Singer, Samuel

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selected publications

Association of MRI T2 Signal Intensity With Desmoid Tumor Progression During Active Observation: A Retrospective Cohort Study. Annals of surgery. 2020 Academic Article GET IT
Times cited: 34
Rb and p53-Deficient Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma Require Skp2 for Survival. Cancer research. 2020 Comment GET IT
Times cited: 19
Objective Response Rate Among Patients With Locally Advanced or Metastatic Sarcoma Treated With Talimogene Laherparepvec in Combination With Pembrolizumab: A Phase 2 Clinical Trial. JAMA oncology. 2020 Academic Article GET IT
Times cited: 92
Pan-cancer analysis of whole genomes. Nature. 2020 Academic Article GET IT
Times cited: 1201
Prognostic stratification of clinical and molecular epithelioid hemangioendothelioma subsets. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2019 Academic Article GET IT
Times cited: 63
A phase Ib study of BGJ398, a pan-FGFR kinase inhibitor in combination with imatinib in patients with advanced gastrointestinal stromal tumor. Investigational new drugs. 2018 Academic Article GET IT
Times cited: 26
PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence. Oncogene. 2018 Academic Article GET IT
Times cited: 25
Enoxaparin vs Aspirin in Patients With Cancer and Ischemic Stroke: The TEACH Pilot Randomized Clinical Trial. JAMA neurology. 2018 Academic Article GET IT
Times cited: 41
ATRX is a regulator of therapy induced senescence in human cells. Nature communications. 2017 Academic Article GET IT
Times cited: 42
Sarcomas With CIC-rearrangements Are a Distinct Pathologic Entity With Aggressive Outcome: A Clinicopathologic and Molecular Study of 115 Cases. The American journal of surgical pathology. 2017 Academic Article GET IT
Times cited: 236
Treatment Recommendations for Retroperitoneal Liposarcoma. International journal of radiation oncology, biology, physics. 2017 Comment GET IT
Times cited: 1
Pulmonary metastasectomy with therapeutic intent for soft-tissue sarcoma. The Journal of thoracic and cardiovascular surgery. 2017 Academic Article GET IT
Times cited: 80
BCOR upregulation in a poorly differentiated synovial sarcoma with SS18L1-SSX1 fusion-A pathologic and molecular pitfall. 2017 GET IT
Times cited: 28
Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma. Cancer discovery. 2016 Academic Article GET IT
Times cited: 53
Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma. Cancer research. 2016 Academic Article GET IT
Times cited: 23
Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial. JAMA oncology. 2016 Academic Article GET IT
Times cited: 201
Empirical insights into the stochasticity of small RNA sequencing. Scientific reports. 2016 Academic Article GET IT
Times cited: 5
Histology-based Classification Predicts Pattern of Recurrence and Improves Risk Stratification in Primary Retroperitoneal Sarcoma. Annals of surgery. 2016 Academic Article GET IT
Times cited: 209
Optimal Percent Myxoid Component to Predict Outcome in High-Grade Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma. Annals of surgical oncology. 2016 Academic Article GET IT
Times cited: 31
Targeted exome sequencing profiles genetic alterations in leiomyosarcoma. Genes, chromosomes & cancer. 2015 Academic Article GET IT
Times cited: 30
A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas. The oncologist. 2015 Academic Article GET IT
Times cited: 23
Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid-type fibromatosis by whole-exome sequencing and genomic analysis. Genes, chromosomes & cancer. 2015 Academic Article GET IT
Times cited: 109
Comparison of Perioperative Radiation Therapy and Surgery Versus Surgery Alone in 204 Patients With Primary Retroperitoneal Sarcoma: A Retrospective 2-Institution Study. Annals of surgery. 2015 Academic Article GET IT
Times cited: 60
Posterior Reversible Encephalopathy Syndrome in Patients With Cancer. The oncologist. 2015 Academic Article GET IT
Times cited: 67
MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. Oncotarget. 2015 Academic Article GET IT
Times cited: 86
Diagnostic yield of echocardiography in cancer patients with ischemic stroke. Journal of neuro-oncology. 2015 Academic Article GET IT
