Brain polysomes: response to environmental stimulation. Academic Article uri icon

Overview

abstract

  • Polysomes have been isolated from rat brain and characterized by their appearance in the electron microscope and by their sedimentation in sucrose density gradients. Rats were isolated for 3 days in the dark and were then returned to the light for 15 minutes. The polysomes in brain, but not in liver, decreased in rats deprived of light and increased in those stimulated with light. These findings together with an increased capacity for protein synthesis in the brain in vitro and in vivo suggest that an increase in the activity of messenger RNA in the brain may result from environmental changes.

publication date

  • August 18, 1967

Identity

Scopus Document Identifier

  • 6844246755

Digital Object Identifier (DOI)

  • 10.1126/science.157.3790.836

PubMed ID

  • 17842798

Additional Document Info

volume

  • 157

issue

  • 3790