GAMMA GLOBULIN: UNMASKING OF HIDDEN ANTIGENIC SITES ON LIGHT CHAINS. Academic Article uri icon

Overview

abstract

  • Normal light (L) chains cleaved from normal pooled human gamma globulin contain immunologic determinants not overtly present in the native unreduced molecule. These hidden determinants are shared with Bence Jones proteins. Similarly, one of two Bence Jones proteins contained immunologic determinants which were not overtly present on the autologous serum myeloma protein.

publication date

  • July 10, 1964

Research

keywords

  • Antigens
  • Bence Jones Protein
  • Immunodiffusion
  • Multiple Myeloma
  • Peptides
  • Precipitin Tests
  • Research
  • gamma-Globulins

Identity

Scopus Document Identifier

  • 37049248566

Digital Object Identifier (DOI)

  • 10.1126/science.145.3628.167

PubMed ID

  • 14171555

Additional Document Info

volume

  • 145

issue

  • 3628