IT
SNMMI Consensus Statement on Patient Selection and Appropriate Use of ¹⁷⁷Lu-PSMA-617 Radionuclide Therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2023 Academic Article GET IT
[68 Ga]-DOTATATE PET/MR-based evaluation of physiologic somatostatin receptor 2 expression in the adult pituitary gland as a function of age and sex in a prospective cohort. Pituitary. 2023 Academic Article GET IT
Joint EANM/SNMMI procedure guideline for the use of ¹⁷⁷Lu-labeled PSMA-targeted radioligand-therapy (¹⁷⁷Lu-PSMA-RLT). European journal of nuclear medicine and molecular imaging. 2023 Academic Article GET IT
Times cited: 5
Complex implementation factors demonstrated when evaluating cost-effectiveness and monitoring racial disparities associated with [¹⁸F]DCFPyL PET/CT in prostate cancer men. Scientific reports. 2023 Academic Article GET IT
The use of single-timepoint images to link administered radioiodine activity (MBq) to a prescribed lesion radiation-absorbed dose (cGy): a regression-based prediction interval tool for the management of well-differentiated thyroid cancer patients. European journal of nuclear medicine and molecular imaging. 2023 Academic Article GET IT
α-Labeling of J591, an Antibody Targeting Prostate-Specific Membrane Antigen: The Technique and Considerations from the First Dedicated Production Lab at an Academic Institution in the United States. Journal of nuclear medicine technology. 2023 Academic Article GET IT
Response to RL-225Ac in prostate cancer: Effect of prior treatment with RL-177Lu: A systematic review of the literature. The Prostate. 2023 Review GET IT
Times cited: 1
In vivo Brain Estrogen Receptor Expression By Neuroendocrine Aging And Relationships With Gray Matter Volume, Bio-Energetics, and Clinical Symptomatology. Research square. 2023 Article GET IT
Times cited: 25
PSMA PET/CT: joint EANM procedure guideline/SNMMI procedure standard for prostate cancer imaging 2.0. European journal of nuclear medicine and molecular imaging. 2023 Academic Article GET IT
Times cited: 4
Cyclotron vs generator-produced 68Ga PSMA: a single-institution, prospective clinical trial. Translational oncology. 2022 Academic Article GET IT
Times cited: 10
Access to cardiac PET/CT by sarcoidosis patients and cost-effectiveness analysis of cardiac PET/MR compared to the standard of care. Clinical imaging. 2022 Academic Article GET IT
Evaluating diagnostic accuracy and determining optimal diagnostic thresholds of different approaches to [⁶⁸Ga]-DOTATATE PET/MRI analysis in patients with meningioma. Scientific reports. 2022 Academic Article GET IT
Times cited: 2
Correction to: [⁸⁹Zr]Zr‑huJ591 immuno‑PET targeting PSMA in IDH mutant anaplastic oligodendroglioma. European journal of nuclear medicine and molecular imaging. 2022 Article GET IT
Dynamic ⁶⁸Ga-DOTATATE PET/MRI in the Diagnosis and Management of Intracranial Meningiomas. Radiology. Imaging cancer. 2022 Academic Article GET IT
Times cited: 3
PET/MR Imaging of Somatostatin Receptor Expression and Tumor Vascularity in Meningioma: Implications for Pathophysiology and Tumor Outcomes. Frontiers in oncology. 2022 Academic Article GET IT
Times cited: 6
Pilot study of the diagnostic utility of ⁸⁹ Zr-df-IAB2M and ⁶⁸ Ga-PSMA-11 PET imaging and multiparametric MRI in localized prostate cancer. The Prostate. 2022 Academic Article GET IT
Times cited: 6
Utility of [18F]-fluoroestradiol (FES) PET/CT with dedicated brain acquisition in differentiating brain metastases from posttreatment change in estrogen receptor-positive breast cancer. Neuro-oncology advances. 2021 Academic Article GET IT
Prostate-Specific Membrane Antigen Positron Emission Tomography and the New Algorithm for Patients With Prostate Cancer Prior to Prostatectomy. JAMA oncology. 2021 Comment GET IT
Times cited: 2
68Ga-PSMA-HBED-CC PET/MRI is superior to multiparametric magnetic resonance imaging in men with biochemical recurrent prostate cancer: A prospective single-institutional study. Translational oncology. 2021 Academic Article GET IT
