Evans, Todd R.

Publications

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selected publications

A Targetable Pathway to Eliminate TRA-1-60+/TRA-1-81+ Chemoresistant Cancer Cells. Journal of molecular cell biology. 2023 Academic Article GET IT
An evolutionarily conserved pacemaker role for HCN ion channels in smooth muscle. The Journal of physiology. 2023 Academic Article GET IT
A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection. Nature cell biology. 2023 Academic Article GET IT
Times cited: 413
Dual role of lipids for genome stability and pluripotency facilitates full potency of mouse embryonic stem cells. Protein & cell. 2023 Academic Article GET IT
Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children. Science (New York, N.Y.). 2023 Academic Article GET IT
Times cited: 13
Development of a New Methodology for Dearomative Borylation of Coumarins and Chromenes and Its Applications to Synthesize Boron-Containing Retinoids. Molecules (Basel, Switzerland). 2023 Academic Article GET IT
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants. Cell stem cell. 2022 Academic Article GET IT
Times cited: 111
Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective. Molecules (Basel, Switzerland). 2022 Review GET IT
Times cited: 27
A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells. iScience. 2022 Academic Article GET IT
Times cited: 4613
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells. Circulation research. 2022 Academic Article GET IT
Times cited: 23
Comments on 'An airway organoid-based screen identifies a role for the HIF1α‒glycolysis axis in SARS-CoV-2 infection'. Journal of molecular cell biology. 2022 Comment GET IT
Times cited: 1
Synthesis of a boron-containing amidoxime reagent and its application to synthesize functionalized oxadiazole and quinazolinone derivatives. Tetrahedron letters. 2022 Academic Article GET IT
Times cited: 5
Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation. Cell reports. 2021 Academic Article GET IT
Times cited: 4
An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection. Cell reports. 2021 Academic Article GET IT
Times cited: 26
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2. Stem cell reports. 2021 Article GET IT
Times cited: 3
Constitutively Activating GNAS Somatic Mutation in Right Ventricular Outflow Tract Tachycardia. 2021 GET IT
Times cited: 2
Sirt1 promotes tissue regeneration in zebrafish through regulating the mitochondrial unfolded protein response. iScience. 2021 Academic Article GET IT
Times cited: 8
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2. Stem cell reports. 2021 Academic Article GET IT
Times cited: 26
SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence. Research square. 2021 Article GET IT
SARS-CoV-2 infection induces beta cell transdifferentiation. Cell metabolism. 2021 Academic Article GET IT
Times cited: 90
The small molecule DIPQUO promotes osteogenic differentiation via inhibition of glycogen synthase kinase 3-beta signaling. The Journal of biological chemistry. 2021 Academic Article GET IT
Times cited: 3
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts. Circulation research. 2021 Academic Article GET IT
Times cited: 25
QSER1 protects DNA methylation valleys from de novo methylation. Science (New York, N.Y.). 2021 Academic Article GET IT
Times cited: 39
Prospective Isolation of ISL1⁺ Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy. Stem cell reports. 2021 Article GET IT
Tet Proteins Regulate Neutrophil Granulation in Zebrafish through Demethylation of socs3b mRNA. Cell reports. 2021 Academic Article GET IT
Times cited: 8
SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2. Research square. 2020 Article GET IT
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2020 Academic Article GET IT
Times cited: 274
Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes. EBioMedicine. 2020 Academic Article GET IT
Times cited: 14
Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2. Research square. 2020 Article GET IT
Modeling endodermal organ development and diseases using human pluripotent stem cell-derived organoids. Journal of molecular cell biology. 2020 Review GET IT
Times cited: 3
Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis. Biology open. 2020 Academic Article GET IT
Times cited: 53
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids. Cell stem cell. 2020 Academic Article GET IT
Times cited: 420
Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids. bioRxiv : the preprint server for biology. 2020 Article GET IT
A human embryonic stem cell reporter line for monitoring chemical-induced cardiotoxicity. Cardiovascular research. 2020 Academic Article GET IT
Times cited: 9
Sphingosine kinases protect murine embryonic stem cells from sphingosine-induced cell cycle arrest. Stem cells (Dayton, Ohio). 2020 Academic Article GET IT
Times cited: 1
Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells. Nature communications. 2019 Academic Article GET IT
Times cited: 20
