Wang, Michelle

Publications

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selected publications

Towards biological applications of nanophotonic tweezers. Current opinion in chemical biology. 2019 Review GET IT
Times cited: 15
Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity. Cell. 2019 Academic Article GET IT
Times cited: 32
High Trap Stiffness Microcylinders for Nanophotonic Trapping. ACS applied materials & interfaces. 2019 Academic Article GET IT
Times cited: 12
Molecular Highways-Navigating Collisions of DNA Motor Proteins. Journal of molecular biology. 2018 Review GET IT
Times cited: 8
Helicase promotes replication re-initiation from an RNA transcript. Nature communications. 2018 Academic Article GET IT
Times cited: 18
Single-Molecule Angular Optical Trapping for Studying Transcription Under Torsion. Methods in molecular biology (Clifton, N.J.). 2018 Academic Article GET IT
Times cited: 5
Mfd Dynamically Regulates Transcription via a Release and Catch-Up Mechanism. Cell. 2017 Academic Article GET IT
Times cited: 43
Nanophotonic trapping: precise manipulation and measurement of biomolecular arrays. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 2017 Review GET IT
Times cited: 26
Tunable nanophotonic array traps with enhanced force and stability. Optics express. 2017 Academic Article GET IT
Times cited: 8
DNA looping mediates nucleosome transfer. Nature communications. 2016 Academic Article GET IT
Times cited: 22
Single-Molecule Optical-Trapping Techniques to Study Molecular Mechanisms of a Replisome. Methods in enzymology. 2016 Academic Article GET IT
Times cited: 8
Biocompatible and High Stiffness Nanophotonic Trap Array for Precise and Versatile Manipulation. Nano letters. 2016 Academic Article GET IT
Times cited: 20
DNA supercoiling during transcription. Biophysical reviews. 2016 Academic Article GET IT
Times cited: 72
The Chd1 chromatin remodeler can sense both entry and exit sides of the nucleosome. Nucleic acids research. 2016 Academic Article GET IT
Times cited: 21
T7 replisome directly overcomes DNA damage. Nature communications. 2015 Academic Article GET IT
Times cited: 40
Single-molecule perspectives on helicase mechanisms and functions. Critical reviews in biochemistry and molecular biology. 2015 Review GET IT
Times cited: 28
Dynamic regulation of transcription factors by nucleosome remodeling. eLife. 2015 Academic Article GET IT
Times cited: 62
DNA Y structure: a versatile, multidimensional single molecule assay. Nano letters. 2014 Academic Article GET IT
Times cited: 23
Nanophotonic trapping for precise manipulation of biomolecular arrays. Nature nanotechnology. 2014 Academic Article GET IT
Times cited: 119
Discovering the power of single molecules. Cell. 2014 Review GET IT
Times cited: 11
Super-resolution microscopy reveals decondensed chromatin structure at transcription sites. Scientific reports. 2014 Academic Article GET IT
Times cited: 37
Interplay between DNA supercoiling and transcription elongation. Transcription. 2014 Academic Article GET IT
Times cited: 34
Small molecule injection into single-cell C. elegans embryos via carbon-reinforced nanopipettes. PloS one. 2013 Academic Article GET IT
Times cited: 8
Single-molecule unzipping force analysis of HU-DNA complexes. Chembiochem : a European journal of chemical biology. 2013 Academic Article GET IT
Times cited: 14
Transcription under torsion. Science (New York, N.Y.). 2013 Academic Article GET IT
Times cited: 207
Torque measurement at the single-molecule level. Annual review of biophysics. 2013 Review GET IT
Times cited: 63
Torque modulates nucleosome stability and facilitates H2A/H2B dimer loss. Nature communications. 2013 Academic Article GET IT
Times cited: 94
Biochemistry. A DNA twist diffuses and hops. Science (New York, N.Y.). 2012 Comment GET IT
Times cited: 5
Electro-optofluidics: achieving dynamic control on-chip. Optics express. 2012 Academic Article GET IT
Times cited: 25
Unzipping single DNA molecules to study nucleosome structure and dynamics. Methods in enzymology. 2012 Academic Article GET IT
Times cited: 21
Recent advances in single molecule studies of nucleosomes. Current opinion in structural biology. 2011 Review GET IT
Times cited: 43
ATP-induced helicase slippage reveals highly coordinated subunits. Nature. 2011 Academic Article GET IT
Times cited: 79
Underwound DNA under tension: structure, elasticity, and sequence-dependent behaviors. Physical review letters. 2011 Academic Article GET IT
Times cited: 81
Direct measurements of torque during Holliday junction migration. Biophysical journal. 2011 Letter GET IT
Times cited: 14
A257T linker region mutant of T7 helicase-primase protein is defective in DNA loading and rescued by T7 DNA polymerase. The Journal of biological chemistry. 2011 Academic Article GET IT
Times cited: 15
Structure and Scm3-mediated assembly of budding yeast centromeric nucleosomes. Nature communications. 2011 Academic Article GET IT
Times cited: 93
Comparison of Pause Predictions of Two Sequence-Dependent Transcription Models. Journal of statistical mechanics (Online). 2010 Academic Article GET IT
