Keshari, Kayvan Rahimi

Publications

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selected publications

Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1. Cell metabolism. 2019 Academic Article GET IT
Times cited: 65
Hyperpolarized [6-¹³C,¹⁵N₃]-Arginine as a Probe for in Vivo Arginase Activity. ACS chemical biology. 2019 Academic Article GET IT
Times cited: 11
Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes. Scientific reports. 2018 Academic Article GET IT
Times cited: 12
Metabolic Imaging of the Human Brain with Hyperpolarized ¹³C Pyruvate Demonstrates ¹³C Lactate Production in Brain Tumor Patients. Cancer research. 2018 Academic Article GET IT
Times cited: 146
Targeted AKT Inhibition in Prostate Cancer Cells and Spheroids Reduces Aerobic Glycolysis and Generation of Hyperpolarized [1-¹³C] Lactate. Molecular cancer research : MCR. 2018 Academic Article GET IT
Times cited: 15
In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors. Cell metabolism. 2017 Academic Article GET IT
Times cited: 66
Noninvasive Interrogation of Cancer Metabolism with Hyperpolarized ¹³C MRI. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Review GET IT
Times cited: 17
Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma. Cancer research. 2017 Academic Article GET IT
Times cited: 17
Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models. Cancer research. 2017 Academic Article GET IT
Times cited: 20
Hyperpolarized ¹³C pyruvate mouse brain metabolism with absorptive-mode EPSI at 1T. Journal of magnetic resonance (San Diego, Calif. : 1997). 2016 Academic Article GET IT
Times cited: 8
Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field. Scientific reports. 2016 Academic Article GET IT
Times cited: 13
Separation of extra- and intracellular metabolites using hyperpolarized (13)C diffusion weighted MR. Journal of magnetic resonance (San Diego, Calif. : 1997). 2016 Academic Article GET IT
Times cited: 19
Remodeling the Vascular Microenvironment of Glioblastoma with α-Particles. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 16
Non-invasive PET Imaging of PARP1 Expression in Glioblastoma Models. Molecular imaging and biology. 2016 Academic Article GET IT
Times cited: 58
Hyperpolarization MRI: Preclinical Models and Potential Applications in Neuroradiology. Topics in magnetic resonance imaging : TMRI. 2016 Review GET IT
Times cited: 16
The Potential of Metabolic Imaging. Seminars in nuclear medicine. 2016 Review GET IT
Times cited: 24
Caged [(18)F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography. Bioconjugate chemistry. 2015 Academic Article GET IT
Times cited: 32
Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor. NMR in biomedicine. 2015 Academic Article GET IT
Times cited: 39
Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor. The Prostate. 2015 Academic Article GET IT
Times cited: 27
Novel Approaches to Imaging Tumor Metabolism. Cancer journal (Sudbury, Mass.). 2015 Review GET IT
Times cited: 23
A boronate-caged [¹⁸F]FLT probe for hydrogen peroxide detection using positron emission tomography. Journal of the American Chemical Society. 2014 Academic Article GET IT
Times cited: 105
Rapid in vivo apparent diffusion coefficient mapping of hyperpolarized (13) C metabolites. Magnetic resonance in medicine. 2014 Academic Article GET IT
Times cited: 25
Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance. Diabetes. 2014 Academic Article GET IT
Times cited: 58
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 163
Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization. Chemical Society reviews. 2013 Review GET IT
Times cited: 261
Hyperpolarized [1-13C]dehydroascorbate MR spectroscopy in a murine model of prostate cancer: comparison with 18F-FDG PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 47
Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor. The Prostate. 2013 Academic Article GET IT
Times cited: 82
Diffusion MR of hyperpolarized 13C molecules in solution. The Analyst. 2013 Academic Article GET IT
Times cited: 26
Hyperpolarized 13C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas. Cancer research. 2012 Academic Article GET IT
Times cited: 86
Effect of oxygen concentration on viability and metabolism in a fluidized-bed bioartificial liver using ³¹P and ¹³C NMR spectroscopy. Tissue engineering. Part C, Methods. 2012 Academic Article GET IT
