Kasi, Pashtoon

Publications

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selected publications

Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study. The Lancet. Oncology. 2023 Academic Article GET IT
Types of Liquid Biopsies: Understanding the Different Lenses Through Which They Can Detect Cancer. The oncologist. 2023 Comment GET IT
Using Tumor-Informed Circulating Tumor DNA (ctDNA)-Based Testing for Patients with Anal Squamous Cell Carcinoma. The oncologist. 2023 Academic Article GET IT
DPYD Testing: Time to Put Patient Safety First. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2023 Academic Article GET IT
Times cited: 2
Genetic features and therapeutic relevance of emergent circulating tumor DNA alterations in refractory non-colorectal gastrointestinal cancers. Nature communications. 2022 Academic Article GET IT
Times cited: 1
Analysis of Circulating Tumor DNA to Predict Risk of Recurrence in Patients With Esophageal and Gastric Cancers. JCO precision oncology. 2022 Academic Article GET IT
Peptide Receptor Radionuclide Therapy in Merkel Cell Carcinoma: A Comprehensive Review. Journal of nuclear medicine technology. 2022 Review GET IT
Times cited: 1
Liquid biopsies and tumor mutational burden: the cutoff conundrum. Nature medicine. 2022 Comment GET IT
Using Circulating Tumor DNA in Colorectal Cancer: Current and Evolving Practices. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Review GET IT
Times cited: 17
Larotrectinib in Mismatch-Repair-Deficient TRK Fusion-Positive Metastatic Colon Cancer After Progression on Immunotherapy. 2022 GET IT
Reply to F. Dayyani et al. JCO precision oncology. 2022 Comment GET IT
Circulating Tumor DNA in Identifying Resistant Sub-Clones Post EGFR Blockade: Implications for EGFR Rechallenge. Frontiers in oncology. 2022 Academic Article GET IT
Times cited: 2
Detection of microsatellite instability-high (MSI-H) by liquid biopsy predicts robust and durable response to immunotherapy in patients with pancreatic cancer. Journal for immunotherapy of cancer. 2022 Academic Article GET IT
Times cited: 6
BESPOKE IO protocol: a multicentre, prospective observational study evaluating the utility of ctDNA in guiding immunotherapy in patients with advanced solid tumours. BMJ open. 2022 Academic Article GET IT
Times cited: 2
Call for Adoption of Synchronized Biweekly Dosing of Anti-EGFR Agent Cetuximab: Implications for Patients with Metastatic Colorectal Cancer, and Squamous Cell Carcinoma of the Head and Neck. The oncologist. 2022 Comment GET IT
Epidermal Growth Factor Receptor Inhibition in Epidermal Growth Factor Receptor-Amplified Gastroesophageal Cancer: Retrospective Global Experience. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Academic Article GET IT
Times cited: 2
Beyond Circulating Tumor Cell Enumeration: Cell-Based Liquid Biopsy to Assess Protein Biomarkers and Cancer Genomics Using the RareCyte^® Platform. Frontiers in pharmacology. 2022 Academic Article GET IT
Times cited: 4
Impact of Circulating Tumor DNA-Based Detection of Molecular Residual Disease on the Conduct and Design of Clinical Trials for Solid Tumors. JCO precision oncology. 2022 Review GET IT
Times cited: 16
Circulating tumor DNA (ctDNA) serial analysis during progression on PD-1 blockade and later CTLA-4 rescue in patients with mismatch repair deficient metastatic colorectal cancer. 2022 GET IT
Times cited: 10
Tumor-Informed Versus Plasma-Only Liquid Biopsy Assay in a Patient With Multiple Primary Malignancies. 2022 GET IT
Deploying an artificial intelligence-based online search tool to increase patients' access to and understanding of solid tumor gastrointestinal clinical trials. Journal of gastrointestinal oncology. 2021 Academic Article GET IT
Times cited: 10737
BESPOKE study protocol: a multicentre, prospective observational study to evaluate the impact of circulating tumour DNA guided therapy on patients with colorectal cancer. BMJ open. 2021 Academic Article GET IT
Times cited: 8
A Phase II Trial of Adjuvant Durvalumab Following Trimodality Therapy for Locally Advanced Esophageal and Gastroesophageal Junction Adenocarcinoma: A Big Ten Cancer Research Consortium Study. Frontiers in oncology. 2021 Academic Article GET IT