Epigenetic Regulation of Cardiac Development and Disease through DNA Methylation. Journal of life sciences (Westlake Village, Calif.). 2019 Academic Article GET IT
Times cited: 438
TMEM88 Inhibits Wnt Signaling by Promoting Wnt Signalosome Localization to Multivesicular Bodies. iScience. 2019 Academic Article GET IT
Times cited: 12
Inducible Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome. Circulation. 2019 Academic Article GET IT
Times cited: 38
Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation. Nature genetics. 2019 Academic Article GET IT
Times cited: 58
Activation-Induced Cytidine Deaminase Regulates Fibroblast Growth Factor/Extracellular Signal-Regulated Kinases Signaling to Achieve the Naïve Pluripotent State During Reprogramming. Stem cells (Dayton, Ohio). 2019 Academic Article GET IT
Times cited: 2
Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β. Cell chemical biology. 2019 Academic Article GET IT
Times cited: 13
Concise Review: Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering. Stem cells translational medicine. 2019 Review GET IT
Times cited: 24
BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress. Cancer discovery. 2019 Academic Article GET IT
Times cited: 26
Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors. Neuron. 2019 Academic Article GET IT
Times cited: 43
TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis. Cell reports. 2019 Academic Article GET IT
Times cited: 12
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival. Nature communications. 2018 Academic Article GET IT
Times cited: 20
Discovery of a drug candidate for GLIS3-associated diabetes. Nature communications. 2018 Academic Article GET IT
Times cited: 39
Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nature medicine. 2018 Article GET IT
Times cited: 5
Prospective Isolation of ISL1⁺ Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy. Stem cell reports. 2018 Academic Article GET IT
Times cited: 17
Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor. ACS chemical biology. 2018 Academic Article GET IT
Times cited: 19
Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis. Developmental biology. 2018 Academic Article GET IT
Times cited: 29
The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. eLife. 2017 Academic Article GET IT
Times cited: 11
ROCKII inhibition promotes the maturation of human pancreatic beta-like cells. Nature communications. 2017 Academic Article GET IT
Times cited: 60
High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain. Cell stem cell. 2017 Academic Article GET IT
Times cited: 162
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nature medicine. 2017 Academic Article GET IT
Times cited: 226
Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E. Cell reports. 2017 Academic Article GET IT
Times cited: 25
Congenital heart disease in a dish: progress toward understanding patient-specific mutations. Journal of thoracic disease. 2017 Editorial Article GET IT
Times cited: 79
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell stem cell. 2017 Academic Article GET IT
Times cited: 104
Efficient Generation of Cardiac Purkinje-like Cells from Embryonic Stem Cells by Activating cAMP Signaling. Current protocols in stem cell biology. 2017 Academic Article GET IT
Times cited: 4
An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery. Cell stem cell. 2016 Academic Article GET IT
Times cited: 80
Discovery of a Small-Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation. Cell reports. 2016 Academic Article GET IT
Times cited: 16
Modeling Cystic Fibrosis Using Pluripotent Stem Cell-Derived Human Pancreatic Ductal Epithelial Cells. Stem cells translational medicine. 2016 Academic Article GET IT
Times cited: 37
Epigenetic regulation of hematopoietic stem cell development. Methods in cell biology. 2016 Academic Article GET IT
Times cited: 4
Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes. Proceedings of the National Academy of Sciences of the United States of America. 2015 Academic Article GET IT
Times cited: 26
Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence. Cell reports. 2015 Academic Article GET IT
Times cited: 64
Maternal or zygotic sphingosine kinase is required to regulate zebrafish cardiogenesis. Developmental dynamics : an official publication of the American Association of Anatomists. 2015 Academic Article GET IT
Times cited: 10
Orchestrating liver development. Development (Cambridge, England). 2015 Review GET IT
Times cited: 208
Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling. Stem cell reports. 2015 Academic Article GET IT
Times cited: 27
BMP signaling balances murine myeloid potential through SMAD-independent p38MAPK and NOTCH pathways. Blood. 2014 Academic Article GET IT
Times cited: 11
Silencing of UCHL1 by CpG promoter hyper-methylation is associated with metastatic gastroenteropancreatic well-differentiated neuroendocrine (carcinoid) tumors. Annals of surgical oncology. 2014 Academic Article GET IT
Times cited: 15
