selected publications
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Design and rationale for the life after stopping tyrosine kinase inhibitors (LAST) study, a prospective, single-group longitudinal study in patients with chronic myeloid leukemia.
BMC cancer.
2018
Academic Article
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Times cited: 14 - Running the marathon of chronic myeloid leukemia with no shoes (or without the right shoes)!. Cancer. 2017 Editorial Article GET IT
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Overall survival with ponatinib versus allogeneic stem cell transplantation in Philadelphia chromosome-positive leukemias with the T315I mutation.
Cancer.
2017
Academic Article
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Times cited: 71 -
Can any patients with chronic myeloid leukemia outside of a clinical trial have their tyrosine kinase inhibitor discontinued?.
Current opinion in hematology.
2017
Review
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Times cited: 1 - Chronic myeloid leukemia: Is it dusk or dawn?. Best practice & research. Clinical haematology. 2016 Editorial Article GET IT
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Pleural Effusion in Dasatinib-Treated Patients With Chronic Myeloid Leukemia in Chronic Phase: Identification and Management.
Clinical lymphoma, myeloma & leukemia.
2016
Review
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Times cited: 56 -
Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis.
The New England journal of medicine.
2016
Academic Article
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Times cited: 332 -
Acute myeloid leukemia masquerading as hepatocellular carcinoma.
2016
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Times cited: 322 -
Long-term evaluation of cardiac and vascular toxicity in patients with Philadelphia chromosome-positive leukemias treated with bosutinib.
American journal of hematology.
2016
Academic Article
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Times cited: 62 -
Cross-Intolerance With Dasatinib Among Imatinib-Intolerant Patients With Chronic Phase Chronic Myeloid Leukemia.
Clinical lymphoma, myeloma & leukemia.
2016
Academic Article
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Times cited: 10 -
Evaluating the Impact of a Switch to Nilotinib on Imatinib-Related Chronic Low-Grade Adverse Events in Patients With CML-CP: The ENRICH Study.
Clinical lymphoma, myeloma & leukemia.
2016
Academic Article
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Times cited: 28 -
Clinical features of pulmonary arterial hypertension in patients receiving dasatinib.
American journal of hematology.
2015
Review
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Times cited: 90 -
BCR-ABL1 mutation development during first-line treatment with dasatinib or imatinib for chronic myeloid leukemia in chronic phase.
Leukemia.
2015
Academic Article
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Times cited: 52 -
The role of observational studies in optimizing the clinical management of chronic myeloid leukemia.
Therapeutic advances in hematology.
2015
Review
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Times cited: 20 -
Cardiovascular and pulmonary adverse events in patients treated with BCR-ABL inhibitors: Data from the FDA Adverse Event Reporting System.
American journal of hematology.
2015
Academic Article
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Times cited: 46 -
Goals for chronic myeloid leukemia TK inhibitor treatment: how little disease is too much?.
Hematology. American Society of Hematology. Education Program.
2014
Review
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Times cited: 5 -
Prognostic significance of early molecular response in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors.
2014
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Times cited: 5 - Extending the reach of nilotinib in chronic myeloid leukemia. Haematologica. 2014 Editorial Article GET IT
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Integrating current treatment options for TKI-resistant chronic myeloid leukemia.
Clinical advances in hematology & oncology : H&O.
2014
Academic Article
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Times cited: 2 - The challenge of the 'C' in CML. Leukemia research. 2013 Editorial Article GET IT
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Pityriasis rubra pilaris-like eruption associated with the multikinase inhibitor ponatinib.
Journal of the American Academy of Dermatology.
2013
Letter
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Times cited: 18 -
Sequential therapy in chronic myelogenous leukemia: where do emerging therapies fit within current treatment regimens?.
Clinical advances in hematology & oncology : H&O.
2013
Review
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Times cited: 1 -
Striving to achieve safe, permanent treatment discontinuation in chronic myeloid leukemia.
Leukemia research.
2013
Review
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Times cited: 8 - Editorial. Therapeutic advances in hematology. 2013 Academic Article GET IT
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The BCR-ABLT315I mutation compromises survival in chronic phase chronic myelogenous leukemia patients resistant to tyrosine kinase inhibitors, in a matched pair analysis.
Haematologica.
2013
Academic Article
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Times cited: 47 -
Ponatinib in patients with refractory acute myeloid leukaemia: findings from a phase 1 study.