Times cited: 21
Soft tissue sarcoma of the head & neck: nomogram validation and analysis of staging systems. Journal of surgical oncology. 2015 Academic Article GET IT
Times cited: 16
Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging. Science translational medicine. 2015 Academic Article GET IT
Times cited: 204
Application of molecular biology to individualize therapy for patients with liposarcoma. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting. 2015 Review GET IT
Times cited: 19
Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing. Genes, chromosomes & cancer. 2014 Academic Article GET IT
Times cited: 24
PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors. Nature genetics. 2014 Academic Article GET IT
Times cited: 386
Comparison of local recurrence with conventional and intensity-modulated radiation therapy for primary soft-tissue sarcomas of the extremity. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2014 Academic Article GET IT
Times cited: 96
Lessons learned from the study of 10,000 patients with soft tissue sarcoma. Annals of surgery. 2014 Academic Article GET IT
Times cited: 270
Cryptogenic subtype predicts reduced survival among cancer patients with ischemic stroke. Stroke. 2014 Academic Article GET IT
Times cited: 67
Recurrent thromboembolic events after ischemic stroke in patients with cancer. Neurology. 2014 Academic Article GET IT
Times cited: 111
A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations. Nature genetics. 2014 Academic Article GET IT
Times cited: 125
Consistent SMARCB1 homozygous deletions in epithelioid sarcoma and in a subset of myoepithelial carcinomas can be reliably detected by FISH in archival material. Genes, chromosomes & cancer. 2014 Academic Article GET IT
Times cited: 106
Infiltration of the optic chiasm, nerve, and disc by gliomatosis cerebri. 2014 GET IT
Times cited: 5
Extraskeletal myxoid chondrosarcoma with non-EWSR1-NR4A3 variant fusions correlate with rhabdoid phenotype and high-grade morphology. Human pathology. 2014 Academic Article GET IT
Times cited: 71
High-risk features in radiation-associated breast angiosarcomas. British journal of cancer. 2013 Academic Article GET IT
Times cited: 48
Small-Molecule targeting of translation initiation for cancer therapy. Oncotarget. 2013 Academic Article GET IT
Times cited: 24
Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets. Science signaling. 2013 Academic Article GET IT
Times cited: 71
A prognostic nomogram for prediction of recurrence in desmoid fibromatosis. Annals of surgery. 2013 Academic Article GET IT
Times cited: 175
Toward better soft tissue sarcoma staging: building on american joint committee on cancer staging systems versions 6 and 7. Annals of surgical oncology. 2013 Academic Article GET IT
Times cited: 49
Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2013 Academic Article GET IT
Times cited: 330
An Empirical Evaluation of Normalization Methods for MicroRNA Arrays in a Liposarcoma Study. Cancer informatics. 2013 Academic Article GET IT
Times cited: 96
Adult rhabdomyosarcoma survival improved with treatment on multimodality protocols. International journal of radiation oncology, biology, physics. 2013 Academic Article GET IT
Times cited: 56
Predictors of survival and recurrence in primary leiomyosarcoma. Annals of surgical oncology. 2013 Academic Article GET IT
Times cited: 100
Blood neutrophil-to-lymphocyte ratio is prognostic in gastrointestinal stromal tumor. Annals of surgical oncology. 2012 Academic Article GET IT
Times cited: 69
SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors. BMC cancer. 2012 Academic Article GET IT
Times cited: 49
Prognostic factors and survival in pediatric and adolescent liposarcoma. Sarcoma. 2012 Academic Article GET IT
Times cited: 17
Oncologic outcomes of sporadic, neurofibromatosis-associated, and radiation-induced malignant peripheral nerve sheath tumors. Annals of surgical oncology. 2012 Academic Article GET IT
Times cited: 97
Pediatric and adolescent synovial sarcoma: multivariate analysis of prognostic factors and survival outcomes. Annals of surgical oncology. 2012 Academic Article GET IT
Times cited: 30