Redox modification of nuclear actin by MICAL-2 regulates SRF signaling. Cell. 2014 Academic Article GET IT
Times cited: 124
Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1. Blood. 2014 Academic Article GET IT
Times cited: 25
Biological function of activation-induced cytidine deaminase (AID). Biomedical journal. 2014 Review GET IT
Times cited: 36
Sphingosine 1-phosphate signalling. Development (Cambridge, England). 2014 Review GET IT
Times cited: 190
Retinoic acid signaling pathways in development and diseases. Bioorganic & medicinal chemistry. 2013 Review GET IT
Times cited: 179
Use of zebrafish in chemical biology and drug discovery. Future medicinal chemistry. 2013 Review GET IT
Times cited: 21
Tmem88a mediates GATA-dependent specification of cardiomyocyte progenitors by restricting WNT signaling. Development (Cambridge, England). 2013 Academic Article GET IT
Times cited: 17
Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis. Developmental biology. 2013 Academic Article GET IT
Times cited: 23
AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes. Nature. 2013 Academic Article GET IT
Times cited: 76
An injury-responsive gata4 program shapes the zebrafish cardiac ventricle. Current biology : CB. 2013 Academic Article GET IT
Times cited: 81
KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell stem cell. 2013 Academic Article GET IT
Times cited: 44
Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 50
A zebrafish model for uremic toxicity: role of the complement pathway. Blood purification. 2013 Academic Article GET IT
Times cited: 8
Boron chemicals in diagnosis and therapeutics. Future medicinal chemistry. 2013 Review GET IT
Times cited: 183
GATA factors efficiently direct cardiac fate from embryonic stem cells. Development (Cambridge, England). 2013 Academic Article GET IT
Times cited: 36
The Congenital Heart Disease Genetic Network Study: rationale, design, and early results. Circulation research. 2013 Academic Article GET IT
Times cited: 111
Sphingosine 1-phosphate receptor signaling regulates proper embryonic vascular patterning. The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 60
Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis. The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 63
Regulation of a vascular plexus by gata4 is mediated in zebrafish through the chemokine sdf1a. PloS one. 2012 Academic Article GET IT
Times cited: 6
Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development. Developmental cell. 2012 Academic Article GET IT
Times cited: 231
Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs. Tetrahedron letters. 2012 Academic Article GET IT
Times cited: 22
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental cell. 2012 Academic Article GET IT
Times cited: 73
Design and synthesis of boron containing potential pan-RAR inverse agonists. Tetrahedron letters. 2012 Academic Article GET IT
Times cited: 38
Novel retinoic acid receptor alpha agonists for treatment of kidney disease. PloS one. 2011 Academic Article GET IT
Times cited: 39
Design and Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazole Containing Retinoids from a Retinoic Acid Receptor Agonist. Tetrahedron letters. 2011 Academic Article GET IT
Times cited: 6
Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment. Blood. 2011 Academic Article GET IT
Times cited: 15
Heart chamber size in zebrafish is regulated redundantly by duplicated tbx2 genes. Developmental dynamics : an official publication of the American Association of Anatomists. 2011 Academic Article GET IT
Times cited: 10
A reverse genetic approach to test functional redundancy during embryogenesis. Journal of visualized experiments : JoVE. 2010 Academic Article GET IT
Times cited: 4
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nature biotechnology. 2010 Academic Article GET IT
Times cited: 958
Non-core subunit eIF3h of translation initiation factor eIF3 regulates zebrafish embryonic development. Developmental dynamics : an official publication of the American Association of Anatomists. 2010 Academic Article GET IT
Times cited: 15
Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts. Tetrahedron letters. 2010 Academic Article GET IT
Times cited: 47
A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity. PloS one. 2010 Academic Article GET IT
Times cited: 19
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature. 2010 Academic Article GET IT
Times cited: 804
Design and Synthesis of Potential New Apoptosis Agents: Hybrid Compounds Containing Perillyl Alcohol and New Constrained Retinoids. Tetrahedron letters. 2010 Academic Article GET IT
Times cited: 16
The tbx/bHLH transcription factor mga regulates gata4 and organogenesis. Developmental dynamics : an official publication of the American Association of Anatomists. 2010 Academic Article GET IT
Times cited: 14
Gata4 directs development of cardiac-inducing endoderm from ES cells. Developmental biology. 2009 Academic Article GET IT
Times cited: 54