Times cited: 6
Passive torque wrench and angular position detection using a single-beam optical trap. Optics letters. 2010 Academic Article GET IT
Times cited: 30
Synergistic action of RNA polymerases in overcoming the nucleosomal barrier. Nature structural & molecular biology. 2010 Academic Article GET IT
Times cited: 101
Discontinuities at the DNA supercoiling transition. Physical review. E, Statistical, nonlinear, and soft matter physics. 2009 Academic Article GET IT
Times cited: 31
Twist-stretch coupling and phase transition during DNA supercoiling. Physical chemistry chemical physics : PCCP. 2009 Academic Article GET IT
Times cited: 47
High-resolution dynamic mapping of histone-DNA interactions in a nucleosome. Nature structural & molecular biology. 2009 Academic Article GET IT
Times cited: 297
A biophysicist marvels at the idea of grabbing microscopic particles with light by tweaking its phase. Nature. 2008 Academic Article GET IT
Abrupt buckling transition observed during the plectoneme formation of individual DNA molecules. Physical review letters. 2008 Academic Article GET IT
Times cited: 161
Single-molecule studies reveal dynamics of DNA unwinding by the ring-shaped T7 helicase. Cell. 2007 Academic Article GET IT
Times cited: 199
Nanofabricated quartz cylinders for angular trapping: DNA supercoiling torque detection. Nature methods. 2007 Academic Article GET IT
Times cited: 139
Mechanochemical kinetics of transcription elongation. Physical review letters. 2007 Academic Article GET IT
Times cited: 64
Probing SWI/SNF remodeling of the nucleosome by unzipping single DNA molecules. Nature structural & molecular biology. 2006 Academic Article GET IT
Times cited: 86
Single-molecule analysis of RNA polymerase transcription. Annual review of biophysics and biomolecular structure. 2006 Review GET IT
Times cited: 99
Detection of high-affinity and sliding clamp modes for MSH2-MSH6 by single-molecule unzipping force analysis. Molecular cell. 2005 Academic Article GET IT
Times cited: 48
Detection of forces and displacements along the axial direction in an optical trap. Biophysical journal. 2005 Academic Article GET IT
Times cited: 44
Specific contributions of histone tails and their acetylation to the mechanical stability of nucleosomes. Journal of molecular biology. 2004 Academic Article GET IT
Times cited: 152
Sequence-dependent kinetic model for transcription elongation by RNA polymerase. Journal of molecular biology. 2004 Academic Article GET IT
Times cited: 125
A single-molecule technique to study sequence-dependent transcription pausing. Biophysical journal. 2004 Academic Article GET IT
Times cited: 45
Molecular mechanism of transcription inhibition by peptide antibiotic Microcin J25. Molecular cell. 2004 Academic Article GET IT
Times cited: 138
Optical torque wrench: angular trapping, rotation, and torque detection of quartz microparticles. Physical review letters. 2004 Academic Article GET IT
Times cited: 303
Use of optical trapping techniques to study single-nucleosome dynamics. Methods in enzymology. 2004 Review GET IT
Times cited: 20
Dynamic force spectroscopy of protein-DNA interactions by unzipping DNA. Physical review letters. 2003 Academic Article GET IT
Times cited: 77
Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior. Proceedings of the National Academy of Sciences of the United States of America. 2002 Academic Article GET IT
Times cited: 156
Probing protein-DNA interactions by unzipping a single DNA double helix. Biophysical journal. 2002 Academic Article GET IT
Times cited: 111
Mechanical disruption of individual nucleosomes reveals a reversible multistage release of DNA. Proceedings of the National Academy of Sciences of the United States of America. 2002 Academic Article GET IT
Times cited: 392
Stretching of single collapsed DNA molecules. Biophysical journal. 2000 Academic Article GET IT
Times cited: 227
Manipulation of single molecules in biology. Current opinion in biotechnology. 1999 Review GET IT
Times cited: 37
Estimating the persistence length of a worm-like chain molecule from force-extension measurements. Biophysical journal. 1999 Academic Article GET IT
Times cited: 542
Force and velocity measured for single molecules of RNA polymerase. Science (New York, N.Y.). 1998 Academic Article GET IT
Times cited: 753
Stretching DNA with optical tweezers. Biophysical journal. 1997 Academic Article GET IT
Times cited: 1178
Transcription against an applied force. Science (New York, N.Y.). 1995 Academic Article GET IT
Times cited: 485

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Background

education and training

Ph.D., University of Michigan 1993
M.S., University of Southern Mississippi 1988
B.S., Nanjing University (China) 1985

Contact

full name

Michelle Wang

VIVO Weill Cornell Medical College

Michelle Wang Professor of Physics in Cell and Developmental Biology

Publications

selected publications

Background

education and training

Contact

full name