British journal of haematology.
2013
Letter
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Times cited: 53 -
T315I, more or less, predicts for major molecular response: the devil is in the details!.
Haematologica.
2013
Editorial Article
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Times cited: 2 -
Analysis of the potential effect of ponatinib on the QTc interval in patients with refractory hematological malignancies.
Cancer chemotherapy and pharmacology.
2013
Academic Article
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Times cited: 19 - Editorial. Therapeutic advances in hematology. 2013 Academic Article GET IT
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Predictive factors for successful imatinib cessation in chronic myeloid leukemia patients treated with imatinib.
American journal of hematology.
2013
Academic Article
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Times cited: 51 -
Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or non-tyrosine kinase therapy: a retrospective cohort analysis.
Leukemia.
2013
Academic Article
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Times cited: 173 - Editorial. Therapeutic advances in hematology. 2013 Academic Article GET IT
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Overcoming resistance in chronic myelogenous leukemia.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.
2013
Review
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Times cited: 1 -
Advances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop.
Leukemia & lymphoma.
2012
Review
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Times cited: 10 -
Ponatinib in refractory Philadelphia chromosome-positive leukemias.
The New England journal of medicine.
2012
Academic Article
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Times cited: 603 -
Current practices in the management of chronic myeloid leukemia.
Clinical lymphoma, myeloma & leukemia.
2012
Academic Article
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Times cited: 10 -
Clinical roundtable monograph: Emerging treatment options for TKI-resistant chronic myelogenous leukemia.
Clinical advances in hematology & oncology : H&O.
2012
Academic Article
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Times cited: 7 - Editorial. Therapeutic advances in hematology. 2012 Academic Article GET IT
- Editorial. Therapeutic advances in hematology. 2012 Academic Article GET IT
- Editorial. Therapeutic advances in hematology. 2012 Academic Article GET IT
- Editorial. Therapeutic advances in hematology. 2012 Academic Article GET IT
- Editorial. Therapeutic advances in hematology. 2012 Academic Article GET IT
- Editorial. Therapeutic advances in hematology. 2011 Academic Article GET IT
- Editorial. Therapeutic advances in hematology. 2011 Academic Article GET IT
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Will imatinib compromise reproductive capacity?
2011
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Times cited: 44 -
Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias.
Blood.
2011
Academic Article
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Times cited: 51 - Editorial. Therapeutic advances in hematology. 2011 Academic Article GET IT
- Editorial. Therapeutic advances in hematology. 2011 Academic Article GET IT
- Editorial. Therapeutic advances in hematology. 2011 Academic Article GET IT
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Practical management of patients with chronic myeloid leukemia.
Cancer.
2011
Review
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Times cited: 23 - Editorial. Therapeutic advances in hematology. 2011 Academic Article GET IT
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Intolerance to tyrosine kinase inhibitors in chronic myeloid leukemia: Definitions and clinical implications.
Cancer.
2010
Review
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Times cited: 52 - Editorial. Therapeutic advances in hematology. 2010 Academic Article GET IT
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Epidemiologic study on survival of chronic myeloid leukemia and Ph(+) acute lymphoblastic leukemia patients with BCR-ABL T315I mutation.
Blood.
2009
Academic Article
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Times cited: 99 -
Management of drug toxicities in chronic myeloid leukaemia.
Best practice & research. Clinical haematology.
2009
Review
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Times cited: 40 -
Determining the rise in BCR-ABL RNA that optimally predicts a kinase domain mutation in patients with chronic myeloid leukemia on imatinib.
Blood.
2009
Academic Article
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Times cited: 67 -
Response dynamics in chronic-phase chronic myeloid leukemia.
Clinical lymphoma & myeloma.
2009
Review
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Times cited: 1 -
Tailoring tyrosine kinase inhibitor therapy in chronic myeloid leukemia.
Cancer control : journal of the Moffitt Cancer Center.
2009
Review
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Times cited: 7 -
Appropriate sequencing of tyrosine kinase inhibitors in chronic myelogenous leukemia: when to change? A perspective in 2009.
Current opinion in hematology.
2009
Review
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Times cited: 6 -
An activating KRAS mutation in imatinib-resistant chronic myeloid leukemia.
Leukemia.
2008
Letter
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Times cited: 30 -
An intron-derived insertion/truncation mutation in the BCR-ABL kinase domain in chronic myeloid leukemia patients undergoing kinase inhibitor therapy.