Times cited: 970
Treatment Holidays for Patients With Metastatic Colorectal Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2021 Editorial Article GET IT
Times cited: 1
Microsatellite Instability-High, Malignant Insulinoma With Brain Metastasis. 2021 GET IT
Author Correction: COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials. Nature reviews. Clinical oncology. 2021 Article GET IT
Times cited: 3
Outcomes on anti-VEGFR-2/paclitaxel treatment after progression on immune checkpoint inhibition in patients with metastatic gastroesophageal adenocarcinoma. International journal of cancer. 2021 Academic Article GET IT
Times cited: 11
COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials. 2021 GET IT
Times cited: 91
Circulating Tumor DNA-Based Testing and Actionable Findings in Patients with Advanced and Metastatic Pancreatic Adenocarcinoma. The oncologist. 2021 Academic Article GET IT
Times cited: 19
Effect of Germline Mutations in Homologous Recombination Repair Genes on Overall Survival of Patients with Pancreatic Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 21
Retrospective review of outcomes in patients with DNA-damage repair related pancreatic cancer. Hereditary cancer in clinical practice. 2020 Academic Article GET IT
Times cited: 38
Favorable Outcomes in FGFR Fusion-Positive Cholangiocarcinomas and Evolution on Treatment Noted on Circulating Tumor DNA Liquid Biopsies. 2020 GET IT
Times cited: 7
Circulating tumor DNA and plasma microsatellite instability during PD-1 blockade. Journal of gastrointestinal oncology. 2020 Academic Article GET IT
Times cited: 5
Peritoneal Cell-Free Tumor DNA as Biomarker for Peritoneal Surface Malignancies. Annals of surgical oncology. 2020 Academic Article GET IT
Times cited: 11
Blood-based next-generation sequencing analysis of neuroendocrine neoplasms. Oncotarget. 2020 Academic Article GET IT
Times cited: 22
BRAF-V600E and microsatellite instability prediction through CA-19-9/CEA ratio in patients with colorectal cancer. Journal of gastrointestinal oncology. 2020 Academic Article GET IT
Times cited: 62
Circulating Tumor DNA-Based Detection of Microsatellite Instability and Response to Immunotherapy in Pancreatic Cancer. 2020 GET IT
Times cited: 4
Should we optimize cytotoxic therapy by dosing to neutropenia? Lessons from TAS-102. Annals of oncology : official journal of the European Society for Medical Oncology. 2020 Editorial Article GET IT
Times cited: 2
Circulating Tumor DNA Profiling of Advanced Biliary Tract Cancers. JCO precision oncology. 2019 Academic Article GET IT
Times cited: 46
Binimetinib, encorafenib and cetuximab (BEACON Trial) combination therapy for patients with BRAF V600E-mutant metastatic colorectal cancer. Drugs of today (Barcelona, Spain : 1998). 2019 Review GET IT
Times cited: 8
Colorectal cancer. Lancet (London, England). 2019 Review GET IT
Times cited: 1744
Trastuzumab and pertuzumab in circulating tumor DNA ERBB2-amplified HER2-positive refractory cholangiocarcinoma. 2019 GET IT
Times cited: 30
Dramatic response to modified docetaxel, cisplatin, and fluorouracil chemotherapy after immunotherapy in a patient with refractory metastatic anal cancer. 2019 GET IT
Times cited: 2
Validation of Microsatellite Instability Detection Using a Comprehensive Plasma-Based Genotyping Panel. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 107
Feasibility of circulating tumor DNA testing in hepatocellular carcinoma. Journal of gastrointestinal oncology. 2019 Academic Article GET IT
Times cited: 58
Feasibility and clinical value of circulating tumor DNA testing in patients with gastric adenocarcinomas. Journal of gastrointestinal oncology. 2019 Academic Article GET IT
Times cited: 8
Role of Circulating Tumor DNA in Gastrointestinal Cancers: Update From Abstracts and Sessions at ASCO 2018. Frontiers in oncology. 2019 Academic Article GET IT
Times cited: 7
Colorectal Cancer Characteristics and Outcomes after Solid Organ Transplantation. Journal of oncology. 2019 Academic Article GET IT
Times cited: 32