Patterns of deregulation of insulin growth factor signalling pathway in paediatric and adult gastrointestinal stromal tumours. European journal of cancer (Oxford, England : 1990). 2012 Academic Article GET IT
Times cited: 7
Subdural hematoma in patients with cancer. Neurosurgery. 2012 Academic Article GET IT
Times cited: 25
The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. Genes, chromosomes & cancer. 2012 Academic Article GET IT
Times cited: 84
The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial. Clinical cancer research : an official journal of the American Association for Cancer Research. 2012 Academic Article GET IT
Times cited: 78
A postoperative nomogram for local recurrence risk in extremity soft tissue sarcomas after limb-sparing surgery without adjuvant radiation. Annals of surgery. 2012 Academic Article GET IT
Times cited: 114
Copy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability. Clinical cancer research : an official journal of the American Association for Cancer Research. 2012 Academic Article GET IT
Times cited: 57
Restoration of C/EBPα in dedifferentiated liposarcoma induces G2/M cell cycle arrest and apoptosis. Genes, chromosomes & cancer. 2011 Academic Article GET IT
Times cited: 22
CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers. Genes, chromosomes & cancer. 2011 Academic Article GET IT
Times cited: 18
High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas. Genes, chromosomes & cancer. 2011 Academic Article GET IT
Times cited: 279
Advanced well-differentiated/dedifferentiated liposarcomas: role of chemotherapy and survival. Annals of oncology : official journal of the European Society for Medical Oncology. 2011 Academic Article GET IT
Times cited: 104
Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data. Genes, chromosomes & cancer. 2011 Academic Article GET IT
Times cited: 247
Rhomboencephalitis due to cocaine-induced bony erosion of skull base. 2011 GET IT
Times cited: 4
Advances in sarcoma genomics and new therapeutic targets. Nature reviews. Cancer. 2011 Review GET IT
Times cited: 311
Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma. Current opinion in oncology. 2011 Review GET IT
Times cited: 191
The enigma of myxofibrosarcoma of the extremity. Cancer. 2011 Academic Article GET IT
Times cited: 50
Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma. Cancer research. 2011 Academic Article GET IT
Times cited: 98
A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites. Genes, chromosomes & cancer. 2011 Academic Article GET IT
Times cited: 369
Soft tissue sarcoma diagnosed subsequent to lymphoma is associated with prior radiotherapy and decreased survival. Cancer. 2011 Academic Article GET IT
Times cited: 3
Activity of Sorafenib against desmoid tumor/deep fibromatosis. Clinical cancer research : an official journal of the American Association for Cancer Research. 2011 Academic Article GET IT
Times cited: 198
Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS. NMR in biomedicine. 2011 Academic Article GET IT
Times cited: 4
mRNA and protein levels of FUS, EWSR1, and TAF15 are upregulated in liposarcoma. Genes, chromosomes & cancer. 2011 Academic Article GET IT
Times cited: 18
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Cancer research. 2011 Academic Article GET IT
Times cited: 86
Local control comparison of adjuvant brachytherapy to intensity-modulated radiotherapy in primary high-grade sarcoma of the extremity. Cancer. 2011 Academic Article GET IT
Times cited: 56
Laparoscopic versus open gastric resections for primary gastrointestinal stromal tumors (GISTs): a size-matched comparison. Annals of surgical oncology. 2011 Academic Article GET IT
Times cited: 134
Consistent MYC and FLT4 gene amplification in radiation-induced angiosarcoma but not in other radiation-associated atypical vascular lesions. Genes, chromosomes & cancer. 2011 Academic Article GET IT
Times cited: 245
Dermatofibrosarcoma protuberans (DFSP): predictors of recurrence and the use of systemic therapy. Annals of surgical oncology. 2010 Academic Article GET IT
Times cited: 72
ZIC1 overexpression is oncogenic in liposarcoma. Cancer research. 2010 Academic Article GET IT
Times cited: 38
IGF2 over-expression in solitary fibrous tumours is independent of anatomical location and is related to loss of imprinting. The Journal of pathology. 2010 Academic Article GET IT