Times cited: 18
[⁸⁹Zr]Zr-huJ591 immuno-PET targeting PSMA in IDH mutant anaplastic oligodendroglioma. European journal of nuclear medicine and molecular imaging. 2021 Academic Article GET IT
Times cited: 4
Heuristic scoring method utilizing FDG-PET statistical parametric mapping in the evaluation of suspected Alzheimer disease and frontotemporal lobar degeneration. American journal of nuclear medicine and molecular imaging. 2021 Academic Article GET IT
Review of commonly used prostate specific PET tracers used in prostate cancer imaging in current clinical practice. Clinical imaging. 2021 Review GET IT
Times cited: 4
A Phase II, Nonrandomized Open Trial Assessing Pain Efficacy with Radium-223 in Symptomatic Metastatic Castration-resistant Prostate Cancer. Clinical genitourinary cancer. 2021 Academic Article GET IT
Times cited: 2
Prostate-Specific Membrane Antigen Uptake and Survival in Metastatic Castration-Resistant Prostate Cancer. Frontiers in oncology. 2021 Academic Article GET IT
Times cited: 198
A simple strategy to reduce the salivary gland and kidney uptake of PSMA-targeting small molecule radiopharmaceuticals. European journal of nuclear medicine and molecular imaging. 2021 Academic Article GET IT
Times cited: 22
[⁶⁸Ga]-DOTATATE PET/MRI as an adjunct imaging modality for radiation treatment planning of meningiomas. Neuro-oncology advances. 2021 Academic Article GET IT
Times cited: 19
Imaging expression of prostate-specific membrane antigen and response to PSMA-targeted β-emitting radionuclide therapies in metastatic castration-resistant prostate cancer. The Prostate. 2021 Academic Article GET IT
Times cited: 7
[68Ga]-DOTATATE PET/CT and PET/MRI in the diagnosis and management of esthesioneuroblastoma: illustrative cases. 2021 GET IT
Molecular Imaging of Striatal Dopaminergic Neuronal Loss and the Neurovascular Unit in Parkinson Disease. Frontiers in neuroscience. 2020 Academic Article GET IT
Times cited: 951
A Conversation Between Joseph Osborne and Thomas Hope. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Article GET IT
Phase I trial of docetaxel plus lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 (¹⁷⁷Lu-J591) for metastatic castration-resistant prostate cancer. Urologic oncology. 2020 Academic Article GET IT
Times cited: 20
Somatostatin receptor-2 negative meningioma: pathologic correlation and imaging implications. 2020 GET IT
Times cited: 6
Pilot Study of Hyperfractionated Dosing of Lutetium-177-Labeled Antiprostate-Specific Membrane Antigen Monoclonal Antibody J591 (¹⁷⁷ Lu-J591) for Metastatic Castration-Resistant Prostate Cancer. The oncologist. 2020 Academic Article GET IT
Times cited: 24
Thyroid Cancer Bone Metastasis: Survival and Genomic Characteristics of a Large Tertiary Care Cohort. Clinical nuclear medicine. 2019 Academic Article GET IT
Times cited: 11
George de Hevesy in America. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Letter GET IT
Carotid Plaque Positron Emission Tomography Imaging and Cerebral Ischemic Disease. Stroke. 2019 Review GET IT
Times cited: 21
Association of Black Race With Prostate Cancer-Specific and Other-Cause Mortality. JAMA oncology. 2019 Academic Article GET IT
Times cited: 227
Presynaptic dopamine deficit in minimally conscious state patients following traumatic brain injury. Brain : a journal of neurology. 2019 Academic Article GET IT
Times cited: 22
Thyroid Cancer Brain Metastasis: Survival and Genomic Characteristics of a Large Tertiary Care Cohort. Clinical nuclear medicine. 2019 Academic Article GET IT
Times cited: 11
Gallium-68 DOTATATE PET in the Evaluation of Intracranial Meningiomas. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2019 Academic Article GET IT
Times cited: 42
Phase 1/2 study of fractionated dose lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 (¹⁷⁷ Lu-J591) for metastatic castration-resistant prostate cancer. Cancer. 2019 Academic Article GET IT