Impact of Tumor Location and Variables Associated With Overall Survival in Patients With Colorectal Cancer: A Mayo Clinic Colon and Rectal Cancer Registry Study. Frontiers in oncology. 2019 Academic Article GET IT
Times cited: 1054
Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence. 2019 GET IT
Times cited: 363
Expanding the Indication for Novel Theranostic 177Lu-Dotatate Peptide Receptor Radionuclide Therapy: Proof-of-Concept of PRRT in Merkel Cell Cancer. 2019 GET IT
Times cited: 8
A Care Process Model to Deliver ¹⁷⁷Lu-Dotatate Peptide Receptor Radionuclide Therapy for Patients With Neuroendocrine Tumors. Frontiers in oncology. 2019 Academic Article GET IT
Times cited: 46
Feasibility of Integrating Panel-Based Pharmacogenomics Testing for Chemotherapy and Supportive Care in Patients With Colorectal Cancer. Technology in cancer research & treatment. 2019 Academic Article GET IT
Times cited: 10
Body Mass Index and Long-Term Outcomes in Patients With Colorectal Cancer. Frontiers in oncology. 2018 Academic Article GET IT
Times cited: 687
Disparities in minimally invasive surgery for colorectal cancer in Florida. American journal of surgery. 2018 Academic Article GET IT
Times cited: 9
Clinical Value of Pharmacogenomic Testing in a Patient Receiving FOLFIRINOX for Pancreatic Adenocarcinoma. Frontiers in pharmacology. 2018 Academic Article GET IT
Times cited: 30
Rising Proportion of Young Individuals With Rectal and Colon Cancer. Clinical colorectal cancer. 2018 Academic Article GET IT
Times cited: 74
Trends and outcomes of sphincter-preserving surgery for rectal cancer: a national cancer database study. International journal of colorectal disease. 2018 Academic Article GET IT
Times cited: 16
Incidence of Pathogenic Variants in Those With a Family History of Pancreatic Cancer. Frontiers in oncology. 2018 Academic Article GET IT
Times cited: 23
Uridine triacetate for severe 5-fluorouracil toxicity in a patient with thymidylate synthase gene variation: Potential pharmacogenomic implications. 2018 GET IT
BRCA Mutation and Its Association With Colorectal Cancer. 2018 GET IT
Times cited: 20
Telotristat ethyl for the treatment of carcinoid syndrome diarrhea not controlled by somatostatin analogues. Drugs of today (Barcelona, Spain : 1998). 2018 Review GET IT
Times cited: 2
Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer. JAMA. 2018 Academic Article GET IT
Times cited: 309
Robotic-assisted cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC). 2018 GET IT
Times cited: 9
Chemotherapy-Induced Neutropenia as a Prognostic and Predictive Marker of Outcomes in Solid-Tumor Patients. Drugs. 2018 Review GET IT
Times cited: 28
Exceptional response to everolimus in a novel tuberous sclerosis complex-2 mutation-associated metastatic renal-cell carcinoma. 2018 GET IT
Times cited: 13
Folate Receptor Alpha Peptide Vaccine Generates Immunity in Breast and Ovarian Cancer Patients. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 48
Telotristat Ethyl for Patients With Carcinoid Syndrome Associated With Chest Pain and Hypertension. 2018 GET IT
Times cited: 3
Neuroendocrine Tumor Involving the Epicardium. 2017 GET IT
Times cited: 1
Mutational burden on circulating cell-free tumor-DNA testing as a surrogate marker of mismatch repair deficiency or microsatellite instability in patients with colorectal cancers. Journal of gastrointestinal oncology. 2017 Academic Article GET IT
Times cited: 6445
The Feasibility and Safety of Surgery in Patients Receiving Immune Checkpoint Inhibitors: A Retrospective Study. Frontiers in oncology. 2017 Academic Article GET IT
Times cited: 33
^Non-V600 BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2017 Academic Article GET IT
Times cited: 212
A proof-of-concept trial of protein kinase C iota inhibition with auranofin for the paclitaxel-induced acute pain syndrome. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2016 Academic Article GET IT
Times cited: 7
Chemotherapy induced neutropenia at 1-month mark is a predictor of overall survival in patients receiving TAS-102 for refractory metastatic colorectal cancer: a cohort study. BMC cancer. 2016 Academic Article GET IT
Times cited: 56