Design and synthesis of novel pinacolylboronate containing combretastatin 'antimitotic agent' analogues. Tetrahedron letters. 2009 Academic Article GET IT
Times cited: 14
Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis. Circulation research. 2009 Academic Article GET IT
Times cited: 36
Fishing for a WNT-PGE2 link: beta-catenin is caught in the stem cell net-work. Cell stem cell. 2009 Academic Article GET IT
Times cited: 15
Design and synthesis of (E)-1-((3-ethyl-2,4,4-trimethylcyclohex-2-enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1-enyl)ethanol. Chemical communications (Cambridge, England). 2009 Academic Article GET IT
Times cited: 12
A forward chemical screen using zebrafish embryos with novel 2-substituted 2H-chromene derivatives. Chemical biology & drug design. 2009 Academic Article GET IT
Times cited: 37
Regulation of hematopoiesis by the BMP signaling pathway in adult zebrafish. Experimental hematology. 2008 Academic Article GET IT
Times cited: 12
Synthesis of 2-substituted 2H-chromenes using potassium vinyltrifluoroborates. Tetrahedron letters. 2008 Academic Article GET IT
Times cited: 45
Embryonic Stem Cells as a Model for Cardiac Development and Disease. Drug discovery today. Disease models. 2008 Academic Article GET IT
Times cited: 6
Evolutionarily conserved gene family important for fat storage. Proceedings of the National Academy of Sciences of the United States of America. 2007 Academic Article GET IT
Times cited: 189
Gata5 and Gata6 are functionally redundant in zebrafish for specification of cardiomyocytes. Developmental biology. 2007 Academic Article GET IT
Times cited: 58
Smad1 and Smad5 differentially regulate embryonic hematopoiesis. Blood. 2007 Academic Article GET IT
Times cited: 59
Steady endothelial nitric oxide synthase expression in heart failure. Acta cardiologica. 2007 Academic Article GET IT
Times cited: 6
Smad1 expands the hemangioblast population within a limited developmental window. Blood. 2006 Academic Article GET IT
Times cited: 32
Yaf2 inhibits caspase 8-mediated apoptosis and regulates cell survival during zebrafish embryogenesis. The Journal of biological chemistry. 2006 Academic Article GET IT
Times cited: 29
Bmp2 and Gata4 function additively to rescue heart tube development in the absence of retinoids. Developmental dynamics : an official publication of the American Association of Anatomists. 2006 Academic Article GET IT
Times cited: 17
STAT5 acts as a repressor to regulate early embryonic erythropoiesis. Blood. 2006 Academic Article GET IT
Times cited: 8
BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis. Development (Cambridge, England). 2006 Academic Article GET IT
Times cited: 42
Tid1 is a Smad-binding protein that can modulate Smad7 activity in developing embryos. The Biochemical journal. 2006 Academic Article GET IT
Times cited: 7
Cloning and expression pattern of the Xenopus erythropoietin receptor. Gene expression patterns : GEP. 2005 Academic Article GET IT
Times cited: 4
Regulation of hematopoiesis by retinoid signaling. Experimental hematology. 2005 Review GET IT
Times cited: 65
Gata4 regulates the formation of multiple organs. Development (Cambridge, England). 2005 Academic Article GET IT
Times cited: 155
An Oct-1 binding site mediates activation of the gata2 promoter by BMP signaling. Nucleic acids research. 2005 Academic Article GET IT
Times cited: 23
Using the zebrafish model to study GATA transcription factors. Seminars in cell & developmental biology. 2004 Review GET IT
Times cited: 48
T-box binding sites are required for activity of a cardiac GATA-4 enhancer. Developmental biology. 2004 Academic Article GET IT
Times cited: 68
Regulation of cardiac myocyte apoptosis by the GATA-4 transcription factor. Life sciences. 2004 Review GET IT
Times cited: 61
Hematopoiesis and retinoids: development and disease. Leukemia & lymphoma. 2003 Review GET IT
Times cited: 32
Primitive erythropoiesis is regulated by Smad-dependent signaling in postgastrulation mesoderm. Blood. 2003 Academic Article GET IT
Times cited: 31
Anthracycline-induced suppression of GATA-4 transcription factor: implication in the regulation of cardiac myocyte apoptosis. Molecular pharmacology. 2003 Academic Article GET IT
Times cited: 147
Hepatocyte growth factor induces GATA-4 phosphorylation and cell survival in cardiac muscle cells. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 108
Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis. Biochemistry. 2002 Academic Article GET IT
Times cited: 24
Retinoid signaling regulates primitive (yolk sac) hematopoiesis. Blood. 2002 Academic Article GET IT
Times cited: 48
A maternal Smad protein regulates early embryonic apoptosis in Xenopus laevis. Molecular and cellular biology. 2002 Academic Article GET IT
Times cited: 15
Physical training in patients with chronic heart failure enhances the expression of genes encoding antioxidative enzymes. Journal of the American College of Cardiology. 2001 Academic Article GET IT
Times cited: 116
Angiotensin II receptor subtypes in the skeletal muscle vasculature of patients with severe congestive heart failure. Circulation. 2000 Academic Article GET IT
Times cited: 25
Anterior endoderm is sufficient to rescue foregut apoptosis and heart tube morphogenesis in an embryo lacking retinoic acid. Developmental biology. 2000 Academic Article GET IT
Times cited: 53
A role for GATA-4/5/6 in the regulation of Nkx2.5 expression with implications for patterning of the precardiac field. Developmental biology. 1999 Academic Article GET IT
Times cited: 65
Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells. Genes & development. 1999 Academic Article GET IT
Times cited: 392
Reversal of GATA-6 downregulation promotes smooth muscle differentiation and inhibits intimal hyperplasia in balloon-injured rat carotid artery. Circulation research. 1999 Academic Article GET IT
Times cited: 102
Retinoid signaling required for normal heart development regulates GATA-4 in a pathway distinct from cardiomyocyte differentiation. Developmental biology. 1999 Academic Article GET IT
Times cited: 87
Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation. Molecular and cellular biology. 1998 Academic Article GET IT
Times cited: 204
Common role for each of the cGATA-4/5/6 genes in the regulation of cardiac morphogenesis. Developmental genetics. 1998 Academic Article GET IT
Times cited: 71
Developmental biology of hematopoiesis. Hematology/oncology clinics of North America. 1997 Review GET IT
Times cited: 23
Regulation of Cardiac Gene Expression by GATA-4/5/6. Trends in cardiovascular medicine. 1997 Academic Article GET IT
Differential regulation of neurogenesis by the two Xenopus GATA-1 genes. Molecular and cellular biology. 1997 Academic Article GET IT
Times cited: 50
The human GATA-6 gene: structure, chromosomal location, and regulation of expression by tissue-specific and mitogen-responsive signals. Genomics. 1996 Academic Article GET IT
Times cited: 121
The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. Developmental biology. 1996 Academic Article GET IT
Times cited: 186
BMP-like signals are required after the midblastula transition for blood cell development. Developmental genetics. 1996 Academic Article GET IT
Times cited: 67
Negative regulation of chicken GATA-1 promoter activity mediated by a hormone response element. Molecular endocrinology (Baltimore, Md.). 1995 Academic Article GET IT
Times cited: 14
Homotypic interactions of chicken GATA-1 can mediate transcriptional activation. Molecular and cellular biology. 1995 Academic Article GET IT
Times cited: 39
GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. The Journal of biological chemistry. 1994 Academic Article GET IT
Times cited: 492
Differential regulation of the two xGATA-1 genes during Xenopus development. The Journal of biological chemistry. 1994 Academic Article GET IT
Times cited: 18
GATA-4 is a novel transcription factor expressed in endocardium of the developing heart. Development (Cambridge, England). 1993 Academic Article GET IT
Times cited: 212
A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex. Proceedings of the National Academy of Sciences of the United States of America. 1993 Academic Article GET IT
Times cited: 121
Distinct roles for the two cGATA-1 finger domains. Molecular and cellular biology. 1992 Academic Article GET IT
Times cited: 136
Interaction of the erythroid transcription factor cGATA-1 with a critical auto-regulatory element. Nucleic acids research. 1992 Academic Article GET IT
Times cited: 27
Developmental regulation of globin gene expression. Journal of cell science. Supplement. 1992 Review GET IT
Times cited: 21
Structure and promoter activity of the gene for the erythroid transcription factor GATA-1. Proceedings of the National Academy of Sciences of the United States of America. 1991 Academic Article GET IT
Times cited: 89
trans-Activation of a globin promoter in nonerythroid cells. Molecular and cellular biology. 1991 Academic Article GET IT
Times cited: 56
Structure and evolution of a human erythroid transcription factor. Nature. 1990 Academic Article GET IT
Times cited: 93
Control of globin gene transcription. Annual review of cell biology. 1990 Review GET IT
Times cited: 110
Developmental modulation of protein binding to beta-globin gene regulatory sites within chicken erythrocyte nuclei. Genes & development. 1989 Academic Article GET IT
Times cited: 44
The erythroid-specific transcription factor Eryf1: a new finger protein. Cell. 1989 Academic Article GET IT
Times cited: 456
Regulatory protein action in the neighborhood of chicken globin genes during development. Progress in clinical and biological research. 1989 Academic Article GET IT
Times cited: 3
An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes. Proceedings of the National Academy of Sciences of the United States of America. 1988 Academic Article GET IT
Times cited: 362
A promoter of the rat insulin-like growth factor II gene consists of minimal control elements. Journal of molecular biology. 1988 Academic Article GET IT
Times cited: 51