Times cited: 73
A differentiation-based phylogeny of cancer subtypes. PLoS computational biology. 2010 Academic Article GET IT
Times cited: 32
Clinical outcomes of systemic therapy for patients with deep fibromatosis (desmoid tumor). Cancer. 2010 Academic Article GET IT
Times cited: 148
Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas?. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2010 Academic Article GET IT
Times cited: 200
Fat-free MRI based on magnetization exchange. Magnetic resonance in medicine. 2010 Academic Article GET IT
Times cited: 12
Predicting outcome by growth rate of locally recurrent retroperitoneal liposarcoma: the one centimeter per month rule. Annals of surgery. 2009 Academic Article GET IT
Times cited: 96
Mechanisms of sunitinib resistance in gastrointestinal stromal tumors harboring KITAY502-3ins mutation: an in vitro mutagenesis screen for drug resistance. Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Academic Article GET IT
Times cited: 73
Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis. The Lancet. Oncology. 2009 Academic Article GET IT
Times cited: 396
KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors. Cancer research. 2009 Academic Article GET IT
Times cited: 218
Influence of compartmental involvement on the patterns of morbidity in soft tissue sarcoma of the thigh. Cancer. 2009 Academic Article GET IT
Times cited: 42
A synovial sarcoma-specific preoperative nomogram supports a survival benefit to ifosfamide-based chemotherapy and improves risk stratification for patients. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008 Academic Article GET IT
Times cited: 141
Extraskeletal myxoid chondrosarcoma: a retrospective review from 2 referral centers emphasizing long-term outcomes with surgery and chemotherapy. Cancer. 2008 Academic Article GET IT
Times cited: 114
Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors. Genes, chromosomes & cancer. 2008 Academic Article GET IT
Times cited: 300
Why do patients with low-grade soft tissue sarcoma die?. Annals of surgical oncology. 2008 Academic Article GET IT
Times cited: 53
Functional copy-number alterations in cancer. PloS one. 2008 Academic Article GET IT
Times cited: 133
Impact of intensity-modulated radiation therapy on local control in primary soft-tissue sarcoma of the extremity. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 114
Long-term outcomes in extremity soft tissue sarcoma after a pathologically negative re-resection and without radiotherapy. Cancer. 2008 Academic Article GET IT
Times cited: 29
Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells. Molecular cancer therapeutics. 2008 Academic Article GET IT
Times cited: 66
A tribute to Murray F. Brennan, MD. Journal of surgical oncology. 2008 Academic Article GET IT
Diagnosis and management of lipomatous tumors. Journal of surgical oncology. 2008 Review GET IT
Times cited: 164
A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. The American journal of pathology. 2008 Academic Article GET IT
Times cited: 60
Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST). Cancer. 2008 Academic Article GET IT
Times cited: 413
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway. The Journal of clinical investigation. 2007 Academic Article GET IT
Times cited: 158
Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft-tissue sarcoma of the extremity : a retrospective analysis. Cancer. 2007 Academic Article GET IT
Times cited: 43
Sorafenib inhibits the imatinib-resistant KITT670I gatekeeper mutation in gastrointestinal stromal tumor. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007 Academic Article GET IT
Times cited: 124
Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma. Cancer research. 2007 Academic Article GET IT
Times cited: 212
Chemotherapy is associated with improved survival in adult patients with primary extremity synovial sarcoma. Annals of surgery. 2007 Academic Article GET IT
Times cited: 171
Intensity modulated radiation therapy for primary soft tissue sarcoma of the extremity: preliminary results. International journal of radiation oncology, biology, physics. 2007 Academic Article GET IT