Times cited: 73
Molecular imaging and therapy of somatostatin receptor positive tumors. Clinical imaging. 2019 Review GET IT
Times cited: 22
Cancer Health Impact Program (CHIP): Identifying Social and Demographic Associations of mHealth Access and Cancer Screening Behaviors Among Brooklyn, New York, Residents. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2019 Academic Article GET IT
Times cited: 2
Theragnostic Target, Prostate-Specific Membrane Antigen-Also Specific for Nonprostatic Malignancies. International journal of radiation oncology, biology, physics. 2018 Academic Article GET IT
Times cited: 5
Immediate Postablation ¹⁸F-FDG Injection and Corresponding SUV Are Surrogate Biomarkers of Local Tumor Progression After Thermal Ablation of Colorectal Carcinoma Liver Metastases. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 26
Positron Emission Tomography/Computed Tomography-Based Assessments of Androgen Receptor Expression and Glycolytic Activity as a Prognostic Biomarker for Metastatic Castration-Resistant Prostate Cancer. JAMA oncology. 2018 Academic Article GET IT
Times cited: 71
Erratum to: Repeatability of [⁶⁸Ga]DKFZ11-PSMA PET Scans for Detecting Prostate-specific Membrane Antigen-positive Prostate Cancer. Molecular imaging and biology. 2017 Academic Article GET IT
Repeatability of [⁶⁸Ga]DKFZ11-PSMA PET Scans for Detecting Prostate-specific Membrane Antigen-positive Prostate Cancer. Molecular imaging and biology. 2017 Academic Article GET IT
Times cited: 6
A pilot study of neuropsychological functions, APOE and amyloid imaging in patients with gliomas. Journal of neuro-oncology. 2017 Academic Article GET IT
Times cited: 11
Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer discovery. 2017 Academic Article GET IT
Times cited: 77
Interventional Cultural and Language Assistance Program: Associations between Cultural and Linguistic Factors and Satisfaction with Cancer Care. Journal of community medicine & health education. 2017 Academic Article GET IT
Redifferentiating Thyroid Cancer: Selumetinib-enhanced Radioiodine Uptake in Thyroid Cancer. Molecular imaging and radionuclide therapy. 2017 Academic Article GET IT
Times cited: 7
Pan-Cancer Analysis of Genomic Sequencing Among the Elderly. International journal of radiation oncology, biology, physics. 2017 Academic Article GET IT
Times cited: 8
Anatomic and functional imaging in the diagnosis of spine metastases and response assessment after spine radiosurgery. Neurosurgical focus. 2017 Review GET IT
Times cited: 17
FDG-Avid Intrathecal Inflammation Following Administration of Intrathecal Methotrexate. 2016 GET IT
Times cited: 1
miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin. Experimental cell research. 2016 Academic Article GET IT
Times cited: 39
Patterns of Lymph Node Failure after Dose-escalated Radiotherapy: Implications for Extended Pelvic Lymph Node Coverage. European urology. 2016 Academic Article GET IT
Times cited: 55
Racial/Ethnic Disparities in Genomic Sequencing. JAMA oncology. 2016 Academic Article GET IT
Times cited: 190
miR-1207-3p Is a Novel Prognostic Biomarker of Prostate Cancer. Translational oncology. 2016 Academic Article GET IT
Times cited: 15
Radium-223 outcomes after multiple lines of metastatic castration-resistant prostate cancer therapy in clinical practice: implication of pre-treatment spinal epidural disease. Prostate cancer and prostatic diseases. 2016 Academic Article GET IT
Times cited: 4
Individual Patient Data Analysis of Randomized Clinical Trials: Impact of Black Race on Castration-resistant Prostate Cancer Outcomes. European urology focus. 2016 Academic Article GET IT
Times cited: 18
Metabolic tumor volume and total lesion glycolysis on FDG-PET/CT can predict overall survival after (90)Y radioembolization of colorectal liver metastases: A comparison with SUVmax, SUVpeak, and RECIST 1.0. European journal of radiology. 2016 Academic Article GET IT
Times cited: 44