Molecular Biomarkers in the Personalized Treatment of Colorectal Cancer. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2016 Review GET IT
Times cited: 92
Associations of microbiota and toll-like receptor signaling pathway in esophageal adenocarcinoma. BMC cancer. 2016 Academic Article GET IT
Times cited: 65
Unilateral Arm Urticaria Presenting as a Paraneoplastic Manifestation of Metachronous Bilateral Breast Cancer. 2016 GET IT
Times cited: 5
Clonal evolution of AML on novel FMS-like tyrosine kinase-3 (FLT3) inhibitor therapy with evolving actionable targets. 2016 GET IT
Times cited: 15
Chemotherapy Maintenance. Cancer journal (Sudbury, Mass.). 2016 Review GET IT
Times cited: 26
Treatment of HIV/AIDS associated cancers with immunotherapy targeting PD-1/PD-L1 instead of chemotherapy. Medical hypotheses. 2015 Academic Article GET IT
Times cited: 1
Should Vital Signs Be Routinely Obtained Prior to Intravenous Chemotherapy? Results From a 2-Center Study. Cancer control : journal of the Moffitt Cancer Center. 2015 Academic Article GET IT
Transition of Care for Inpatient Hematology Patients Receiving Chemotherapy: Development of Hospital Discharge Huddle Process and Effects of Implementation. Journal of oncology practice. 2015 Academic Article GET IT
Times cited: 8
Is obesity an advantage in patients with colorectal cancer?. Expert review of gastroenterology & hepatology. 2015 Editorial Article GET IT
Times cited: 18
BRCA2-associated pancreatic cancer and current screening guidelines. Cancer. 2015 Letter GET IT
Times cited: 3
Chemotherapy in the Setting of Severe Liver Dysfunction in Patients with Metastatic Colorectal Cancer. Case reports in oncological medicine. 2015 Academic Article GET IT
Times cited: 75
MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model. PloS one. 2015 Academic Article GET IT
Times cited: 11
Nelarabine associated myotoxicity and rhabdomyolysis. Case reports in hematology. 2015 Academic Article GET IT
Times cited: 252
Selection of biologics for patients with metastatic colorectal cancer: the role of predictive markers. Expert review of gastroenterology & hepatology. 2015 Editorial Article GET IT
Times cited: 8
Waldenström macroglobulinemia. Clinical advances in hematology & oncology : H&O. 2015 Review GET IT
Times cited: 14
Evaluation of a 4-protein serum biomarker panel-biglycan, annexin-A6, myeloperoxidase, and protein S100-A9 (B-AMP)-for the detection of esophageal adenocarcinoma. Cancer. 2014 Academic Article GET IT
Times cited: 35
Establishing magnetic resonance imaging as an accurate and reliable tool to diagnose and monitor esophageal cancer in a rat model. PloS one. 2014 Academic Article GET IT
Times cited: 7
Safety of pegfilgrastim (neulasta) in patients with sickle cell trait/anemia. Case reports in hematology. 2013 Academic Article GET IT
Prognostic value and targeted inhibition of survivin expression in esophageal adenocarcinoma and cancer-adjacent squamous epithelium. PloS one. 2013 Academic Article GET IT
Times cited: 21
The use of intravenous neostigmine in palliation of severe ileus. Case reports in gastrointestinal medicine. 2013 Academic Article GET IT
Clinical manifestations and diagnostic challenges in acute porphyrias. Case reports in hematology. 2013 Academic Article GET IT
Clinical review: Serious adverse events associated with the use of rituximab - a critical care perspective. Critical care (London, England). 2012 Review GET IT
Times cited: 119
Aortic dissection and renal failure in a patient with severe hypothyroidism. Case reports in medicine. 2012 Academic Article GET IT
Times cited: 4
Correlates of morbidity and mortality in severe necrotizing pancreatitis. ISRN surgery. 2012 Academic Article GET IT
Coping styles in patients with anxiety and depression. ISRN psychiatry. 2012 Academic Article GET IT
Proposing the use of hyponatremia as a marker to help identify high risk individuals for lung cancer. Medical hypotheses. 2012 Academic Article GET IT
Times cited: 8
The role of fine-needle aspiration cytology in the diagnosis of Basal cell carcinoma. ISRN dermatology. 2012 Academic Article GET IT