Times cited: 53
Results of tyrosine kinase inhibitor therapy followed by surgical resection for metastatic gastrointestinal stromal tumor. Annals of surgery. 2007 Academic Article GET IT
Times cited: 268
Skeletal metastases in myxoid liposarcoma: an unusual pattern of distant spread. Annals of surgical oncology. 2007 Academic Article GET IT
Times cited: 87
Pathologic and molecular heterogeneity in imatinib-stable or imatinib-responsive gastrointestinal stromal tumors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007 Academic Article GET IT
Times cited: 104
Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1. Oncogene. 2006 Academic Article GET IT
Times cited: 145
Outcome of metastatic GIST in the era before tyrosine kinase inhibitors. Annals of surgical oncology. 2006 Academic Article GET IT
Times cited: 112
Angiogenic profile of soft tissue sarcomas based on analysis of circulating factors and microarray gene expression. The Journal of surgical research. 2006 Academic Article GET IT
Times cited: 58
Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk. Annals of surgery. 2006 Academic Article GET IT
Times cited: 266
Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells. Cancer research. 2006 Academic Article GET IT
Times cited: 74
High-resolution MAS NMR spectroscopy detection of the spin magnetization exchange by cross-relaxation and chemical exchange in intact cell lines and human tissue specimens. Magnetic resonance in medicine. 2006 Academic Article GET IT
Times cited: 42
Effectiveness of palliative procedures for intra-abdominal sarcomas. Annals of surgical oncology. 2005 Academic Article GET IT
Times cited: 31
Influence of site on the therapeutic ratio of adjuvant radiotherapy in soft-tissue sarcoma of the extremity. International journal of radiation oncology, biology, physics. 2005 Academic Article GET IT
Times cited: 47
Distant metastasis in retroperitoneal dedifferentiated liposarcoma is rare and rapidly fatal: a clinicopathological study with emphasis on the low-grade myxofibrosarcoma-like pattern as an early sign of dedifferentiation. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2005 Academic Article GET IT
Times cited: 58
Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. Clinical cancer research : an official journal of the American Association for Cancer Research. 2005 Academic Article GET IT
Times cited: 699
Prognostic factors for survival in patients with locally recurrent extremity soft tissue sarcomas. Annals of surgical oncology. 2005 Academic Article GET IT
Times cited: 60
Multiple primary soft tissue sarcomas. Cancer. 2004 Academic Article GET IT
Times cited: 32
Validation of the postoperative nomogram for 12-year sarcoma-specific mortality. Cancer. 2004 Academic Article GET IT
Times cited: 120
Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma. Annals of oncology : official journal of the European Society for Medical Oncology. 2004 Academic Article GET IT
Times cited: 173
Water suppression without signal loss in HR-MAS 1H NMR of cells and tissues. Journal of magnetic resonance (San Diego, Calif. : 1997). 2004 Academic Article GET IT
Times cited: 27
Liposarcoma subtypes: identification with computed tomography and ultrasound-guided percutaneous needle biopsy. European radiology. 2004 Academic Article GET IT
Times cited: 12
The impact of chemotherapy on the survival of patients with high-grade primary extremity liposarcoma. Annals of surgery. 2004 Academic Article GET IT
Times cited: 137
Circulating angiogenic factor levels correlate with extent of disease and risk of recurrence in patients with soft tissue sarcoma. Annals of oncology : official journal of the European Society for Medical Oncology. 2004 Academic Article GET IT
Times cited: 78
Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs). Oncogene. 2004 Academic Article GET IT
Times cited: 285
Reconstruction after soft tissue sarcoma resection in the setting of brachytherapy: a 10-year experience. Annals of plastic surgery. 2004 Academic Article GET IT
Times cited: 14
Evaluation of a clinically applicable post-surgical classification system for primary retroperitoneal soft-tissue sarcoma. Annals of surgical oncology. 2004 Academic Article GET IT
Times cited: 76
