Plasmacytoid dendritic cells: one-trick ponies or workhorses of the immune system? Review uri icon

Overview

abstract

  • Plasmacytoid dendritic cells (pDCs) were first described as interferon-producing cells and, for many years, their overlapping characteristics with both lymphocytes and classical dendritic cells (cDCs) created confusion over their exact ontogeny. In this Viewpoint article, Nature Reviews Immunology asks five leaders in the field to discuss their thoughts on the development and functions of pDCs--do these cells serve mainly as a major source of type I interferons or do they also make other important contributions to immune responses?

publication date

  • July 22, 2011

Research

keywords

  • Dendritic Cells

Identity

PubMed Central ID

  • PMC4157822

Scopus Document Identifier

  • 79960835493

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-04-0684

PubMed ID

  • 21779033

Additional Document Info

volume

  • 11

issue

  • 8