Times cited: 9
Generating contrast in hyperpolarized 13C MRI using ligand-receptor interactions. The Analyst. 2012 Academic Article GET IT
Times cited: 18
Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging. Proceedings of the National Academy of Sciences of the United States of America. 2011 Academic Article GET IT
Times cited: 121
In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-(13)C]alanine. Magnetic resonance imaging. 2011 Academic Article GET IT
Times cited: 31
Correlation of phospholipid metabolites with prostate cancer pathologic grade, proliferative status and surgical stage - impact of tissue environment. NMR in biomedicine. 2011 Academic Article GET IT
Times cited: 45
A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent. Journal of the American Chemical Society. 2011 Academic Article GET IT
Times cited: 87
Imaging of blood flow using hyperpolarized [(13)C]urea in preclinical cancer models. Journal of magnetic resonance imaging : JMRI. 2011 Academic Article GET IT
Times cited: 84
Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo. Journal of magnetic resonance (San Diego, Calif. : 1997). 2010 Academic Article GET IT
Times cited: 142
Metabolic assessment of a novel chronic myelogenous leukemic cell line and an imatinib resistant subline by H NMR spectroscopy. Metabolomics : Official journal of the Metabolomic Society. 2010 Academic Article GET IT
Times cited: 750
Hyperpolarized (13)C spectroscopy and an NMR-compatible bioreactor system for the investigation of real-time cellular metabolism. Magnetic resonance in medicine. 2010 Academic Article GET IT
Times cited: 61
Metabolic, pathologic, and genetic analysis of prostate tissues: quantitative evaluation of histopathologic and mRNA integrity after HR-MAS spectroscopy. NMR in biomedicine. 2009 Academic Article GET IT
Times cited: 30
Hyperpolarized [2-13C]-fructose: a hemiketal DNP substrate for in vivo metabolic imaging. Journal of the American Chemical Society. 2009 Academic Article GET IT
Times cited: 92
Generation of hyperpolarized substrates by secondary labeling with [1,1-13C] acetic anhydride. Proceedings of the National Academy of Sciences of the United States of America. 2009 Academic Article GET IT
Times cited: 43
Evaluation of the ERETIC method as an improved quantitative reference for 1H HR-MAS spectroscopy of prostate tissue. Magnetic resonance in medicine. 2009 Academic Article GET IT
Times cited: 61
(1)H HR-MAS spectroscopy for quantitative measurement of choline concentration in amniotic fluid as a marker of fetal lung maturity: inter- and intraobserver reproducibility study. Journal of magnetic resonance imaging : JMRI. 2008 Academic Article GET IT
Times cited: 19
Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR-MAS spectroscopy of biopsy tissues. Magnetic resonance in medicine. 2008 Academic Article GET IT
Times cited: 164
Quantification of choline- and ethanolamine-containing metabolites in human prostate tissues using 1H HR-MAS total correlation spectroscopy. Magnetic resonance in medicine. 2008 Academic Article GET IT
Times cited: 101
Lactic acid and proteoglycans as metabolic markers for discogenic back pain. Spine. 2008 Academic Article GET IT
Times cited: 53
Quantitative analysis of prostate metabolites using 1H HR-MAS spectroscopy. Magnetic resonance in medicine. 2006 Academic Article GET IT
Times cited: 232
Correlation of HR-MAS spectroscopy derived metabolite concentrations with collagen and proteoglycan levels and Thompson grade in the degenerative disc. Spine. 2005 Academic Article GET IT
Times cited: 34
Fourier Transform Infrared Imaging of focal lesions in human osteoarthritic cartilage. European cells & materials. 2005 Academic Article GET IT
Times cited: 55
Characterization of intervertebral disc degeneration by high-resolution magic angle spinning (HR-MAS) spectroscopy. Magnetic resonance in medicine. 2005 Academic Article GET IT
Times cited: 43

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Background

education and training

Ph.D., University of North Carolina 2009
B.A., University of California, Berkeley 2003

Contact

full name

Kayvan Rahimi Keshari

VIVO Weill Cornell Medical College

Kayvan Rahimi Keshari Assistant Professor of Biomedical Engineering in Radiology

Publications

selected publications

Background

education and training

Contact

full name