Synovial sarcoma: the importance of size and location for survival. Clinical orthopaedics and related research. 2004 Academic Article GET IT
Times cited: 106
Atypical lipomatous tumor/well-differentiated liposarcoma of the extremity and trunk wall: importance of histological subtype with treatment recommendations. Annals of surgical oncology. 2004 Academic Article GET IT
Times cited: 106
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2003 Academic Article GET IT
Times cited: 1982
Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Annals of surgery. 2003 Academic Article GET IT
Times cited: 469
Isotropic susceptibility shift under MAS: the origin of the split water resonances in 1H MAS NMR spectra of cell suspensions. Magnetic resonance in medicine. 2003 Academic Article GET IT
Times cited: 28
Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2003 Academic Article GET IT
Times cited: 257
Soft tissue sarcomas of adults: state of the translational science. Clinical cancer research : an official journal of the American Association for Cancer Research. 2003 Review GET IT
Times cited: 264
PDGFRA activating mutations in gastrointestinal stromal tumors. Science (New York, N.Y.). 2003 Academic Article GET IT
Times cited: 2030
Biochemical correlates of thiazolidinedione-induced adipocyte differentiation by high-resolution magic angle spinning NMR spectroscopy. Magnetic resonance in medicine. 2002 Academic Article GET IT
Times cited: 33
PPARgamma ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis. The Journal of clinical investigation. 2002 Academic Article GET IT
Times cited: 351
Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2002 Academic Article GET IT
Times cited: 405
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. The New England journal of medicine. 2002 Academic Article GET IT
Times cited: 3772
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer research. 2001 Academic Article GET IT
Times cited: 892
Biochemical analysis using high-resolution magic angle spinning NMR spectroscopy distinguishes lipoma-like well-differentiated liposarcoma from normal fat. Journal of the American Chemical Society. 2001 Academic Article GET IT
Times cited: 55
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications. Oncogene. 2001 Academic Article GET IT
Times cited: 623
Response to chemotherapy and predictors of survival in adult rhabdomyosarcoma. Annals of surgery. 2001 Academic Article GET IT
Times cited: 127
MR imaging-guided focused ultrasound surgery of fibroadenomas in the breast: a feasibility study. Radiology. 2001 Academic Article GET IT
Times cited: 539
Management of soft-tissue sarcomas: an overview and update. The Lancet. Oncology. 2000 Review GET IT
Times cited: 151
KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors. The American journal of pathology. 2000 Academic Article GET IT
Times cited: 589
Different patterns of angiogenesis in sarcomas and carcinomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 1999 Academic Article GET IT
Times cited: 60
Uptake of radiolabeled somatostatin analog is detectable in patients with metastatic foci of sarcoma. 1999 GET IT
Times cited: 12
Long-term outcomes after function-sparing surgery without radiotherapy for soft tissue sarcoma of the extremities and trunk. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1999 Academic Article GET IT
Times cited: 160
Adults with Ewing's sarcoma/primitive neuroectodermal tumor: adverse effect of older age and primary extraosseous disease on outcome. Annals of surgery. 1999 Academic Article GET IT
Times cited: 111
Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma. 1999 GET IT
Times cited: 466
Classification of human liposarcoma and lipoma using ex vivo proton NMR spectroscopy. Magnetic resonance in medicine. 1999 Academic Article GET IT
Times cited: 94
New diagnostic modalities in soft tissue sarcoma. Seminars in surgical oncology. 1999 Review GET IT
Times cited: 24
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proceedings of the National Academy of Sciences of the United States of America. 1998 Academic Article GET IT
Times cited: 506
Differentiation and reversal of malignant changes in colon cancer through PPARgamma. Nature medicine. 1998 Academic Article GET IT