Stereotactic body radiotherapy for metastatic spinal sarcoma: a detailed patterns-of-failure study. Journal of neurosurgery. Spine. 2016 Academic Article GET IT
Times cited: 24
Early magnetic resonance imaging biomarkers to predict local control after high dose stereotactic body radiotherapy for patients with sarcoma spine metastases. The spine journal : official journal of the North American Spine Society. 2016 Academic Article GET IT
Times cited: 24
ACR Practice Parameter for the Performance of Therapy With Unsealed Radiopharmaceutical Sources. 2016 GET IT
Times cited: 2
Targeting of radiolabeled J591 antibody to PSMA-expressing tumors: optimization of imaging and therapy based on non-linear compartmental modeling. EJNMMI research. 2016 Academic Article GET IT
Times cited: 56
A Perspective of the Future of Nuclear Medicine Training and Certification. Seminars in nuclear medicine. 2016 Review GET IT
Times cited: 12
Guest Editorial. Seminars in nuclear medicine. 2016 Editorial Article GET IT
Times cited: 3
PVT1 Exon 9: A Potential Biomarker of Aggressive Prostate Cancer?. International journal of environmental research and public health. 2015 Academic Article GET IT
Times cited: 23
The Influence of Diabetes Mellitus and Metformin on Distant Metastases in Oropharyngeal Cancer: A Multicenter Study. International journal of radiation oncology, biology, physics. 2015 Academic Article GET IT
Times cited: 16
Roundtable on the Future of Nuclear Medicine Training. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2015 Letter GET IT
Times cited: 3
Comparison of 18F-FDG PET/CT for Systemic Staging of Newly Diagnosed Invasive Lobular Carcinoma Versus Invasive Ductal Carcinoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2015 Academic Article GET IT
Times cited: 66
Striatal dopamine type 2 receptor availability in anorexia nervosa. Psychiatry research. 2015 Academic Article GET IT
Times cited: 28
A Phase I/II Study for Analytic Validation of 89Zr-J591 ImmunoPET as a Molecular Imaging Agent for Metastatic Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Academic Article GET IT
Times cited: 148
Radioembolization as a Salvage Therapy for Heavily Pretreated Patients With Colorectal Cancer Liver Metastases: Factors That Affect Outcomes. Clinical colorectal cancer. 2015 Academic Article GET IT
Times cited: 39
Disparities in castration-resistant prostate cancer trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2015 Academic Article GET IT
Times cited: 38
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen: pharmacokinetics and biodistribution studies in healthy subjects and patients with metastatic prostate cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2014 Academic Article GET IT
Times cited: 109
⁸⁹Zr-huJ591 immuno-PET imaging in patients with advanced metastatic prostate cancer. European journal of nuclear medicine and molecular imaging. 2014 Academic Article GET IT
Times cited: 112
Phase 1 study of radiosensitization using bortezomib in patients with relapsed non-Hodgkin lymphoma receiving radioimmunotherapy with 131I-tositumomab. Leukemia & lymphoma. 2014 Academic Article GET IT
Times cited: 9
Utility of FDG-PET in clinical neuroendocrine prostate cancer. The Prostate. 2014 Academic Article GET IT
Times cited: 46
Pairwise comparison of 89Zr- and 124I-labeled cG250 based on positron emission tomography imaging and nonlinear immunokinetic modeling: in vivo carbonic anhydrase IX receptor binding and internalization in mouse xenografts of clear-cell renal cell carcinoma. European journal of nuclear medicine and molecular imaging. 2014 Academic Article GET IT
Times cited: 60
A prospective pilot study of (89)Zr-J591/prostate specific membrane antigen positron emission tomography in men with localized prostate cancer undergoing radical prostatectomy. The Journal of urology. 2013 Academic Article GET IT
Times cited: 64