Rituximab and cytokine release syndrome. 2012 GET IT
Times cited: 31
Gallbladder agenesis. 2011 GET IT
Times cited: 32
Malignant Hyperthermia and Idiopathic HyperCKemia. 2011 GET IT
Times cited: 6
Clinical manifestations and distribution of cutaneous leishmaniasis in pakistan. Journal of tropical medicine. 2011 Academic Article GET IT
Times cited: 27
Incidence, management, and outcome of molar pregnancies at a tertiary care hospital in quetta, pakistan. ISRN obstetrics and gynecology. 2011 Academic Article GET IT
Experience of emergency peripartum hysterectomies at a tertiary care hospital in quetta, pakistan. ISRN obstetrics and gynecology. 2011 Academic Article GET IT
Birt-hogg-dubé syndrome: answering questions raised by a case report published in 1962. 2011 GET IT
Times cited: 2
Cardiovascular side effects of atomoxetine and its interactions with inhibitors of the cytochrome p450 system. 2011 GET IT
Times cited: 14
Thrombotic thrombocytopenic purpura and gemcitabine. 2011 GET IT
Times cited: 7
Determining the risk factors and prevalence of osteoporosis using quantitative ultrasonography in Pakistani adult women. Singapore medical journal. 2009 Academic Article GET IT
Times cited: 29
Marring leishmaniasis: the stigmatization and the impact of cutaneous leishmaniasis in Pakistan and Afghanistan. PLoS neglected tropical diseases. 2008 Academic Article GET IT
Times cited: 109
Quintuplets born to a woman without fertility treatment in Pakistan. 2008 GET IT
Times cited: 2
Vector control in cutaneous leishmaniasis of the old world: a review of literature. Dermatology online journal. 2008 Review GET IT
Times cited: 19
Outcome of triple procedure in older children with developmental dysplasia of hip (DDH). JPMA. The Journal of the Pakistan Medical Association. 2007 Academic Article GET IT
Times cited: 20
Factors influencing medical student participation in an obstetrics and gynaecology clinic. JPMA. The Journal of the Pakistan Medical Association. 2007 Academic Article GET IT
Times cited: 4
Excessive work hours of physicians in training: maladaptive coping strategies. PLoS medicine. 2007 Letter GET IT
Times cited: 6
Epilepsy: public knowledge and attitude in a slum area of Karachi, Pakistan. Seizure. 2007 Academic Article GET IT
Times cited: 33
Seroprevalences and co-infections of HIV, hepatitis C virus and hepatitis B virus in injecting drug users in Quetta, Pakistan. Tropical doctor. 2007 Academic Article GET IT
Times cited: 29
Studying the association between postgraduate trainees' work hours, stress and the use of maladaptive coping strategies. Journal of Ayub Medical College, Abbottabad : JAMC. 2007 Academic Article GET IT
Times cited: 15
Using choriocarcinoma to cause remission of other tumors: a novel approach to kill tumors. Medical hypotheses. 2006 Letter GET IT
Acute health effects of the Tasman Spirit oil spill on residents of Karachi, Pakistan. BMC public health. 2006 Academic Article GET IT
Times cited: 58
Psychiatric health laws in Pakistan: from lunacy to mental health. PLoS medicine. 2005 Academic Article GET IT
Times cited: 16
Diagnosis of cutaneous leishmaniasis by fine needle aspiration cytology: a report of 66 cases. Tropical doctor. 2005 Letter GET IT
Times cited: 7
Blinding trachoma: a disease of poverty. PLoS medicine. 2004 Review GET IT
Times cited: 30
Trachoma still ignored in developing countries. Lancet (London, England). 2004 Letter GET IT
Times cited: 6
Improvement of water and sanitation for developing countries. Lancet (London, England). 2004 Letter GET IT
Times cited: 1
Fine-needle aspiration cytology in the diagnosis of cutaneous leishmaniasis. Annals of Saudi medicine. 2004 Academic Article GET IT
Times cited: 25

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Background

education and training

M.S., Mayo Graduate School 2018
M.B.,B.S., Aga Khan University Medical College, Karachi (Pakistan) 2006

Contact

full name

Pashtoon Kasi

primary email

pmk4001@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Pashtoon Kasi Assistant Professor of Medicine (Interim)

Publications

selected publications

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email

webpage