Fishing for a WNT-PGE2 link: beta-catenin is caught in the stem cell net-work. Academic Article uri icon

Overview

abstract

  • WNT and PGE2 signaling pathways are each associated with stem cell activity in the hematopoietic system. In a recent issue of Cell, Goessling et al. (2009) use the zebrafish model to reveal a conserved PKA-dependent mechanism that connects the two pathways via beta-catenin, enhancing stem cell proliferation and tissue regeneration.

publication date

  • April 3, 2009

Research

keywords

  • Dinoprostone
  • Stem Cells
  • Wnt Proteins
  • Zebrafish
  • Zebrafish Proteins
  • beta Catenin

Identity

Scopus Document Identifier

  • 62949109517

Digital Object Identifier (DOI)

  • 10.1016/j.stem.2009.03.006

PubMed ID

  • 19341616

Additional Document Info

volume

  • 4

issue

  • 4