Cholecystokinin-assisted hydrodissection of the gallbladder fossa during FDG PET/CT-guided liver ablation. 2013 GET IT
Times cited: 6
Phase II study of Lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for metastatic castration-resistant prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Academic Article GET IT
Times cited: 321
PSMA-targeted dendrimers: a patent evaluation (WO2012078534). Expert opinion on therapeutic patents. 2013 Academic Article GET IT
Times cited: 1
Early assessment of radiation response using a novel functional imaging modality -- [18F]fluorocholine PET (FCH-PET): a pilot study. Discovery medicine. 2012 Academic Article GET IT
Times cited: 14
Prostate-specific membrane antigen-based imaging. Urologic oncology. 2012 Review GET IT
Times cited: 84
Review of salvage therapy for biochemically recurrent prostate cancer: the role of imaging and rationale for systemic salvage targeted anti-prostate-specific membrane antigen radioimmunotherapy. Advances in urology. 2012 Academic Article GET IT
Times cited: 38
A worrisome interventricular septum: more than meets the eye. 2011 GET IT
Times cited: 1
Automated framework for digital radiation dose index reporting from CT dose reports. AJR. American journal of roentgenology. 2011 Academic Article GET IT
Times cited: 14
18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer research. 2011 Academic Article GET IT
Times cited: 103
Imaging inflammation in a patient with epilepsy due to focal cortical dysplasia. 2011 GET IT
Times cited: 55
Altered biodistribution of radiopharmaceuticals: role of radiochemical/pharmaceutical purity, physiological, and pharmacologic factors. Seminars in nuclear medicine. 2010 Review GET IT
Times cited: 76
18F-FDG PET of locally invasive breast cancer and association of estrogen receptor status with standardized uptake value: microarray and immunohistochemical analysis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010 Academic Article GET IT
Times cited: 88
Anti-prostate-specific membrane antigen-based radioimmunotherapy for prostate cancer. Cancer. 2010 Academic Article GET IT
Times cited: 122
Targeted elimination of prostate cancer by genetically directed human T lymphocytes. Cancer research. 2005 Academic Article GET IT
Times cited: 100
Spontaneous neural activity is required for the establishment and maintenance of the olfactory sensory map. Neuron. 2004 Academic Article GET IT
Times cited: 299
Mice cloned from olfactory sensory neurons. Nature. 2004 Academic Article GET IT
Times cited: 310
Genetic ablation and restoration of the olfactory topographic map. Cell. 2000 Academic Article GET IT
Times cited: 114

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Research

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Co-investigator Network

Funding awarded

Understanding the dynamic interactions between tau pathology and microgliamediated inflammation in Alzheimer''s Disease awarded by National Institute on Aging Co-Investigator 2021 - 2026
Heating cold prostate tumors with PSMA-targeted alpha therapy and pembrolizumab awarded by United States Department of Defense Co-Investigator 2020 - 2024
MRI Detection of CarotId Plaques as a mecHanism for Embolic strokes of undeteRmined source (MRI DECIPHER) awarded by National Heart, Lung, & Blood Institute Co-Investigator 2019 - 2024

New PET/CT System for Human and Non-human Primate Imaging awarded by National Institutes of Health, Office of the Director Key Personnel 2023 - 2024
Major Cyclotron Upgrades and Refurbishment awarded by National Institutes of Health, Office of the Director Key Personnel 2021 - 2023

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Background

education and training

M.D., Ph.D., Columbia University College of Physicians and Surgeons 2001
B.S., Brown University 1992

Contact

full name

Joseph R. Osborne

primary email

jro7001@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Joseph R. Osborne Professor of Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage