Genetics of cardiac repolarization. uri icon

Overview

abstract

  • Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide association studies (GWAS) of variation in the QT interval in population-based cohorts now report association with variants in a subset of ion channel genes and other new associations.

publication date

  • April 1, 2009

Research

keywords

  • Arrhythmias, Cardiac
  • Heart
  • Ion Channels
  • Long QT Syndrome

Identity

Scopus Document Identifier

  • 84984760178

Digital Object Identifier (DOI)

  • 10.1038/ng0409-388

PubMed ID

  • 19338079

Additional Document Info

volume

  • 41

issue

  • 4