2008
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Times cited: 53 -
Optimizing outcomes for patients with advanced disease in chronic myelogenous leukemia.
Seminars in oncology.
2008
Review
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Times cited: 28 -
A half-log increase in BCR-ABL RNA predicts a higher risk of relapse in patients with chronic myeloid leukemia with an imatinib-induced complete cytogenetic response.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2007
Academic Article
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Times cited: 111 -
Mutational analysis and overcoming imatinib resistance in chronic myeloid leukemia with novel tyrosine kinase inhibitors.
Current treatment options in oncology.
2007
Review
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Times cited: 1 -
Mutations of the BCR-ABL-kinase domain occur in a minority of patients with stable complete cytogenetic response to imatinib.
Leukemia.
2007
Academic Article
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Times cited: 73 - Stem cell transplantation in patients with chronic myelogenous leukemia: when should it be used?. Mayo Clinic proceedings. 2006 Review GET IT
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BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate-treated patients with CML.
Blood.
2006
Academic Article
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Times cited: 111 -
Chronic myeloid leukemia in 2006: a perspective.
Haematologica.
2006
Editorial Article
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Times cited: 55 -
Defining and managing imatinib resistance.
Hematology. American Society of Hematology. Education Program.
2006
Review
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Times cited: 79 - Baseline disease risk and response to therapy in chronic myeloid leukemia: necessary predictive tools then and now. Haematologica. 2005 Comment GET IT
- Chronic myeloid leukemia: current application of cytogenetics and molecular testing for diagnosis and treatment. Mayo Clinic proceedings. 2005 Review GET IT
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Ph-positive and -negative myeloproliferative syndromes may co-exist.
Leukemia.
2004
Letter
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Times cited: 7 -
Divergent clinical outcome in two CML patients who discontinued imatinib therapy after achieving a molecular remission.
2004
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Times cited: 117 -
Thienopyridine-linked thrombotic microangiopathy: association with endothelial cell apoptosis and activation of MAP kinase signalling cascades.
British journal of haematology.
2004
Academic Article
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Times cited: 35 -
Clonal evolution and lack of cytogenetic response are adverse prognostic factors for hematologic relapse of chronic phase CML patients treated with imatinib mesylate.
Blood.
2003
Academic Article
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Times cited: 101 -
Transplantation for chronic myelogenous leukemia: yes, no, maybe so. . . An Oregon perspective.
Bone marrow transplantation.
2003
Review
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Times cited: 15 -
Images in clinical medicine. Hyperleukocytosis in acute myeloid leukemia.
2003
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Times cited: 3 -
In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines.
Blood.
2003
Academic Article
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Times cited: 85 -
STI571 as a targeted therapy for CML.
Cancer investigation.
2003
Review
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Times cited: 54 -
Demonstration of Philadelphia chromosome negative abnormal clones in patients with chronic myelogenous leukemia during major cytogenetic responses induced by imatinib mesylate.
Leukemia.
2003
Academic Article
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Times cited: 103 -
The impact of clonal evolution on response to imatinib mesylate (STI571) in accelerated phase CML.
Blood.
2002
Academic Article
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Times cited: 118 -
Hematopathologic and cytogenetic findings in imatinib mesylate-treated chronic myelogenous leukemia patients: 14 months' experience.
Blood.
2002
Academic Article
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Times cited: 94 -
Recent advancements in the treatment of chronic myelogenous leukemia.
Annual review of medicine.
2002
Review
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Times cited: 58 -
STI571: a paradigm of new agents for cancer therapeutics.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2002
Review
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Times cited: 200 -
ST1571, a tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia: validating the promise of molecularly targeted therapy.
Cancer chemotherapy and pharmacology.
2001
Academic Article
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Times cited: 29 -
STI571: a gene product-targeted therapy for leukemia.
Current oncology reports.
2001
Review
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Times cited: 35 -
Chronic myelogenous leukemia.
Current opinion in oncology.
2001
Review
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Times cited: 81 -
Role of transforming growth factor beta1 in microvascular endothelial cell apoptosis associated with thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome.
American journal of hematology.
2001
Academic Article
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Times cited: 19 -
STI571: targeting BCR-ABL as therapy for CML.
The oncologist.
2001
Review
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Times cited: 193