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Research

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Co-investigator Network

Funding awarded

Regulation of DNA methylation by TETs and QSER1 awarded by National Institute of Child Health & Human Development Principal Investigator 2022 - 2027
Negative feedback regulation of growth factor signaling in adult spermatogonial stem cells awarded by National Institute of Child Health & Human Development Principal Investigator 2021 - 2026
Methods for detection of dynamic intracellular signals in single adult spermatogonial stem cells awarded by National Institute of Child Health & Human Development Principal Investigator 2023 - 2025
Research Support Agreement awarded by Feinstein Institute for Medical Research, The Principal Investigator 2021 - 2023
Defining the roles of QSER1, a novel regulator of DNA methylation, in stem cell differentiation and development awarded by Tri-Institutional Stem Cell Initiative (Weill Cornell) Principal Investigator 2021 - 2023
Weill Cornell Training Program in Stem Cell Biology and Regenerative Medicine awarded by New York State Stem Cell Science (NYSTEM) Principal Investigator 2018 - 2023
A Gata456 Pipeline of Discovery awarded by National Heart, Lung, & Blood Institute Principal Investigator 2017 - 2023

H3.3-mediated epigenetic regulation of developmental bivalent genes for reprogramming and differentiation awarded by National Institute of General Medical Sciences Co-Investigator 2018 - 2023

Defining the downstream genetic networks regulated by GATA6 during human cardiogenesis using iPSC and hESC models awarded by National Heart, Lung, & Blood Institute Key Personnel 2020 - 2023

Genetic modifiers of congenital heart disease in 22q11.2 deletion syndrome awarded by National Heart, Lung, & Blood Institute Principal Investigator Subaward 2022 - 2026

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Background

education and training

Ph.D., Columbia University 1987
B.A., Northwestern University 1982

Contact

full name

Todd R. Evans

primary email

tre2003@med.cornell.edu

VIVO Weill Cornell Medical College

Todd R. Evans Associate Dean for Research

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email