Times cited: 930
Diagnosis in oncology. Askin tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1998 Academic Article GET IT
Times cited: 5
Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis. 1998 GET IT
Times cited: 80
Gradient, high-resolution, magic angle spinning 1H nuclear magnetic resonance spectroscopy of intact cells. Magnetic resonance in medicine. 1998 Academic Article GET IT
Times cited: 131
Terminal differentiation of human breast cancer through PPAR gamma. Molecular cell. 1998 Academic Article GET IT
Times cited: 781
Single-stage, multimodality treatment of soft-tissue sarcoma of the extremity. 1997 GET IT
Times cited: 18
Gradient, high-resolution, magic-angle spinning nuclear magnetic resonance spectroscopy of human adipocyte tissue. Magnetic resonance in medicine. 1997 Academic Article GET IT
Times cited: 125
Angiosarcoma. 1997 GET IT
Times cited: 4
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. Proceedings of the National Academy of Sciences of the United States of America. 1997 Academic Article GET IT
Times cited: 619
A phase I study of vaccination with autologous, irradiated melanoma cells engineered to secrete human granulocyte-macrophage colony stimulating factor. Human gene therapy. 1997 Academic Article GET IT
Times cited: 57
Correlation of lipid content and composition with liposarcoma histology and grade. Annals of surgical oncology. 1997 Academic Article GET IT
Times cited: 21
Surgical management of soft-tissue sarcoma. Advances in surgery. 1997 Review GET IT
Times cited: 19
1H-NMR detectable fatty acyl chain unsaturation in excised leiomyosarcoma correlate with grade and mitotic activity. The Journal of clinical investigation. 1996 Academic Article GET IT
Times cited: 32
Synovial sarcoma: prognostic significance of tumor size, margin of resection, and mitotic activity for survival. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1996 Academic Article GET IT
Times cited: 167
Pyruvate utilization, phosphocholine and adenosine triphosphate (ATP) are markers of human breast tumor progression: a 31P- and 13C-nuclear magnetic resonance (NMR) spectroscopy study. Cancer research. 1995 Academic Article GET IT
Times cited: 66
Prognostic factors predictive of survival for truncal and retroperitoneal soft-tissue sarcoma. Annals of surgery. 1995 Academic Article GET IT
Times cited: 261
Translocation t(8;13)(p11;q11-12) in stem cell leukemia/lymphoma of T-cell and myeloid lineages. Genes, chromosomes & cancer. 1995 Academic Article GET IT
Times cited: 25
Ex vivo two-dimensional proton nuclear magnetic resonance spectroscopy of smooth muscle tumors: advantages of total correlated spectroscopy over homonuclear J-correlated spectroscopy. Cancer research. 1994 Academic Article GET IT
Times cited: 16
Prognostic factors predictive of survival and local recurrence for extremity soft tissue sarcoma. Annals of surgery. 1994 Academic Article GET IT
Times cited: 196
13C- and 31P-NMR studies of human colon cancer in-vitro and in-vivo. Surgical oncology. 1993 Academic Article GET IT
Times cited: 14
Long-term salvageability for patients with locally recurrent soft-tissue sarcomas. Archives of surgery (Chicago, Ill. : 1960). 1992 Academic Article GET IT
Times cited: 46
Angiogenesis determines blood flow, metabolism, growth rate, and ATPase kinetics of tumors growing in an irradiated bed: 31P and 2H nuclear magnetic resonance studies. Cancer research. 1991 Academic Article GET IT
Times cited: 41
Lack of efficacy of water-suppressed proton nuclear magnetic resonance spectroscopy of plasma for the detection of malignant tumors. The New England journal of medicine. 1990 Academic Article GET IT
Times cited: 32
Chloride flux from blood to CSF: inhibition by furosemide and bumetanide. Journal of applied physiology (Bethesda, Md. : 1985). 1987 Academic Article GET IT
Times cited: 25

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Background

education and training

M.D., Harvard Medical School 1982
B.S., Massachusetts Institute of Technology 1979

Contact

full name

Samuel Singer

VIVO Weill Cornell Medical College

Samuel Singer Professor of Surgery

Publications

selected publications

Background

education and training

Contact

full name